Filtyp
Concrete is the most commonly used material worldwide, often associated with an irreversible production process and waste generation at the end-of-life. As such, the concrete industry holds large untapped potentials for moving towards more circular economy (CE) practices. Product service system (PSS) offerings incentivize CE through extending product use, improving product performance and developi
We present a systematic study on the interaction potential of lamotrigine, with focus on psychoactive drugs. A review of routine serum concentration measurements of lamotrigine performed in our laboratory yielded a total of 1733 serum samples from 829 patients (530 women, 299 men) suitable for statistical analysis. Main results for the whole study population were (median; interquartile range in pa
Prel. schema MVEN18 - Klimatstrategiska metoder Vårterminen 2021 Kurstid: 24 mar – 6 jun, 2021 Kurschef: Niklas Vareman Lärare: CW Christine Wamsler HT Henrik Tehler HH Henrik Hassel DP Dmytro Perepolkin NV Niklas Vareman AO Adelina Osmani JJ Jonas Johansson JMP Jurate Miliute-Plepiene AP Andrius Plepys Salar: Distansundervisning Litteratur: Wamsler, C., (2013). Cities, disaster risk and adaptatio
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2021-02/Schema_MVEN18_vt_21.pdf - 2026-06-30
https://www.botan.lu.se/flower-power-day-botan - 2026-07-01
Most drugs act on biomacromolecules. The Cost of developing new drugs is very high. A method to accurately predict binding affinities would be very useful. We have studied molecular mechanics with generalised Born and surface--area solvation (MM/GBSA) and alchemical free energy perturbation methods (FEP) for use in calculations of ligand binding energies. For the MM/GBSA method we have tested: Ca
Popular Abstract in Swedish Grupp B streptokocker (GBS; Streptococcus agalactiae) är den vanligaste orsaken till livs-hotande infektioner hos nyfödda barn. Enbart i USA orsakar GBS ~10 000 fall av meningit (hjärnhinneinflammation), pneumoni (lunginflammation) och sepsis (blodförgiftning) varje år. Infektionerna har hög dödlighet och en stor del av de barn som överlever infektionerna får bestående Streptococcus pyogenes (group A streptococcus) and the group B streptococcus (GBS) are two important human pathogens that cause different types of diseases and express different surface structures implicated in virulence. This thesis focuses on several surface proteins expressed by these pathogens, analyzing the biological function of these proteins and their ability to elicit protective immunity.
Integration of machine learning (ML) components in critical applications introduces novel challenges for software certification and verification. New safety standards and technical guidelines are under development to support the safety of ML-based systems, e.g., ISO 21448 SOTIF for the automotive domain and the Assurance of Machine Learning for use in Autonomous Systems (AMLAS) framework. SOTIF an
