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Refractive and diffractive neutron optics with reduced chromatic aberration

Thermal neutron beams are an indispensable tool in physics research. The spatial and the temporal resolution attainable in experiments are dependent on the flux and collimation of the neutron beam which remain relatively poor, even for modern neutron sources. These difficulties may be mitigated by the use of optics for focusing and imaging. Refractive and diffractive optical elements, e.g. compoun

FROM SERUM TO TISSUE: GALECTIN-BINDING GLYCOFORMS OF SERUM GLYCOPROTEINS AS FUNCTIONAL BIOMARKERS

Popular Abstract in Swedish Cellerna i kroppen är uppbyggda av fyra olika byggstenar: DNA, proteiner, fetter samt kolhydrater. Kolhydrater förknippas framförallt med energi och det pågår en intensiv debatt om kolhydraternas vara eller icke vara i vår kost. Kolhydraterna har dock också en helt annan funktion, en som är obestridligt oumbärlig för alla levande organismer. I denna roll förekommer de bGalectins are small soluble proteins defined by a conserved sequence motif that forms a defining β-galactoside binding site shared among galectins; adjacent binding sites give each galectin a unique fine specificity for a specific subset of galactose containing glycans. A wealth of data now suggests important roles of galectins in both cancer and inflammation. The aim of this project is to get a c

EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjogren's syndrome

Objectives To develop a score for assessment of patients' symptoms in primary Sjogren's syndrome (SS): the EULAR SS Patient Reported Index (ESSPRI). Methods Dryness, pain, somatic and mental fatigue were identified as the main symptoms of patients with primary SS, in studies developing the Profile of Fatigue and Discomfort (PROFAD) and Sicca Symptoms Inventory (SSI). It was suspected that a single

Serotonin transporter gene polymorphisms: Effect on serotonin transporter availability in the brain of suicide attempters

The efficacy of serotonin reuptake inhibitors in depression and anxiety disorders suggests the gene coding for the serotonin transporter (5-HTT), SLC6A4, as a candidate of importance for these conditions. Positive findings regarding associations between polymorphisms in SLC6A4 have been reported, indicating that these polymorphisms may influence anxiety-related personality traits, as well as the r

Bolagsskatt - hur svenska företags effektiva skattesats kan påverkas

Vid en diskussion om nivån på den svenska bolagsskatten är det av stor vikt att avgöra huruvida diskussionen rör den nominella eller den effektiva skattesatsen. Den nominella skattesatsen uppgår till 28 procent och återfinns i 65 kap. 14 § IL. Den effektiva skattesatsen är däremot inte given utan kan i viss utsträckning påverkas, eftersom den bestäms genom att dividera skatt på årets resultat med

Protecting the Unprotectable: Humanitarian Crisis and the International Community’s Kantian Responsibility to Protect in North Korea

The famine in the Democratic People’s Republic of Korea has once again reached a point of emergency wherein the international community has a moral duty to protect the population from their government. Although the member states of the United Nations have affirmed a global Responsibility to Protect, the ways in which that responsibility are carried out are often contradictory and help to sustain t

Mänskligt värde och dess betydelse för mänskliga rättigheter

The foundation in which human rights are grounded is the idea of human dignity. Human rights are based on the idea that we as humans have an equal inherent dignity, which grants us rights. That an inherent human dignity exists is however something not everyone agrees upon. That is why I in this essay analyze the importance of human dignity for human rights. In order to analyze this, I discuss whet

Overload effects on fatigue crack-tip fields under plane stress conditions: surface and bulk analysis

The surface crack opening displacements are characterised by digital image correlation for a (thin) plane stress 316 stainless steel compact tension sample subjected to an overload event. This supports a traditional plasticity-induced closure interpretation showing a knee in the closure response prior to overload, an absence of closure in the accelerated growth regime followed by accentuated closu

Social influence interpretation of interpersonal processes and team performance over time using Bayesian model selection

