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Assessment of Mobility Conditions Using Geographic Information System in the West Bank Territory: The Case of Bethlehem – Ramallah Route

This research paper analyses and assesses the impacts of the Israeli imposed physical obstructions on the mobility of the Palestinians in the West Bank, using a case study focused on the Bethlehem – Ramallah route. Arguably, the prevailing Israeli imposed physical obstructions, or mobility restrictions, in the West Bank territory have negative implications on the articulation of sustainable Palest

Adjustment of a sparse and irregular reference rate matrix

Regional sex-specific rates of a rare disease often show conspicuous fluctuations over conventional strata of age and calendar time. In a cohort study, when such rates are used as references in the calculation of the expected number of cases, the accumulated person-time of the study cohort may somewhat haphazardly contribute to the result. For example, only the person-time observed in the strata w

Incremental runtime-generation of optimisation problems using RAG-controlled rewriting

In the era of Internet of Things, software systems need to interact with many physical entities and cope with new requirements at runtime. Self-Adaptive systems aim to tackle those challenges, often representing their context with a runtime model enabling better reasoning capabilities. However, those models quickly grow in size and need to be updated frequently with small changes due to a high num

Central exclusive production of the scalar χc meson at the Fermilab Tevatron, BNL RHIC, and CERN LHC energies

We calculate several differential distributions for exclusive double-diffractive χc(0++) production in the proton-antiproton collisions at the Tevatron and in proton-proton collisions at RHIC and LHC. We use unintegrated gluon distributions (UGDFs) within the kt-factorization approach. The g*g*→χc(0++) transition vertex is calculated as a function of gluon virtualities via the standard perturbativ

Structural analysis of a complex between small ubiquitin-like modifier 1 (SUMO1) and the ZZ domain of CREB-binding protein (CBP/p300) reveals a new interaction surface on SUMO

We have recently discovered that the ZZ zinc finger domain represents a novel small ubiquitin-like modifier (SUMO) binding motif. In this study we identify the binding epitopes in the ZZ domain of CBP (CREB-binding protein) and SUMO1 using NMR spectroscopy. The binding site on SUMO1 represents a unique epitope for SUMO interaction spatially opposite to that observed for canonical SUMO interaction

Short proofs may be spacious : An optimal separation of space and length in resolution

A number of works have looked at the relationship between length and space of resolution proofs. A notorious question has been whether the existence of a short proof implies the existence of a proof that can be verified using limited space. In this paper we resolve the question by answering it negatively in the strongest possible way. We show that there are families of 6-CNF formulas of size n, fo

Drug Repurposing in Oncology : Current Evidence and Future Direction

BACKGROUND: Drug repurposing, the application of known drugs and compounds with a non-oncology primary purpose, might be an attractive strategy to offer more effective treatment options to patients with cancer at a low cost and reduced time.METHODS: This review described a total of 10 kinds of non-oncological drugs from more than 100 mechanical studies as well as evidence from population-based stu

The Health Returns of University Eligibility

This paper exploits an arbitrary university eligibility rule in Sweden combined with regression discontinuity to estimate the impact of university education on health derived demand for medical care. We find a clear jump in university attendance due to university eligibility of between 10 and 14 percentage points. For females this implies a 30-40% drop in self-harm. For males it coincides with red

Separation and Recycling of Functional Nanoparticles Using Reversible Boronate Ester and Boroxine Bonds

The sustainable and green chemistry concept calls for effective separation and recycling of valuable functional nanoparticles. In this work, a viable approach to separate and recover synthetic nanoparticles without involving heavy-duty instruments was established. The nanoparticle separation was enabled by using reversible boronate ester and boroxine bonds formed between boronic acid-functionalize

Silent timber build - modelling acoustic characteristics of timber structures

In year 2017 the WWN+ project "Silent Timber Build" is finishing. The project focused on studying timber structures with regard to their sound insulation characteristics, both airborne sound insulation and impact sound insulation. The aim is to develop calculation models (and / or to provide input to standardized models) for various timber structures available in Europe but also to facilitate futu

Development and implementation of a standardized care plan for carotid endarterectomy.

Carotid endarterectomy (CEA) is a standardized surgical procedure and is the third most common vascular surgical procedure in Sweden. To improve the quality of pre- and postoperative care for patients undergoing elective CEA, a standardized care plan (SCP) was developed and implemented during Spring of 2007 at a vascular clinic in Sweden. In order to spread light on obstacles and possibilities in

Robotics versus laparoscopy - an experimental study of the transfer effect in maiden users.

ABSTRACT: BACKGROUND: Robot-assisted laparoscopy (RL) is used in a wide range of operative interventions, but the advantage of this technique over conventional laparoscopy (CL) remains unclear. Studies comparing RL and CL are scarce. The present study was performed to test the hypothesis that maiden users master surgical tasks quicker with the robot-assisted laparoscopy technique than with the con

Application of first-order and Monte Carlo analysis in watershed water quality models

Functional analysis and Monte Carlo simulation were used to quantify uncertainties in model simulation of pollution behaviour and effects. The first-order part of the functional analysis method provides a measure of uncertainties in dependent variables in terms of uncertainties in independent variables. The procedure is based on first-order terms in the Taylor series expansion of the dependent var

Overcoming the fear of making a crappy sketch

This paper discusses which freehand drawing skills a designer needs in the 21st century and why not more people are using sketching as a creative tool. Are design schools teaching the adequate skills needed today? In the past 5-10 years focus has shifted from product design to experience design and the skills needed to make high end drawings might not be needed to the same extent. 3D computational

The zoonotic pathogen Borrelia afzelii in its natural hosts : Bacterial dissemination and immuno-transcriptomics

Most pathogens can infect a number of different host species, but host species often differ considerably in susceptibility to a given pathogen. In the case of zoonotic pathogens, natural hosts typically present little or no disease symptoms, while humans and other “spill-over” hosts often present severe symptoms. Differences in susceptibility do not only occur between natural and non-natural hosts