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Background Mental health interventions should demonstrate an effect on patients' functioning as well as his/her needs, in particular on unmet needs whose assessment depends on the perspective of either the patient or the clinician. However, individual met and unmet needs appear to change over time, qualitatively and quantitatively, raising questions about their sensitivity to change and about the

Insulin secretion is controlled by the beta cell's metabolic state, and the ability of the secretory granules to undergo exocytosis increases during glucose stimulation in a membrane potential-independent fashion. Here, we demonstrate that exocytosis of insulin-containing secretory granules depends on phosphatidylinositol 4-kinase (PI 4-kinase) activity and that inhibition of this enzyme suppresse

The frequent mounting and dismounting the tractor required by many farming operations increases the risk of falls, particularly for older farmers. The present study explored the risk factors related to tractor ingress and egress in older farmers from two countries with a different tradition in terms of safety culture: Sweden and Italy. Eighteen male farmers aged 65 + (8 from Skåne region, southern

Background: Dialectical behavior therapy (DBT) is an evidence-based treatment for self-harm and emotion regulation difficulties. A modified version, DBT-Skills System (DBT-SS), has been developed in the USA for individuals with cognitive difficulties. The present study is a pilot study, testing the DBT-SS in a Swedish context.Methods: Six participants were treated with individual therapy and group

Urbanisation is proceeding at an alarming rate which forces wildlife to either retreat from urban areas or cope with novel stressors linked to human presence and activities. For example, urban stressors like anthropogenic noise, artificial light at night and chemical pollution can have severe impacts on the physiology of wildlife (and humans), in particular the immune system and antioxidant defenc

The market for ready-to eat vegetables is increasing, but unfortunately so do the numbers of food-borne illness outbreaks related to these products. A previous study has identified bacterial strains suitable for biocontrol of leafy green vegetables to reduce the exposure to pathogens in these products. As a tentative safety evaluation, five selected strains (Rhodococcus cerastii MR5x, Bacillus coa

The existence of impartial and independent courts is a cornerstone of the success of the European project. The recent renaissance of “illiberal States” jeopardises the application of the rule of law and risks destroying the foundations of the EU legal order. In 2018, the Court of Justice of the European Union (CJEU) began developing two new lines of case-law. Firstly, the CJEU found itself to be c

MHC genes are extraordinarily polymorphic in most taxa. Host-pathogen coevolution driven by negative frequency-dependent selection (NFDS) is one of the main hypotheses for the maintenance of such immunogenetic variation. Here, we test a critical but rarely tested assumption of this hypothesis—that MHC alleles affect resistance/susceptibility to a pathogen in a strain-specific way, that is, there i

Introduction: In Sweden, head computed tomography (CT) is commonly used for prediction of neurological outcome after cardiac arrest, as recommended by guidelines. We compare the prognostic ability and interrater variability of routine and novel CT methods for prediction of poor outcome. Methods: Retrospective study including patients from Swedish sites within the Target Temperature Management afte

This paper addresses Test Application Time (TAT) reduction for core-based 3D Stacked ICs (SICs). Applying traditional test scheduling methods used for non-stacked chip testing where the same test schedule is applied both at wafer test and at final test to SICs, leads to unnecessarily high TAT. This is because the final test of 3D-SICs includes the testing of all the stacked chips. A key challenge

Doktorsavhandlingen ger inblick i en betydelsefull konsekrerande beslutsprocess inom det svenska konstfältet under perioden 1885–1920. Den analyserar de sociala strukturer som bar fram Nationalmuseums inköpsnämnds och museinämnds årliga beslutsförslag till Kungl. Maj:t om vilka oljemålningar, skapade av vid tiden levande svenska konstnärer, som skulle inlemmas i samlingarna och vilka som skulle exThis dissertation examines the Swedish National Museum of Fine Arts (Nationalmuseum) as a consecrating institution of fine art, between 1885 and 1920. A time influenced by major events such as the First World War, Sweden’s industrial revolution and the advent of universal suffrage. During this period, the production and consumption of the Arts was characterised by rivalry between three fractions,

Background: The CREST model is a prediction model, quantitating the risk of circulatory-etiology death (CED) after cardiac arrest based on variables available at hospital admission, and intend to guide the triage of comatose patients without ST-segment-elevation myocardial infarction after successful cardiopulmonary resuscitation. This study assessed performance of the CREST model in the Target Te

Nowadays, organizations pursue their aims in a context of distributed collaboration, creating a need not only for supporting ICT systems, but for a hu-man-centred focus in which individual and group sense-making and learning are supported by appropriate toolsets. We argue that development of such toolsets re-quires an open systems approach. This paper discusses one example: non-competitive benchma

Detta examensarbete rör direktiv 2006/46/EG och dess överensstämmelse med den europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna. Examensarbetet använder Sverige som ett exempel, och analyserar främst lagen (2003:389) om elektronisk kommunikation och dess tillkortakommanden vad gäller brottsbekämpande myndigheters tillgång till lagrade trafikuppgifter. This thesis concerns Directive 2006/46/EC and its compliance with the European Convention on Human Rights and Fundamental Freedoms. The thesis uses Sweden as an example, and mainly analyses the shortcomings in Swedish legislation on how traffic data may be accessed by law enforcement authorities, finding that the regulations under the Swedish Electronic Communications Act breaches Article 8 and 13

Earlier treatment of breast cancer results in better survival. Screening enables this through detection of tumors before they cause symptoms. On the negative side, some tumors if not detected through screening would not cause symptoms, leading to overdiagnosis. Improvements in image quality allow even earlier detection and diagnosis of even smaller tumors at an even earlier stage. This study aims

Oath-taking during Roman Antiquity constitutes a telling example of how words and matter interplay and relate to one another. Ancient Latin literature provides a myriad of representations of oaths sworn, both fictive and supposedly historical, where matter somehow figure in the procedure. In this study, a selection of personal oaths from Roman literature are explored in terms of materiality and ag

Seismic Structural Health Monitoring (S2HM) provides information about the integrity of civil structures and infrastructure in the aftermath of an earthquake. However, quantifying the benefits of S2HM information is crucial to justify the investment in S2HM systems. The benefit of S2HM can be computed through the Value of Information (VoI) from Bayesian decision theory, which compares the expected