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The neural correspondence between the systems responsible for the execution and recognition of actions has been suggested both in humans and non-human primates. Apart from being a key region of this visuo-motor observation-execution matching (OEM) system, the human inferior frontal gyrus (IFG) is also important for speech production. The functional overlap of visuo-motor OEM and speech, together w
Androgen deprivation therapy (ADT) is first-line treatment for metastatic prostate cancer (PCa). Gonadotrophin-releasing hormone (GnRH) agonists are the most commonly used ADT but have several theoretical physiologic disadvantages (e.g. initial testosterone surge, potential microsurges upon repeat administration). Testosterone surge delays the intended serologic endpoint of testosterone suppressio
Scholarly discourses on energy security have developed in response to initially separate policy agendas such as supply of fuels for armies and transportation, uninterrupted provision of electricity, and ensuring market and investment effectiveness. As a result three distinct perspectives on energy security have emerged: the `sovereignty' perspective with its roots in political science; the `robust
In this work, we report for the first time the rotational coherent anti-Stokes Raman spectroscopy (CARS) spectrum of water vapor, recorded through experiments at 400K and 670K for Raman shifts up to 600cm(-1). Using the standard dual-broadband pure rotational CARS approach, the resonant structure was overwhelmed by a strong non-resonant background. By employing a polarization technique, this backg
In this study we describe a novel flow-through respirometer with automated and semi-continuous detection of key water variables. The recirculating aquaculture system was designed to house aquatic organisms in culture-like conditions and allow long-term, high-precision measurements. Nine respirometry tanks (250 L in volume each) housed animals, and a tenth (without animals) acted as a reference tan
Liquid cooling incorporating microchannels are used to cool electronic chips in order to remove more heat load. However, such microchannels are often designed to be straight with rectangular cross section. In this paper, on the basis of straight microchannels having rectangular cross section (SRC), longitudinal-wavy microchannel (LWC), and transversal microchannel (TWC) were designed, respectively
Inhaled therapies are central to the treatment of asthma and chronic obstructive pulmonary disease. Physicians consider many factors when selecting the most appropriate inhaler device, including device efficacy and the cost to the health care system. This review aims to discuss the factors that are important when considering inhaler devices and the importance of continuity in the choice of inhaler
Objective: This randomized methodologic study sought to test the reliability of an Internet questionnaire and investigate the differences in response rates between traditional pen-and-paper questionnaires and Internet questionnaires for measuring patient-reported outcome after total hip replacement surgery. Methods: From the Swedish Hip Arthroplasty Register, 2400 patients were chosen at random bu
Here we present the 100% complete assignment chemical shift of non-labile H-1, N-15 and C-13 nuclei of Calbindin D-9k P43G. The assignment includes all non-exchangeable side chain nuclei, including ones that are rarely reported, such as LysN zeta as well as the termini. NMR experiments required to achieve truly complete assignments are discussed. To the best of our knowledge our assignments for Ca
Histomorphometry is commonly applied to study bone remodeling. Histological definitions of cortical bone boundaries have not been consistent. In this study, new criteria for specific definition of the transitional zone between the cortical and cancellous bone in the femoral neck were developed. The intra- and inter-observer reproducibility of this method was determined by quantitative histomorphom
The mineral dust cycle responds to climate variations and plays an important role in the climate system by affecting the radiative balance of the atmosphere and modifying biogeochemistry. Polar ice cores provide unique information about deposition of aeolian dust particles transported over long distances. These cores are a palaeoclimate proxy archive of climate variability thousands of years ago.
This review describes the use of Pickering emulsions for topical drug delivery. The focus is on Pickering emulsions and how to formulate these. However, a short description of the challenges of topical drug delivery is also given. The article describes how Pickering emulsions might have other properties than traditional topical creams. It is our believe that Pickering emulsions could give added va
The empirical part of this study is based on a survey of 600 Swedish households and a number of interviews where questions about residential energy behaviour and possible policy instruments for change were raised. The study provides insight into current behavioural patterns and gives a bottom-up perspective on the realistic perspective potentials for change and ways to achieve them. Residential en
The ability to compare soil chemical data achieved by different chemical extraction methods is a necessity for an efficient long-term monitoring of soils and for comparisons of results from regional soil surveys with differing standard methods. This study compares two common, methods for analysis of soil chemical properties, the combination of soil extraction in 1.0 M NH4Cl and 1.0 M KCl and the s
The lack of a conserved tyrosine autophosphorylation site is a unique feature of the C-terminal Src-kinase, Csk, although this protein tyrosine kinase can be autophosphorylated on tyrosine residues in vitro and in bacteria. Here we show that human Csk is tyrosine phosphorylated in HeLa cells treated with sodium pervanadate. Phosphorylation in vivo occurs mainly at Tyr-184 and in vitro mainly at Ty
Randomized, double-blind, controlled studies have shown that treatment with risedronate reduces the risk of vertebral fracture in postmenopausal women with established vertebral osteoporosis. They also show that the drug decreases the risk of non-vertebral fractures in women with osteoporosis. The aim of this study was to investigate the cost-effectiveness of risedronate in postmenopausal women wi
Popular Abstract in Swedish Avloppsvatten renas från fosfor för att minimera utsläppet till sjöar och hav. Näringsämnena fosfor och kväve bidrar till övergödningen i våra vatten och kan reduceras kraftigt på avloppsreningsverken. Fosforavskiljning går huvudsakligen ut på att få löst fosfat att hamna i en fast fas ? slammet, för att sedan kunna avskilja det från det renade vattnet. Bakterier som vThe idea of phosphorus removal at wastewater treatment plants is to transfer dissolved phosphorus into a solid phase. Together with the rest of the produced sludge it is then removed from the water, resulting in a decreased concentration of phosphorus in the effluent and the prevention of the eutrophication in the recipient. Phosphorus can either be stored biologically, with enhanced biological p
New radiative lifetimes for 20 levels of Pr II have been measured using the time-resolved laser-induced fluorescence (LIF) technique. The combination of these experimental values with theoretical branching fractions (BF) obtained with the pseudo-relativistic Hartree-Fock (HFR) approach has allowed us to determine oscillator strengths and transition probabilities for about 150 lines appearing in th
The aim of this study was to determine the threshold of fracture probability at which interventions became cost-effective in men and women, based on data from Sweden. We modeled the effects of a treatment costing $500 per year given for 5 years that decreased the risk of all osteoporotic fractures by 35% followed by a waning of effect for a further 5 years. Sensitivity analyses included a range of
