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α-Synuclein (α-syn), a small protein that has the intrinsic propensity to aggregate, is implicated in several neurodegenerative diseases including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), which are collectively known as synucleinopathies. Genetic, pathological, biochemical, and animal modeling studies provided compelling evidence that α-syn aggr
Human papillomavirus (HPV) infection is a necessary factor in the cervical cancer development. Also after treatment for cervical dysplasia, HPV can be present and promote the recurrence of cervical disease. In the present study, the aim was to perform a long-term follow-up on the ability of HPV testing with genotyping, as compared with cytology, to predict recurrence of high-grade cervical intraep
The aim of this study was to estimate rates and type of definitive surgical interventions for nephrolithiasis in Swedish patients with ankylosing spondylitis (AS) compared to the general population.
Out of the 14 agnostoid species/subspecies so far recorded from the Furongian of Scandinavia, seven are excellent biostratigraphical indices and important for correlation between Baltica and other palaeocontinents. Glyptagnostus reticulatus, Aspidagnostus lunulosus and Agnostus (Homagnostus) obesus first appear at the base of the G. reticulatus Zone, allowing a precise correlation of the base of t
Amino-functional benzoxazine monomers have been successfully prepared. Several routes have been applied to incorporate amino group into benzoxazine structure. These approaches include reduction of the corresponding nitro-functional benzoxazines and deprotection of protected amino-functional benzoxazine monomers. Various approaches that allow primary amine groups to be prepared without damaging the
An M-BCJR algorithm is proposed and tested over an AWGN channel with moderate to very intense intersymbol interference (ISI). Two M-BCJR applications are evaluated, simple detection over the ISI channel and turbo equalization. The signaling is binary faster than Nyquist linear modulation. The ISI models tested correspond to transmission of increasingly many bits/Hz-s with a fixed signal spectra; t
In the era of proteomics, glycomics and ultimately metabolomics, with constantly increasing knowledge regarding the human biosystem, the number of specialized therapeutic agents which will be developed against different diseases is predicted to be on the upswing. An increasing portion of these new drugs will, according to recent predictions (Labrou, 2003), be of proteinaceous origin produced accor
Popular Abstract in Swedish Katalys är en nyckelteknik inom kemisk industri och spelar en förvånansvärt viktig roll i vårt moderna samhälle. Många av de produkter och kemikalier som används i vårt dagliga liv produceras faktiskt med hjälp av katalysatorer. En annan mycket viktig tillämpning är att avlägsna giftiga ämnen från fordonsavgaser. Det mest fantastiska är att en katalysator snabbar på ochThis PhD thesis reports on investigations of the atomic scale structure of model catalysts relevant for the catalytic oxidation of CO and methane over Pd, and NOx reduction over silver-alumina, important reactions in automotive catalysts. By using complementary experimental techniques such as X-ray Photoelectron Spectroscopy, High Pressure X-ray Photoelectron Spectroscopy, Surface X-ray Diffractio
In communication systems, all service control nodes, such as for example Web sites or mobile switching centers, can be modeled as a server system with one or more servers processing the incoming requests. To avoid overload at the service node some type of admission control mechanism is usually implemented to guarantee good performance also during high traffic loads. In this paper we investigate, f
The electrical output of low concentration systems with standard pv cells is heavily impaired by non uniform irradiation distribution on the cells. In order to design new concentrators that improve the system efficiency by homogenizing the light, a new method of evaluation has been developed. It is based on simulations, and generates an estimated annual output. The method consists of three steps,
Popular Abstract in Swedish Vibrationsskador i händerna utgör idag ett stort yrkesmedicinskt problem. Långvarig exponering av handhållna vibrerande verktyg kan leda till ett hand-arm vibrationssyndrom (HAVS) som är en kronisk åkomma. Vibrationsskadan kan vara irreversibel och är progressiv om vibrationsexponeringen fortsätter. Många arbetare utsätts dagligen för hand-arm vibrationer. Elva procent Workers exposed to hand-held vibrating machines may risk developing a hand-arm vibration syndrome (HAVS), a condition which can cause chronic impairment and disability. The aims of this thesis were 1) to obtain deeper insight and further knowledge of HAVS and the consequences for hand function, and aspects of quality of life (QoL); 2) to investigate the usefulness of clinical assessments in diagno
The dissertation is written within the project Strengthening Legal Education in Vietnam.
Vehicular ad-hoc networks (VANETs) offer a large number of new potential applications. One of the envisioned applications is of course Internet access, which can be provided with the help of some roadside basestations. Many of the applications benefit from multi-hop relaying of information, thus requiring a routing protocol. Characteristics unique to VANETs (such as high mobility and the need for