The team behavior literature is ambiguous about the relations between members’ interpersonal processes—task debate and task conflict—and team performance. From a social influence perspective, we show why members’ interpersonal processes determine team performance over time in small groups. Together, over time, dissenting in-group minorities who share information (via debate) with majorities, who s

Challenges in the Modeling of Wound Healing Mechanisms in Soft Biological Tissues

Numerical models have become one of the most powerful tools in biomechanics and mechanobiology allowing highly detailed simulations. One of the fields in which they have broadly evolved during the last years is in soft tissue modeling. Particularly, wound healing in the skin is one of the processes that has been approached by computational models due to the difficulty of performing experimental in

Powerful scriptable ray tracing package xrt

We present an open source python based ray tracing tool that offers several useful features in graphical presentation, material properties, advanced calculations of synchrotron sources, implementation of diffractive and refractive elements, complex (also closed) surfaces and multiprocessing. The package has many usage examples which are supplied together with the code and visualized on its web pag

EuraHS: the development of an international online platform for registration and outcome measurement of ventral abdominal wall hernia repair

Although the repair of ventral abdominal wall hernias is one of the most commonly performed operations, many aspects of their treatment are still under debate or poorly studied. In addition, there is a lack of good definitions and classifications that make the evaluation of studies and meta-analyses in this field of surgery difficult. Under the auspices of the board of the European Hernia Society

Enhancing the resolution of brain MRIs using deep learning.

Magnetic resonance imaging (MRI) is a medical imaging technique used to generate 3D cross-sections of body parts for medical diagnosis and monitoring. MRI scanners have a resolution that depends on the strength of their magnetic field, measured in Teslas (T). Most clinical scanners have a resolution of 1.5T and 3T resolution is used in wealthy hospitals and for research. A few research centers als

The impact of human constructions on the areal extent of Italian Tuscany forests

Abstract Trying to preserve the forest is an important issue considering its tremendous impact on the ecosystem and subsequently on humans and their lives. On the other hand, humans have changed the area of the forest in different ways. Therefore, investigating the human impact and helping to prevent the destruction of the forest plays a vital role in preserving biodiversity and maintaining ecosys

Den svenska medierapporteringen av det amerikanska presidentvalet 2024

The essay examines what way the Swedish news media framed the 2024 American presidential election. The aim of the thesis is guided by framing theory and mediatization theory as well as previous research. The aim of the essay is to examine if the Swedish news media reporting on the American election was dominated by a strategic or a political focus. This has a direct connection to whether the media

Janus kinase 1 inhibitors for treating immune checkpoint inhibitor-induced enterocolitis - report of two filgotinib-treated cases and literature review

BACKGROUND AND PURPOSE: Treatment of cancer with immune checkpoint inhibitors (ICIs) entails a risk of immune-related adverse events (irAEs). Data on the treatment of immune-related enterocolitis (irEC) in patients with inadequate symptom control after treatment with standard therapy including corticosteroids, infliximab, and vedolizumab are scarce. Based on limited data, recommendations include t

Smart‐Mix or Stupid Assurances? : How Businesses Used Voluntary Initiatives to (De)Legitimize Supply Chain Regulation

Mandatory human rights and environmental due diligence (HREDD) policies seem to represent a pathbreaking shift from voluntary measures to binding rules for global supply chains. Yet these policies endorse a “smart-mix” of voluntary and mandatory measures, and risk over-reliance on questionable private-sector assurances. In this paper, we ask how businesses framed these private/voluntary efforts in

From Experimental Studies to Predictive Machine Learning Modelling : Polypropylene Fibre Reinforced Concrete

This study investigates the influence of polypropylene fibres (PF) on concrete performance across a finely resolved dosage spectrum (0.0–2.0% by cement mass, in 0.1% increments) using 2,100 laboratory specimens. The experimental programme evaluated compressive strength, tensile strength (flexural and splitting), modulus of elasticity, and water penetration depth. Predictive modelling was conducted