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Do nuclei go pear-shaped? Coulomb excitation of Rn-220 and Ra-224 at REX-ISOLDE (CERN)

The IS475 collaboration conducted Coulomb-excitation experiments with post-accelerated radioactive Rn-220 and Ra-224 beams at the REX-ISOLDE facility. The beam particles (E-beam: 2.83 MeV/u) were Coulomb excited using Ni-60, Cd-14, and Sn-120 scattering targets. De-excitation gamma-rays were detected employing the Miniball array and scattered particles were detected in a silicon detector. Exploiti

Hard real-time guarantees in feedback-based resource reservations

Resource reservation is a technique that allows isolating applications from interfering among each other. In the most classic setting, this method requires the periodic allocation of a given budget of resource over time. However, in reality, the actual budget allocation may deviate from its ideal value. Examples of causes of this deviation are: the presence of a system tick, the usage of shared re

Genetic networks with canalyzing Boolean rules are always stable

We determine stability and attractor properties of random Boolean genetic network models with canalyzing rules for a variety of architectures. For all power law, exponential, and flat in-degree distributions, we find that the networks are dynamically stable. Furthermore, for architectures with few inputs per node, the dynamics of the networks is close to critical. In addition, the fraction of gene

Amplification of Molecular Recognition Signal on Imprinted Polymers Using Hybridization Chain Reaction

Hybridization chain reaction (HCR)-based amplification strategies have shown excellent prospects of application in detection thanks to its non-enzymatic and isothermal features. For protein biomarker detection, most bioanalytical assays are dependent on antibodies or aptamers to provide specific recognition to allow single strand DNA (ssDNA) to initiate specific HCR to realize effective signal amp

2D polarization imaging as a low-cost fluorescence method to detect α-synuclein aggregation ex vivo in models of Parkinson’s disease

A hallmark of Parkinson’s disease is the formation of large protein-rich aggregates in neurons, where α-synuclein is the most abundant protein. A standard approach to visualize aggregation is to fluorescently label the proteins of interest. Then, highly fluorescent regions are assumed to contain aggregated proteins. However, fluorescence brightness alone cannot discriminate micrometer-sized region

Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps

Triosephosphate isomerase (TIM) is a key enzyme in glycolysis that catalyses the interconversion of glyceraldehyde 3-phosphate and dihydroxy-acetone phosphate. This simple reaction involves the shuttling of protons mediated by protolysable side chains. The catalytic power of TIM is thought to stem from its ability to facilitate the deprotonation of a carbon next to a carbonyl group to generate an

Translation, adaptation and testing of an emergency care satisfaction scale in Swedish pediatric emergency departments

Background: Pediatric healthcare today shows a rising demand for research focusing on children’s perspectives on and consumer satisfaction with the nursing care they receive. Therefore, the purpose of this study was to translate and adapt the Consumer Emergency Care Satisfaction Scale (CECSS), a paper-based, self-administered 19-item questionnaire originally developed in the United States and targ

Computational simulation data using the Lattice Boltzmann method to generate correlations for gas diffusion layer parameters

Analyzing the fluid behavior in complex porous media like gas diffusion layers (GDLs) in polymer electrolyte fuel cells (PEFCs) can be accurately done using the lattice Boltzmann method (LBM). This article shows the data obtained from a study in which diffusion parameters such as porosity, gas phase tortuosity and diffusibility are computed considering simulated porous media [1]. The data were com

Using Patchy Particles to Prevent Local Rearrangements in Models of Non-equilibrium Colloidal Gels

Simple models based on isotropic interparticle attractions often fail to capture experimentally observed structures of colloidal gels formed through spinodal decomposition and subsequent arrest: the resulting gels are typically denser and less branched than their experimental counterparts. Here, we simulate gels formed from soft particles with directional attractions ("patchy particles"), designed

Macro-pulse generation in a storage-ring free-electron laser : A single-particle plus FEL numerical approach

In a storage-ring free-electron laser (FEL), the onset and growth of intra-cavity power at the resonator wavelength can be naturally accompanied by coherent emission at higher harmonics. Contrary to what happens in singlepass linac-based devices, the electron beam is re-circulated in the storage ring and, while the microbunching becomes "thermalized" from turn to turn, the evolution of other bunch

2HDME : Two-Higgs-Doublet Model Evolver

Two-Higgs-Doublet Model Evolver (2HDME) is a C++ program that provides the functionality to perform fast renormalization group equation running of the general, potentially CP-violating, 2 Higgs Doublet Model at 2-loop order. Simple tree-level calculations of masses; calculations of the oblique parameters S, T and U; different parameterizations of the scalar potential; tests of perturbativity, unit

Optimal power and efficiency of single quantum dot heat engines : Theory and experiment

Quantum dots (QDs) can serve as near perfect energy filters and are therefore of significant interest for the study of thermoelectric energy conversion close to thermodynamic efficiency limits. Indeed, recent experiments in [Nat. Nano. 13, 920 (2018)1748-338710.1038/s41565-018-0200-5] realized a QD heat engine with performance near these limits and in excellent agreement with theoretical predictio

Geophysical investigation of arural water point installation program in Nampula province, Mozambique

There are many projects in Mozambique for poverty reduction. One of these projects is funded by Millennium Challenge Account (MCA) and is aimed to install a total of 600 rural water points in the province of Nampula and Cabo Delgado in crystalline rock zone. Each water point consists of a drilled well, a water pump and a communal washing basin. Vertical Electrical Sounding (VES) was used for asses

Detection of Copy Number Aberration and Tumor Fraction in Archival Cervical Specimens from Ovarian Cancer Patients using Shallow Whole Genome Sequencing.

Ovarian cancer, often called the silent killer due to its diffuse symptoms at early stage, poor prognosis after treatments and high mortality, is also a heterogeneous disease consisting of different histological subtypes with potentially different origins. About 90% of all cases derive from epithelial cells and high-grade serous ovarian carcinoma (HGSOC) is the most common and aggressive form of e

Approximate Counting of k-Paths : Simpler, Deterministic, and in Polynomial Space

Recently, Brand et al. [STOC 2018] gave a randomized mathcal O(4kmϵ-2-time exponential-space algorithm to approximately compute the number of paths on k vertices in a graph G up to a multiplicative error of 1 ± ϵ based on exterior algebra. Prior to our work, this has been the state-of-the-art. In this article, we revisit the algorithm by Alon and Gutner [IWPEC 2009, TALG 2010], and obtain the foll

Testing Self-Adaptive Software with Probabilistic Guarantees on Performance Metrics : Extended and Comparative Results

This paper discusses methods to test the performance of the adaptation layer in a self-adaptive system. The problem is notoriously hard, due to the high degree of uncertainty and variability inherent in an adaptive software application. In particular, providing any type of formal guarantee for this problem is extremely difficult. In this paper we propose the use of a rigorous probabilistic approac