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Human epidermal energy metabolism is functionally anaerobic

We have reported that epidermal Langerhans cells possess an H+-extruding mechanism signalling their existence in an anaerobic environment. This study highlights the energy metabolism of human epidermis. In their habitual state the keratinocytes contain more lactate than do most other cell types. Their lactate production in vitro is vigorous and independent of oxygen and most of it is released to t

Compton scattering from the deuteron and extracted neutron polarizabilities

Differential cross sections for Compton scattering from the deuteron were measured at MAX-Lab for incident photon energies of 55 and 66 MeV at nominal laboratory angles of 45degrees, 125degrees, and 135degrees. Tagged photons were scattered from liquid deuterium and detected in three NaI spectrometers. By comparing the data with theoretical calculations in the framework of a one-boson-exchange pot

Development of Laser-Spectroscopic Techniques for New Detection Schemes in Combustion Diagnostics

Popular Abstract in Swedish Förbränning förknippas av många som förlegat. Att utvinna energi genom att ”elda” har människan gjort under årtusenden, men trots det bestod Sveriges totala energiproduktion 2004 till 52 % av förbränning. De flesta bilar, båtar, flyg och i vissa fall även tåg utnyttjar den kemiskt lagrade energin i fossila bränslen. Uppvärmningen av bostäder är inte heller att förringa,The thesis work, aimed at the development of laser-spectroscopic detection schemes, consists of three parts, concerned with the development and application of different techniques. The development of UV filtered Rayleigh scattering (FRS) for thermometry and fuel/air ratio measurements, using a frequency tripled, single-longitudinal-mode alexandrite laser at ~254 nm together with an isotopically en

Continuous stand-alone controllable aerosol/cloud droplet dryer for atmospheric sampling

We describe a general-purpose dryer designed for continuous sampling of atmospheric aerosol, where a specified relative humidity (RH) of the sample flow (lower than the atmospheric humidity) is required. It is often prescribed to measure the properties of dried aerosol, for instance for monitoring networks. The specific purpose of our dryer is to dry cloud droplets (maximum diameter approximately

A prospective registry of European haemophilia B patients receiving nonacog alfa, recombinant human factor IX, for usual use.

Summary. Nonacog alfa, a recombinant factor IX (FIX) used for the treatment of haemophilia B, was approved in Europe in 1998. In accordance with European Medicines Agency requirements, a registry study was conducted from 2002 to 2009. A reformulated iso-osmotic version was approved for European use in 2007. This study was conducted to evaluate the safety of nonacog alfa in a usual care setting, an

Organization of straw-to-energy systems in Ukraine and Scandinavia

Ukraine (UA) faces broad needs for energy security enhancement, energy diversification, revitalization of agriculture, and improvements in the state of the environment. UA has large biomass-for-bioenergy potential, which can be leveraged to contribute to local/regional energy self-sufficiency, rural development and diversification, and environmental improvement via fossil fuel substitution with lo

Growth and interactions of arbuscular mycorrhizal fungi in soils from limestone and acid rock habitats

Arbuscular mycorrhizal (AM) development in different soil types, and the influence of AM fungal hyphae on their original soil were investigated. Plantago lanceolata, which can grow in soils of a very wide pH range, was grown in two closely related limestone soils and an acid soil from rock habitats. Plants were colonised by the indigenous AM fungal community. The use of compartmented systems allow

Combined magnetic and structural investigation of nano crystalline iron oxides: The interplay between crystal size and phase composition during FeS2 oxidation

The oxides that form during thermal oxidation of natural FeS2 (pyrite and marcasite) consist of nanometer-sized crystals of alpha-Fe2O3 and gamma-Fe2O3. This is shown with heating experiments that were made up to 650 degrees C, which resembles temperatures used in metallurgical processes. It is shown that magnetic measurements can play a key role in the investigation of this reaction, due to the u

New species of Uroglena and Ochromonas (Chromulinales, Chrysophyceae) from Estonia

