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The conventional indirect immunofluorescence assay for islet cell antibodies was compared with a two-colour immunofluorescent assay to detect both islet cell antibodies with fluorescein isothiocyanate-labeled rabbit anti-human IgG and pancreatic B cells with a monoclonal human proinsulin antibody and Texas red-labeled sheep anti-mouse IgG. Determinations of end-point titres showed a correlation be

Resource management in cloud computing is a difficult problem, as one is often tasked with balancing between adequate service to clients and cost minimization in dynamic environments of many interconnected components. To make correct decisions in these environments, good performance models are necessary. A common modeling methodology is to use networks of queues, but as these are prohibitively exp

Urea is a very attractive chemical raw material for large-scale production as it combines low cost with virtually unlimited supply and essentially no toxic effects. Here, we present a study on its use in the dehydration of trimethylolpropane with formation of 3-ethyl-3-(hydroxymethyl)oxetane. The reaction consists of carbonylation of trimethylolpropane and subsequent extrusion of carbon dioxide. T

Background: The ABILHAND questionnaire is recommended to assess perceived manual ability after stroke; however, more knowledge on interpretability is needed to improve the clinical applicability. Objectives: To determine clinically meaningful cutoff scores for different levels of perceived manual ability, assessed by ABILHAND, corresponding to established observed and perceived upper extremity ass

To promote sustainable manufacturing and lower industrial emissions, GE HealthCare is constantly assessing new approaches to improve their production processes. As a global manufacturer of contrast media, their potential for positive societal impact is significant. In addition to sustainability, a pharmaceutical production process is required to deliver products of high purity. This means that the

While an exit tax regime satisfies principles like fiscal sovereignty, fiscal territoriality, source and benefit as well as it can find justification in them at a national level, other conflicting issues arise. For instance, from the perspective of an individual, this can lead to double taxation when the Host State does not accept a step-up or deduction for the value on which taxes have already be

This thesis examines the Indonesian Government Regulation 25/24, which enables re-ligious organizations to obtain mining concessions, focusing on the socio-legal ten-sions, and power dynamics between the government, regulation, and religious organi-zations. The thesis’ primary purpose is to critically analyze how regulation that is pre-sented in neutral and technocratic language and can be utilize

This thesis explores the potential of vernacular architecture in contemporary design through the proposal of a community centre for Kitini Secondary School in Godawari, Nepal. The project is grounded in a site-specific, research-led design methodology, informed by fieldwork, material studies, and community engagement. It explores how traditional Nepali building practices, particularly the use of l

Reliable ankle torque measurements are important in rehabilitation, where strength assessments are used to evaluate recovery and guide treatment. Isokinetic dynamometers, such as the Biodex system, are commonly used to provide controlled measurements of joint torque. However, these measurements rely on the ankle being held in a stable and reproducible position. Mechanical play in the ankle-attachm

This thesis investigates how the right-wing populist German Party Alternative für Deutschland (AfD) presented and framed German development cooperation on the social media platform Facebook during the 20th legislative period (2021-2025). Over the last decades, social media has become an increasingly important tool of political communication and information source for the public. Thus, this study a

AIMS: Vascular atherosclerotic calcification is a pathological process marked by the abnormal deposition of calcium minerals in the intima. Asporin (ASPN) is a small leucine-rich proteoglycan which interacts with collagen and calcium. Due to its role in matrix mineralization, we hypothesized that ASPN might act as a regulator of vascular calcification, thereby promoting atherosclerotic plaque stab

The world has encountered numerous global crises, including epidemics, military conflicts, and economic collapse. Innovative digital technologies, such as Industry 4.0 (I4.0), can undoubtedly help improve industries’ operations during critical times. The dairy industry has seen an increment in technological adoption in the last few years. Adopting cutting-edge technologies is regarded as more feas

This study provides an in-depth analysis of the impact of a multimodal journey-planning app on users of informal public transport systems in Cochabamba, Bolivia. We analyze survey data (N=648) collected through the Trufi Association NGO's digital travel app on changes in mobility behavior, satisfaction, and everyday life improvements. Participants report more frequent use of informal transport (49

Abstract: Perfusion MRI techniques—including dynamic susceptibility contrast (DSC) MRI, dynamic contrast-enhanced (DCE) MRI, arterial spin labeling (ASL) MRI, and intravoxel incoherent motion (IVIM) MRI—hold strong potential as imaging techniques for diagnosing, staging, and monitoring disease across a range of clinical applications. However, clinical adoption, especially of quantitative parameter