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Effect of dronedarone vs. placebo on atrial fibrillation progression : a post hoc analysis from ATHENA trial

AIMS: This post hoc analysis of the ATHENA trial (NCT00174785) assessed the effect of dronedarone on the estimated burden of atrial fibrillation (AF)/atrial flutter (AFL) progression to presumed permanent AF/AFL, and regression to sinus rhythm (SR), compared with placebo. METHODS AND RESULTS: The burden of AF/AFL was estimated by a modified Rosendaal method using available electrocardiograms (ECG)

Mortality not increased in patients with non-functional adrenal adenomas : a matched cohort study

CONTEXT: Mild autonomous cortisol secretion (MACS) is associated with increased mortality in patients with adrenal incidentalomas (AI), but little is known regarding the potential risk associated with non-functional adrenal adenomas (NFAA), which constitute the majority of AI.OBJECTIVE: Compare mortality risk in patients with NFAA, and different levels of MACS, to matched controls.METHOD: This was

Online remote behavioural intervention for tics in 9- to 17-year-olds : the ORBIT RCT with embedded process and economic evaluation

BACKGROUND: Behavioural therapy for tics is difficult to access, and little is known about its effectiveness when delivered online.OBJECTIVE: To investigate the clinical and cost-effectiveness of an online-delivered, therapist- and parent-supported therapy for young people with tic disorders.DESIGN: Single-blind, parallel-group, randomised controlled trial, with 3-month (primary end point) and 6-m

Conclusion : Towards a ‘Deep Debate’ on the Anthropocene

In this edited volume, we explored the contributions that political science as a discipline can offer to the evolving Anthropocene debate. The term Anthropocene denotes a new geological epoch in the Earth’s history in which humans have become the main drivers of planetary-wide changes. Some authors interpret this as good news, pointing to progress as a result of human ingenuity and the endless pos

Introduction : A Political Science Perspective on the Anthropocene

Over the past decades, it has become more and more obvious that ongoing globalisation processes have substantial impacts on the natural environment. Studies reveal that intensified global economic relations have caused or accelerated dramatic changes in the Earth system, defined as the sum of our planet’s interacting physical, chemical, biological and human processes (Schellnhuber et al. 2004). Cl

Clinical applications of heart rhythm monitoring tools in symptomatic patients and for screening in high-risk groups

Recent technological advances have facilitated and diversified the options available for the diagnosis of cardiac arrhythmias. Ranging from simple resting or exercise electrocardiograms to more sophisticated and expensive smartphones and implantable cardiac monitors. These tests and devices may be used for varying periods of time depending on symptom frequency. The choice of the most appropriate h

Injustice in Urban Sustainability : Ten Core Drivers

This book uses a unique typology of ten core drivers of injustice to explore and question common assumptions around what urban sustainability means, how it can be implemented, and how it is manifested in or driven by urban interventions that hinge on claims of sustainability.Aligned with critical environmental justice studies, the book highlights the contradictions of urban sustainability in relat

Waves of media democratization: A brief history of contemporary participatory practices in the media sphere

The article aims to provide a more historically grounded approach to the relationship between communication and participation, by distinguishing different waves of media democratization. The article first discusses the concept of participation and some of its complexities, and then sketches a series of intense moments of participation in and through the media in (mainly the second half) the 20th a

Overextension in Verb Conjunctions

Hampton (1988) discovered that people are subject to overextension they categorize some things as falling under a conjunction (e.g., they categorize chess as a sport which is also a game) but not as falling under both of the corresponding conjuncts they do not categorize chess as a sport). Although subsequent literature has replicated this effect with a wider range of constructions than those orig

Patients with chronic obstructive pulmonary disease and chronically colonized with Haemophilus influenzae during stable disease phase have increased airway inflammation.

Some patients with chronic obstructive pulmonary disease (COPD) show increased airway inflammation and bacterial colonization during stable phase. The aim of this study was to follow COPD patients and investigate chronic colonization with pathogenic bacteria during stable disease phase, and relate these findings to clinical parameters, inflammatory pattern, lung function, and exacerbations.

A simplified preservation method for lungs donated after cardiac death.

The shortage of donor lungs restricts the number of lung transplantations that can be performed. However, extension of the donor pool using organs donated after cardiac death (DCD) could potentially increase the number of patients who undergo transplantation. To establish acceptance among hospital personnel and the donor's next of kin for the uncontrolled DCD procedure we proposed a simplified pre

Comparing Nations - Perceptions of Global Risk and Environmental Concern

The intention of this chapter is neither a pure methodological nor a theoretical discussion, but instead, an empirical analysis which aims to understand variations in perceptions of global risks and environmental concern in a number of countries. The discussion, however, relies on methodological as well as theoretical perspectives concerning the shortcomings and pitfalls one encounters in comparin