Sökresultat

Studies were conducted to elucidate co-receptor spectrum and function of the inflammatory receptor, CMKLR1/ChemR23, which was recently identified as the receptor for the cystatin-like chemoattractant, TIG2, also named chemerin. An infection model was applied based on stably transfiected NP-2.CD4 host cells expressing various co-receptor constructs and exposed to panels of HIV-1, HIV-2 and SIV prim

Aim This paper presents a probabilistic method for the characterization of pollen taxa using attributes, and for the reconstitution of past biomes. The probabilities are calculated on the basis of European floristic and pollen databases sufficiently large and exhaustive to provide robust estimates. Location The analysis is based on data from approximately 1000 sites throughout Europe. Method We us

This thesis has investigated the prevailing understanding of poor leadership as a major impediment to the democratization of the Democratic Republic of Congo. Analytical studies found evidences on the correlation between the authoritarian regimes installed in the Democratic Republic of Congo and the abortive process of democratization under the leadership of Mobutu Sese Seko and Laurent-Désiré Kab

Introduction Osteoarthritis (OA) is the most common form of arthritis and a leading cause of disability worldwide. Metabolic comorbidities such as type II diabetes occur with a higher rate in people with OA than in the general population. Several factors including obesity, hyperglycaemia toxicity and physical inactivity have been suggested as potential links between diabetes and OA, and have been

Pulmonary arterial hypertension (PAH) is a rare disease that affects the pulmonary vasculature. Characterized by increased pulmonary arterial pressures and vascular resistance, it causes right heart failure (HF), and premature death. The main symptom, exertional dyspnoea, is non-specific where patient’s and doctor’s delay often lead to diagnosis in advanced stages. Despite development of PAH speci

Problem Description: Entering a new business segment introduces numerous challenges for a high-tech company. New product development processes, even when well-managed, have a high expected failure rate and commercialisation is costly. High-tech markets are volatile, fast-moving and uncertain with a short window of opportunity for introducing and establishing new products. Strategy research does no

This study aimed to explore the effect of group conversation about injustice using methods from Acceptance and Commitment Training (ACTr) in a theatre setting. The objective was to reduce prejudice, psychological inflexibility with stigma and white fragility as well as increase compassion and behavioural intentions towards equality, among a sample of Swedish adults. An interactive conversational t

Disasters exacerbate pre-existing gender inequalities, rendering women vulnerable to various forms of harm. Nevertheless, women are not victims to be protected by men; rather, they play a significant role in post-disaster recovery. Previous studies in Türkiye’s context revealed a lack of gender lens in disaster response and management. This thesis investigates the gendered experiences of women in

The Amazon has always been a strategic region because of its rich variety in natural resources. Its global interest is spreading across levels and scales, influenced by the increasing demand for fossil fuels and biodiesel and the threat of climate change. Neoliberal practices continue privatizing and exploiting the Amazon´s resources regardless the Indigenous communities’ interests. These communit

Invasion, mass warfare, foreign hordes, slaughter and pure evil. When pondering these words one will usually attribute them to the traditional conception of the barbarian, and not to something as seemingly distant as Western civilization. In this paper I aim to discuss the rare combination of liberal European civilization and its relation with barbarism in general, specifically focusing on the ca

Space activity is rapidly developing, increasing globally in public and private sectors, and subject to competition amongst dominant spacefaring actors. Global space governance is discordant with the contemporary environment motivating international efforts to develop it. Since 2021 the European Union (EU) is intensively developing space policy and strategies. This dissertation contributes to stud

The advent of new technologies for single-cell RNA sequencing analyses has resulted in the discovery that the myeloid compartment in the tumor microenvironment (TME) is far more complex than previously appreciated, and that intrinsic and extrinsic factors in the TME highly influence the immunosuppressive or active states of these cell types. There is now a need to develop multiplex assays to ident

Detta examensarbete ger ett förslag på en ny järnvägsstation i Kirunas nya centrum. I Kiruna pågår just nu en stadsomvandling, där en tredjedel av staden flyttas tre kilometer österut på grund av markdeformationer från Kirunagruvan. Detta innebär stora förändringar för Kirunaborna men även stora förändringar i stadsbilden, då majoriteten av centrum har eller kommer rivas och byggas upp igen i nya This thesis gives a suggestion for a new railway station in the new city center of Kiruna, Sweden. Kiruna is now experiencing an urban transformation, where one third of the population and the city moves three kilometers to the east due to ground deformations coming from the Kiruna iron ore mine. This leads to huge changes for Kiruna’s population, but also huge changes in the cityscape, since most

I föreliggande examensarbete har en riskanalysbaserad metod utvecklats som medger bedömning av fiskfaunas respons till ett förändrat framtida klimat såsom modellerat av IPCC, här kallat klimatinducerat påverkanstryck. Metoden har använts på två fiskarter, röding och siklöja, inom deras utbredningsområde i Jönköpings län. Fiskarterna valdes primärt för att de är kallvattenarter och förutspås vara m

This thesis investigates the main obstacles preventing PLWHA in Jamaica from accessing treatment. Currently the number of PLWHA accessing treatment in Jamaica is lower than would be expected. This research utilises qualitative data collection methods in order to canvass the views of a broad range of individuals involved in the fight against HIV in Jamaica. These include PLWHA, NGO workers, Civil

This thesis explores the increased electricity access between 2003 and 2019 in Afghanistan by employing two main explanatory variables – solar power and international involvement. The models are based on logistic regressions, investigating urban and rural areas, as well as a sample of the whole population. The data is survey data collected annually, by the Asia Foundation, throughout the country.