During the spring of 2003 ninety-five water bodies in southeastern Estonia were surveyed for chrysophytes. The sampling was carried out as the ice broke up, when, within two weeks, the water temperature rose from 3 degrees C to 13 degrees C. Large lakes to small pools of different water chemistry were investigated. The plankton collected was studied alive within a few hours after sampling. Prepara

Integration potential, resource efficiency and cost of forest-fuel-based biorefineries

A multidisciplinary study of the implementation potential of a biorefinery, using forestry residues as feedstock, is performed by assessing techno-economic factors, system integration and feedstock supply. The process is based on biochemical conversion of logging residues to produce ethanol, biogas, pellets, heat and electricity. Nine models were designed in Aspen Plus based on the available feeds

Inhibitor development in hemophiliacs: The roles of genetic versus environmental factors

Approximately 5 to 7% of patients with hemophilia A have inhibitory antibodies to factor (F) VIII, which increases to similar to 13% in patients with severe disease. The strongest determinant of the risk of inhibitor development identified is the type of mutation in the FVIII gene that gives rise to the disease. However, accumulating evidence clearly indicates that other genetic factors (e.g., maj

An international dosimetry exchange for boron neutron capture therapy, Part I : Absorbed dose measurements

An international collaboration was organized to undertake a dosimetry exchange to enable the future combination of clinical data from different centers conducting neutron capture therapy trials. As a first step (Part I) the dosimetry group from the Americas, represented by MIT, visited the clinical centers at Studsvik (Sweden), VTT Espoo (Finland), and the Nuclear Research Institute (NRI) at Rez (

E-business and e-supply strategy in small and medium sized businesses (SMEs)

The purpose of this research was to investigate e-business and e-supply strategies in Scottish small- and medium-sized enterprises (SMEs). The paper reviews academic literature and recent survey reports on the degree of e-business adoption in the UK and Republic of Ireland. The qualitative methodology undertaken is described, findings are discussed and implications from this study for e-business s

Interdialytic weight gain and ultrafiltration rate in hemodialysis: Lessons about fluid adherence from a national registry of clinical practice

Excessive interdialytic weight gain (IWG) and ultrafiltration rates (UFR) above 10 mL/h/kg body weight imply higher morbidity and mortality. This study aimed to estimate the prevalence of high fluid consumers, describe UFR patterns, and describe patient characteristics associated with IWG and UFR. The Swedish Dialysis DataBase and The Swedish Renal Registry of Active Treatment of Uremia were used

Monitored versus experience-based perceptions of environmental change: evidence from coastal Tanzania

The impacts of climate change are likely to exacerbate many problems that coastal areas already face. In this study, we used multinomial logistic regression to examine human perception of climate change based on a cross-sectional survey of 1253 individuals in coastal regions of Tanzania. This was complemented with time series analysis of 50-year meteorological data. The results indicate that self-

End-stage renal disease associated with prophylactic lithium treatment.

The primary aim of this study was to estimate the prevalence of lithium associated end-stage renal disease (ESRD) and to compare the relative risk of ESRD in lithium users versus non-lithium users. Second, the role of lithium in the pathogenesis of ESRD was evaluated. We used the Swedish Renal Registry to search for lithium-treated patients with ESRD among 2644 patients with chronic renal replacem

Crop rotations including ley and manure can promote ecosystem services in conventional farming systems

Agricultural intensification has contributed substantially to the increase in food production, but has come at the expense of soil degradation and environmental problems. Management of soil based ecosystem services need to be considered in agricultural management since intensive management implies not only costs to the farmer but also to society. In this study we used data from four long-term (55

Prenatal diagnosis of haemophilia in Sweden now more commonly used for psychological preparation than termination of pregnancy.

The aims of the study were to define the frequency, outcome and reasons for prenatal diagnosis (PND) in Sweden during a 30-year period in order to study trends and changes. The study population, from the Swedish nationwide registry of PND of haemophilia, consisted of 54 women, compromising >95% of all, who underwent PND (n = 90) of haemophilia during 1977-2013. PND was performed by amniocentesis (