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Detection of Crosslinks within and between Proteins by LC-MALDI-TOFTOF and the Software FINDX to Reduce the MSMS-Data to Acquire for Validation.

Lysine-specific chemical crosslinking in combination with mass spectrometry is emerging as a tool for the structural characterization of protein complexes and protein-protein interactions. After tryptic digestion of crosslinked proteins there are thousands of peptides amenable to MSMS, of which only very few are crosslinked peptides of interest. Here we describe how the advantage offered by off-li

Cost and outcome: comparisons of two alternative bypassing agents for persons with haemophilia A complicated by an inhibitor.

The development of inhibitory antibodies to factor VIII is a serious complication of haemophilia. Two haemostatic agents with different bypassing mechanisms have been used in the treatment of patients with inhibitors: activated prothrombin complex concentrate (aPCC) and recombinant factor VIIa (rFVIIa). The objective was to compare cost and outcome of aPCC and rFVIIa in the treatment of joint blee

QCD Phenomenology of Heavy Particle Dynamics

Popular Abstract in Swedish Teorin för den starka kraften, kvantkromodynamik eller QCD, behandlas här med både perturbativa och icke-perturbativa metoder. Speciellt produktions- och hadroniseringsdynamiken hos tunga partiklar studeras. Dessa partiklar innefattar tunga kvarkar (charm, botten och top), gaugebosoner, leptokvarkar och supersymmetriska partiklar. När tunga långlivade kvarkar (d.v.s. cIn this thesis the phenomenology of Quantum Chromo Dynamics (QCD) is studied in a variety of circumstances from both perturbative and non-perturbative perspectives. The main emphasis is on the production and hadronization of heavy particles, specifically heavy quarks, gauge bosons, leptoquarks and supersymmetric particles. In the hadroproduction of long-lived heavy quarks (i.e. charm and bottom)

Presumption of Equality as a Requirement of Fairness

Abstract in UndeterminedPresumption of Equality enjoins that individuals be treated equally in the absence of discriminating information. My objective in this paper is to make this principle more precise, viewing it as a norm of fairness, in order to determine why and under what conditions it should be obeyed.Presumption norms are procedural constraints, but their justification might come from the

Gender and Social Disparities in Esophagus Cancer Incidence in Iran, 2003-2009: A Time Trend Province-level Study.

Background: Esophagus cancer (EC) is among the five most common cancers in both sexes in Iran, with an incidence rate well above world average. Social rank (SR) of individuals and regions are well-known independent predictors of EC incidence. The aim of current study was to assess gender and social disparities in EC incidence across Iran's provinces through 2003-2009. Materials and Methods: Data o

Industrial robot motion control with real-time Java and EtherCAT

Safe object-oriented programming languages like Java provide a much more programmer-friendly environment than the low-level languages in which real-time and embedded software have traditionally been implemented. Therefore, with the recent popularity of real-time Java, it is interesting to examine its feasibility for robot motion control. We have implemented a motion control system, and an applica

Simulation of robot paths and heat effects in welding

Popular Abstract in Swedish Svetsning är en av de viktigaste tillämpningarna för robotar är inom tillverkningsindustrin. Normalt så programmeras roboten genom att operatören guidar manuellt robotarmen mellan de olika robotkoordinaterna. För att förbättra noggrannheten vid programmeringen kan man använda ett simuleringsverktyg, så kallat Computer Aided Robotics (CAR). Simulering kan även vara ett kThe objective of this thesis is to develop a simulation tool and a method by which robot trajectories, temperature histories, residual stresses and distortion can be analysed and optimized off-line. This was performed by integrating robot simulation software with finite element analysis software. A special interface was created which facilitated information exchange between the two software progra

Azep gas turbine combined cycle power plants thermo-economic analysis

Conventional power plants based on fossil fuel without CO2 capture produce flue gas streams with concentrations Of CO2 between 3% and 15%, contributing to the threat of increasing global warming. Existing capture technologies such as post-combustion flue gas treatment using chemical absorption or pre-combustion carbon removal suffer from significant efficiency penalties as well as major increase i