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Assessment of Health and Well-Being Effects Associated With the Challenging Drinking Water Situation in the Gaza Strip : Protocol for a Cross-Sectional Household Survey Study

Background: The water supply in the Gaza Strip, Palestine, has been unstable and under strain for decades, resulting in major issues with drinking water quality, reliability, and acceptability. In 2018, between 25% and 30% of Gazans did not have regular access to running water. The progressive deterioration of water infrastructure and concerns over the quality of piped water have resulted in a com

Bivalirudin vs Heparin Anticoagulation in STEMI : Confirmation of the BRIGHT-4 Results

Background: In the BRIGHT-4 (Bivalirudin With Prolonged Full-Dose Infusion During Primary PCI Versus Heparin Trial-4), anticoagulation with bivalirudin plus a 2- to 4-hour high-dose infusion after percutaneous coronary intervention (PCI) reduced all-cause mortality and bleeding without increasing reinfarction or stent thrombosis compared with heparin alone in patients with ST-segment elevation myo

Structural elaboration of a natural product : identification of 3,3'-diindolylmethane aminophosphonate and urea derivatives as potent anticancer agents

An approach involving rational structural elaboration of the biologically active natural product diindolylmethane (DIM) with the incorporation of aminophosphonate and urea moieties toward the discovery of potent anticancer agents was considered. A four-step approach for the synthesis of DIM aminophosphonate and urea derivatives was established. These novel compounds showed potent anticancer activi

Rethinking change in Japan's security policy : punctuated equilibrium theory and Japan's response to the Russian invasion of Ukraine

Change in Japanese foreign and security policy has long been characterized as “incremental”. However, Japan’s response to Russia’s 2022 invasion of Ukraine provides an opportunity to reconsider this paradigm. In the aftermath of the 2014 annexation of Crimea, then-Prime Minister Abe Shinzō chose not to put Crimea on the agenda, prioritizing instead relations with Russia. However, Prime Minister Ki

Massive star cluster formation and evolution in tidal dwarf galaxies

Context. The formation of globular clusters remains an open debate. Dwarf starburst galaxies are efficient at forming young massive clusters with similar masses as globular clusters and may hold the key to understanding their formation. Aims. We study star cluster formation in a tidal debris, including the vicinity of three tidal dwarf galaxies, in a massive gas-dominated collisional ring around N

Prediction of surface water turnover time in coastal waters using digital bathymetric information

This paper presents a new type of geographical information system (GIS) for scientific planning of coastal waters. One hypothesis in the work is that the morphometry of the coast plays a significant role for how the water system functions as a receiving water system, for example, as a receiver of industrial and urban pollution and in response to various forms of aquaculture. A digital technique fo

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) as Primary Treatment of Ovarian Cancer : A Review of the Current Literature

Background: HIPEC has been proposed as an addition in the treatment of ovarian cancer. The purpose of this review was to evaluate the evidence and use of HIPEC after cytoreductive surgery as up-front therapy for inpatients with primary ovarian cancer. Methods: We performed a search on PubMed and Web of Science. Additional studies were identified by cross-referencing past reviews and published stud

Understanding users' needs is important for the adoption of cleaner biomass cook stoves

elwood is the main source of cooking and heating energy for households in rural sub-Saharan Africa. Unfortunately, most of these households use inefficient biomass cook stoves, leading to consumption of more fuel and exposure to indoor air pollutants and associate health problems which disproportionately affect women and children. However, adoption of cleaner biomass cook stoves has remained low w

Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets

Type 2 diabetes (T2D) is the fastest growing non-infectious disease worldwide. Impaired insulin secretion from pancreatic beta-cells is a hallmark of T2D, but the mechanisms behind this defect are insufficiently characterized. Integrating multiple layers of biomedical information, such as different Omics, may allow more accurate understanding of complex diseases such as T2D. Our aim was to explore

Retrospective review of risk factors for surgical wound dehiscence and incisional hernia

Background: Several factors and patient characteristics influence the risk of surgical wound dehiscence and incisional hernia after midline laparotomy. The purpose of this study was to investigate whether a specified, or not specified, suture quota in the operative report affects the incidence of surgical wound complications and to describe the previously known risk factors for these complications

Efficient Absorbance-Based Assay for Rapid Antibiotic Susceptibility Testing of Enterobacterales

