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G protein-coupled receptor 30 (GPR30), also named G protein-coupled estrogen receptor (GPER), and the β1-adrenergic receptor (β1AR) are G protein-coupled receptors (GPCR) that are implicated in breast cancer progression. Both receptors contain PSD-95/Discs-large/ZO-1 homology (PDZ) motifs in their C-terminal tails through which they interact in the plasma membrane with membrane-associated guanylat

This paper formalizes the use of integral and differential cumulants for measurements of multiparticle event-by-event transverse momentum fluctuations, rapidity fluctuations, as well as net-charge fluctuations. This enables the introduction of multiparticle balance functions, defined based on differential correlation functions (factorial cumulants), that suppress two- and three-prong resonance dec

This paper mainly discussed the motor and converters' health indexing. The health index gives the idea about the present condition or age compared to the healthy system. The objective of this paper is to present the health index (HI) calculation method for PMSM and converters to identify the real-time health of the device. There are many articles available for the transformer health index calculat

In this didactic paper, we present a theoretical modeling framework, called the G-function, that integrates both the ecology and evolution of cancer to understand oncogenesis. The G-function has been used in evolutionary ecology, but has not been widely applied to problems in cancer. Here, we build the G-function framework from fundamental Darwinian principles and discuss how cancer can be seen th

In this report we show that phage displayed antibodies can be selected based on dissociation rate constants, using a BIAcore(TM) biosensor. To demonstrate the principle, two Fab phage stocks displaying antibodies specific for hen egg lysozyme or phenyloxazolone were mixed in a ratio of 1:10 and injected over the biosensor chip containing immobilized lysozyme. Antigen-specific bound phages were elu

A mechanochemical method (grinding the components without added water - dry grinding, followed by further grinding in the presence of minute amount of water or NaOH solution - wet grinding) was used in this work for the preparation and intercalation of CaFe-layered double hydroxides (LDHs). Both the pristine LDHs and the amino acid anion (cystinate and tyrosinate) intercalated varieties were prepa

Abstract in UndeterminedThe purpose of this paper is to report on the development of a methodology and an associatedmeasurement instrument for diagnosing innovation excellence, and to show how this methodology wasapplied in a case study. The conceptual model behind the measurement instrument has been developedbased on the specific enabler criteria and criteria parts from the European Excellence Mo

The concept of topology has become a cornerstone in the project of widening the ontological register in both ANT and human geography. The seminal starting point has for many years been ‘Regions, networks and fluids’ by Annemarie Mol and John Law from 1994, an article that for instance influenced John Urry’s outline of a global complexity. In the article, two familiar topologies, the region and the

The analysis of interconnected systems is a large and growing field, with successful applications in a wide range of natural and synthesized systems. Biomolecular networks, power grids and human social dynamics have all been the subject of study through the lens of network dynamics, with impressive results. The work presented in this thesis takes the form of four research papers all focusing in di

A general framework for the study of robust synchronisation in large-scale networks is provided. Agents are represented as a common nominal linear time-invariant (LTI) single-input-single-output (SISO) system with simple poles on the imaginary axis, subject to LTI SISO stable multiplicative perturbations. The agents exchange information in order to achieve output-synchronisation, namely steer thei

This paper develops an hourly forward curve for power markets where the intra-day and intra-week shapes (profiles) depend on the level of the hydrological balance. The shaping model is based on a feed-forward Artificial Neural Network (ANN), which is trained on a historical data set of hourly electricity spot prices from the Nord Pool market and weekly measurements of the Nordic hydrological balan

Recently a new approach to photoemission, EXAFS and electron scattering has been developed. The correlations between target electrons are separated from the active electron-target electron correlations, and the damping effects are coming out explicitly. The theory uses van Hove diagonal Green's functions and projection operator techniques, not the usual diagram expansions. By omitting from the sta

This thesis is concerned with various aspects of the constitutive modeling of plasticity. Both theoretical issues and issues related to the numerical implementation of the constitutive models are addressed. An approach to the modeling of kinematic hardening plasticity when large strains are present, taking the microstructure into account, is developed. Kinematic hardening is modeled using a varia

Multi-sample anti-aliasing is a popular technique for reducing geometric aliasing (jagged edges) and is supported in all modern graphics processors. With multi-sampling anti-aliasing, visibility and depth are sampled more than once per pixel, while shading is done only once per pixel per primitive. Although this significantly reduces the appearance of jagged edges around object boundaries, the ima

AC-DC converters are mostly used as power supplies for microelectronic systems, battery chargers, wind energy applications, electric appliances in household and dc motor drives. Switched-capacitor (SC) network based converters can be good solution to the challenges of 21st century having high voltage conversion ratio and low EMI emissions. The application of this type of converters is in microproc

Extreme Value Theory (EVT) is the state-of-the-art method for proactive prediction of accident frequency from traffic interactions on a microscopic scale. The main advantage of using EVT is to predict unobserved critical events based on one or more Surrogate Measures of Safety (SMoS) (single- or multivariate EVT) through a mathematical extrapolation of extreme interactions. Such interactions are q

Objective: Emergency department (ED) staff need to rapidly establish accurate diagnosis and management for children with arrhythmias. Limited data are available on the presenting features, epidemiology and management of arrhythmias encountered in the ED. The aim of this study was to characterise the incidence, presenting features, management and outcomes of arrhythmias at a large tertiary children