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Cognitive-behavioral therapy (CBT) with exposure and response prevention is the most empirically supported psychological treatment for obsessive–compulsive disorder (OCD). Healthcare organizations and practice guidelines recommending CBT for OCD typically rely on meta-analyses that usefully aggregate treatment outcome findings. However, a critical methodological aspect of meta-analyses is the pote
INTRODUCTION: Hospital-acquired bloodstream infections (HA-BSIs) are severe and require antibiotic therapy. In non-complicated BSIs, shortened therapy reduces side effects without compromising efficacy. The impact of shortened antibiotic therapy in HA-BSI critically ill patients without indication of prolonged therapy requires further evaluation. METHODS: Using the international prospective EUROBA
The objective of this investigation was to explore a hybrid application of Structural Equation Modelling (SEM) and Fuzzy-set Qualitative Comparative Analysis (FsQCA) to assess the impact of safety-related behavioural traits on the performance of bicyclists using a limited sample of data as a case study. These behavioural characteristics of cyclists are fundamental when specific cyclist groups are
Two major debates frame Arctic prehistory: the emergence of specialized maritime economies that support sedentism and growing socio-political complexity, and the role of these economies in the transition from Paleo-Inuit to Neo-Inuit traditions. This shift, originating in the Bering Strait, led to Thule Inuit dispersal across the Arctic, impacting Indigenous communities today. However, understandi
Background: We investigated the impact of time to adjuvant chemotherapy (AC) on survival after surgical resection (<8 weeks or 8–16 weeks) for patients with non-small cell lung cancer (NSCLC) by applying a target-trial emulation. Material and Methods: We used Swedish population-based healthcare registries to emulate a hypothetical target trial, with treatment arms of ‘initiate AC <8 weeks postoper
BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy variant carriers in a multiancestry US population and examine the risk of adverse clinical outcomes. METHODS: This retrospective cohort study included multiancestry US adults aged ≥18 years with sequencing data from the All of Us Research Program. Pathogenic/likely pathogenic variants in cardiomy
An integrated framework is introduced and applied to assess the health impact of airborne pollution with greater physiological relevance, moving beyond conventional exposure metrics. Measured particle number size distribution data was integrated with a regional respiratory tract deposition fractions to estimate total and alveolar deposited particle surface area concentrations. Land use regression
BACKGROUND: Drug-coated devices are frequently used in coronary and peripheral interventions, but their effect on amputation risk in peripheral artery disease is unclear. We assessed whether drug-coated devices affect the rate of above-ankle amputation in patients with chronic limb-threatening ischaemia undergoing infrainguinal endovascular revascularisation.METHODS: The Swedish Drug-Elution Trial
Hydrolysis rate constants of sludge at 35°C, 55°C, and 60°C were found to be 0.32 d-1, 0.44 d-1, and 0.50 d-1, respectively in pilot-scale experiments with digestion of municipal sludge in semi-continuously operated reactors. The hydrolysis rate constants as well as estimated chemical oxygen demand (COD) fractions in the feed were implemented in a mathematical model for anaerobic digestion similar
Anaerobic digestion would enable the energy potential of agricultural crop residues such as ley crops, sugar beet tops and straw to be harnessed in Sweden. These residues are so spread out that full utilisation of the potential by centralised slurry-based technology is difficult, its appearing that simple but effective high-solids reactor systems have a better chance of being economically viable o
The aim of this study is to examine the relationship between retailer brand (RB) market shares and consumer prices. Furthermore it investigates whether changes in category price and expenditure are due to changes in customer purchase patterns or changes in relative price levels (price gap) of RBs and national brands (NBs). Data from the market research company GfK's consumer household panel, compr
The paper treats encounters between Swedes and Germans within the framework of lodges and secret societies in Swedish-Pomerania during the 1760-ies.
SchemaMVEN16_HT15_26okt15 SCHEMA 2015-10-26 Schema för MVEN16: Klimatpolitik, samhällsstyrning och kommunikation, 15 hp, Ht 15 Kurstid: 2015-11-02 – 2016-01-15 Kursansvarig: Roger Hildingsson, roger.hildingsson@svet.lu.se Introduktion: 2015-11-02, kl. 11.00 (OBS! Vi startar prick kl. 11.00!) Lärare: CD: Carl Dalhammar, IIIEE, carl.dalhammar@iiiee.lu.se JAO: Johanna Alkan Olsson, CEC, johanna.alkan
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schemamven16_ht15_v1.pdf - 2026-07-01
BACKGROUND: The REC-CAGEFREE trial showed that drug-coated balloons (DCB) did not achieve non-inferiority in the treatment of non-complex de novo lesion compared to a strategy of drug-eluting stents (DES). However, a prespecified subgroup analysis of arteries sized <3.0 mm revealed no difference in the device-oriented outcome compared to DES. The aim of present study was to validate that finding i
Background: Prescribing of antibiotics for common infections varies widely, and there is no medical explanation. Systematic reviews have highlighted factors that may influence antibiotic prescribing and that this is a complex process. It is unclear how factors interact and how the primary care organization affects diagnostic procedures and antibiotic prescribing. Therefore, we sought to explore an
A method of separately quantifying organic and inorganic 14C compounds present in spent ion-exchange resins and process water from nuclear power reactors has been developed. Extraction of carbon compounds is accomplished by means of acid stripping (inorganic 14C) and subsequent wet oxidation (organic 14C) or by N2 purging in combination with a catalytic furnace (oxidized and reduced gaseous compou
ATP and ADP inhibit, in varying degrees, several dehydrogenases of the central carbon metabolism of Lactococcus lactis ATCC 19435 in vitro, i.e. glyceraldehyde-3-phosphate dehydrogenase (GAPDH), lactate dehydrogenase (LDH) and alcohol dehydrogenase (ADH). Here we demonstrate mixed inhibition for GAPDH and competitive inhibition for LDH and ADH by adenine nucleotides in single inhibition studies. T
The resistance of human immunodeficiency virus type 1 (HIV-1) to antibody-mediated immunity often prevents the detection of antibodies that neutralize primary isolates of HIV-1. However, conventional assays for antibody functions other than neutralization are suboptimal. Current methods for measuring the killing of virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC) are li