It is increasingly important to rapidly receive information on the antimicrobial susceptibility of bacteria due to the rise in antimicrobial resistance worldwide. However, traditional phenotypic methods are time-consuming. Thus, the objective of this study was to develop a rapid assay that can detect antibiotic-resistant bacterial isolates phenotypically in less than 2 h. The microplate assay used

Tailoring the Use of Central Pancreatectomy Through Prediction Models for Major Morbidity and Postoperative Diabetes : International Retrospective Multicenter Study

OBJECTIVE: To develop a prediction model for major morbidity and endocrine dysfunction after CP which could help in tailoring the use of this procedure.SUMMARY BACKGROUND DATA: Central pancreatectomy (CP) is a parenchyma-sparing alternative to distal pancreatectomy for symptomatic benign and pre-malignant tumors in body and neck of the pancreas CP lowers the risk of new-onset diabetes and exocrine

Does Peer Socialization Within Cohorts Foster Political Attitudes? A Longitudinal Study of Elite Business Students

The association between higher education and political attitudes is well-recognized, and research suggests that socialization amongst peers is one of the most probable mechanisms explaining a possible attitudinal change. However, identifying a socialization effect is difficult due to self-selection mechanisms and limitations in data availability. This article empirically investigates the underlyin

Does Emerging Carbapenem Resistance in Acinetobacter baumannii Increase the Case Fatality Rate? : Systematic Review and Meta-Analysis

BACKGROUND: In the era of rising carbapenem resistance, we aimed to investigate the change in mortality rate and positivity of carbapenemase genes in Acinetobacter baumannii.METHODS: Preferred Reporting Items for Systematic Review (PRISMA) guidelines were adopted in this systematic review. Our literature search included the Cochrane Library, Pubmed, Scopus, Web of Science, Medline, Tubitak TR Dizi

Fabrication and Electrocatalytic Evolution of Alkali-Free CoNb2O6 Thin Films for Water Oxidation via Polyoxoniobates

Fabrication of CoNb2O6 thin films was possible through spin-coating an alkali-free, aqueous solution of a polyoxoniobate ([Nb10O28]6-, Nb10) and a cobalt nitrate (Co(NO3)2), followed by annealing. The results showed that depending on the calcination conditions, minor phases of unreacted Co3O4 and β-Nb2O5 may form alongside the columbite CoNb2O6 phase. However, optimizing the calcination conditions

What we mean as what we said or would have said

We usually mean what we say, but sometimes we do not. When I ironically utter ‘What lovely weather’ on a rainy day, or mistakenly utter ‘Jim is a barn door’ instead of ‘Jim is a darn bore’, I say one thing and mean another. However, although utterances like these are not uncommon, they are greatly overshadowed by the volume of humdrum utterances of ‘There is wine in the fridge’ or ‘I really like n

Energy level offsets determine the interplay between charge and energy transfer in all-small-molecule organic solar cells

All-small-molecule organic solar cells (ASM OSCs) hold great promise in OSCs owing to their defined structures, simple purification, and good reproducibility, but are challenging for further improved efficiency. The energy level strategy has been broadly applied to obtain a better performance; however, a comprehensive understanding of the effects of energy level offset on photoexcitation dynamics

Selection bias of ideas for sustainability-oriented innovation in internal crowdsourcing

Decision biases reinforce firms’ tendency to develop innovations based on narrow economic motivations. Consequently, sustainability-oriented ideas explicitly targeting social and environmental issues are easily discarded in idea selection when trade-offs between economic and sustainability values are faced. Given the so far limited knowledge about how sustainability-oriented ideas are developed an

Shadow Area and Degrees of Freedom for Free-Space Communication

The number of degrees of freedom (NDoF) in a communication channel fundamentally limits the number of independent spatial modes available for transmitting and receiving information. Although the NDoF can be computed numerically for specific configurations using singular value decomposition (SVD) of the channel operator, this approach provides limited physical insight. In this paper, we introduce a

Using the structure of the residuals to evaluate the goodness of fit : a pedagogical case study with Newton’s law of cooling

Introductions to data analysis in university physics often focus on fitting (typically to linearised functions) and uncertainty propagation, but residuals are less commonly introduced. Structured residuals indicate that the function (theoretical description) used to fit data does not capture all the relevant elements (i.e. the theoretical description is incomplete), and can be present even when th