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Objectives. To evaluate long-term changes in acetylcholinesterase (AChE) activity in CSF and blood following donepezil treatment in relation to the concentration of donepezil and cognition in AD patients. Methods. CSF or blood (or both) samples of a total of 104 patients with mild AD were used [MMSE score 23 +/- 0.4; age 75 +/- 1 years (mean +/- SEM); n = 53 for CSF and n = 51 for plasma/red blood

Objective To examine the effectiveness of pH analysis of fetal scalp blood compared with lactate analysis in identifying hypoxia in labour to prevent acidaemia at birth. Design Randomised controlled multicentre trial. Setting Labour wards. Participants Women with a singleton pregnancy, cephalic presentation, gestational age >= 34 weeks, and clinical indication for fetal scalp blood sampling. Inter

The European Union’s sugar policy is one of the most distorting policies within the common agricultural policy. It includes import control, production quota, and export refunds to support producer price within the EU at levels high above international prices. The main beneficiaries of the support system are the EU sugar industries and EU beet growers, but they are not the only producers benefiting

Popular Abstract in Swedish Pappersbrott i planet har studerats med hjälp av den kohesiva sprick modellen ur ett experimentellt såväl som ur ett teoretiskt perspektiv. Brott i en pappersremsa erhålls när remsan i en provmaskin belastas till sin maximala bärlast. Om remsan är tillräckligt kort fås en stabil nedåtgående last-förlängnigs kurva efter det att max lasten är nådd. Det visade sig att denThe in-plane failure of paper is studied in this work by means of a cohesive crack model from experimental as well as theoretical perspectives. Localized damage at in-plane tension of short paper strips is studied for low strain rates. It is observed that under uniaxial in-plane tensile tests, the evolution of the failure is stable and the damage of the paper strip is localized into a narrow zone

In a 24-year sub-sample taken from a 42-year period of study (1950-1991), hip fracture incidence was analysed from a defined catchment area within one hospital. During this time, 8,256 hip fractures occurred in a generated risk population of 1,915,571 person-years. Crude incidence increased three-fold in women and five-fold in men. In men, the age-specific increase was twice as large as the age dr

Wilms Tumor suppressor protein (WT1) is a transcription factor that is involved in a variety of developmental functions during organ development. It is also implicated in the pathology of several different cancer forms. The protein contains four C(2)H(2)-type zinc fingers and it specifically binds GC-rich sequences in the promoter regions of its target genes, which are either up or down regulated.

Despite an abundance of peptides inside a cell, only a small fraction is ultimately presented by HLA-I on the cell surface. The presented peptides have HLA-I allomorph-specific motifs and are restricted in length. So far, detailed length studies have been limited to few allomorphs. Peptide-HLA-I (pHLA-I) complexes of different allomorphs are qualitatively and quantitatively influenced by tapasin t

The purpose of this paper is to provide insight into how companies work during packaging development to reduce negative environmental impact along supply chains, and to compare their practical approaches with the theoretical concepts presented in the literature. The research approach is explorative and based on nine cases in the food and manufacturing industries in Sweden. Data were collected from

The author sets out to analyse a number of representations of the biblical Hagar figure in African American and white American culture. Spivak (1988) has problematized the marginalization concept with regard to the study of the third world subject, arguing that knowledge always expresses the interests of the knowledge producers, and that Western academic research is always colonial. The aim of the

ActiGraph acceleration data are processed through several steps (including bandpass filtering to attenuate unwanted signal frequencies) to generate the activity counts commonly used in physical activity research. We performed three experiments to investigate the effect of sampling frequency on the generation of activity counts. Ideal acceleration signals were produced in the MATLAB software. There

Objectves To obtain information on the mechanisms of female rat micturition using a model in which pressure was measured in the bladder and distal part of the urethra corresponding to the location of the rhabdosphincter, providing information on the role of the sphincter in opening and closing the urethral lumen. Materials and Methods A micturition reflex was induced in adult anaesthetized (chlora

Since the early 1990s, an increasing proportion of barnacle geese, Branta leucopsis, bound for breeding sites in the Russian Arctic delay their departure from the wintering quarters in the Wadden Sea by 4 weeks. These late-migrating geese skip spring stopover sites in the Baltic traditionally used by the entire population. Individual geese from an arctic colony tracked by satellite or light-level

Popular Abstract in Swedish Denna avhandling behandlar två ämnen inom trådlös kommunikation: interferens mellan frekvenshoppande (FH) nätverk och fleranvändardiversitet. I arbetet på FH nätverk undersöks ett system där frekvenshopp används för att möjliggöra samtidig tillgång till kanalen för multipla okoordinerade nätverk. Detta åstadkoms genom att frekvenshoppen sker varje gång ett ny paket skaThis thesis deals with two topics in wireless communications: interference between frequency-hopping (FH) networks, and multiuser diversity. The work on FH treats a system where FH is used to provide simultaneous access to the channel for multiple uncoordinated wireless networks. This is achieved by performing frequency hops on a packet-by-packet basis, and letting the sequence of hopping frequen

Metastatic castration-resistant prostate cancer is today incurable. Conventional imaging methods have limited detection, affecting their ability to give an accurate outcome prognosis, and current therapies for metastatic prostate cancer are insufficient. This inevitably leads to patients relapsing with castration-resistant prostate cancer. Targeting prostate-specific antigens whose expression is c

This paper investigates the FPGA resources for the implementation of in-cycle closed-loop combustion control algorithms. Closed-loop combustion control obtains feedback from fast in-cylinder pressure measurements for accurate and reliable information about the combustion progress, synchronized with the flywheel encoder. In-cycle combustion control requires accurate and fast computations for their