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Soch-infoblad-2016-10-28

Prefekten informerar • Ny medarbetare. Karl Eriksson har antagits till forskarutbildningen och börjar sin doktorandanställning jan 2017. Välkommen! • Skyddsombud. Tina Mattsson är vårt nya skyddsombud. Skyddsombudet har en viktig funktion i institutionens systematiska arbetsmiljöarbete och det faktum att vi är inne i en ombyggnadsprocess och ganska snart måste börja planera för en flytt gör funkti

https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/soch-infoblad-2016-10-28.pdf - 2026-05-14

Supercritical fluid chromatography and two-dimensional liquid chromatography : From new applications to technical innovations

Lignin depolymerisation can be utilized to produce value-added aromatic compounds. One of the major challenges in lignin depolymerisation study is the development of effective analytical tools to unravel the huge complexity of the depolymerisation product mixture. Traditional gas chromatography (GC) and high- performance liquid chromatography (HPLC) methods applied for this purpose are often in la

Studies of bacterial surface proteins interacting with the immune system

Popular Abstract in Swedish En av de viktigaste substanserna i vår kropp är proteiner, också kallade äggviteämnen. Proteiner har en mängd olika uppgifter i kroppen, de finns i våra celler där de har olika uppgifter såsom att fungera som enzymer, transportörer, signalsubstanser, eller som skyddsfaktorer. Proteiner ingår också som viktiga beståndsdelar i vävnaderna mellan cellerna och finns dessutomPathogenic bacteria express a wide array of surface proteins that interact with the environment. Many of these proteins are believed to be important for the virulence. This thesis deals with the binding of immunoglobulins (Ig) and complement regulating proteins to certain bacterial surface proteins. Protein L from Peptostreptococcus magnus binds to Igk-light chains while protein A from Staphylococ

Circulating Human Basophils and Dendritic Cell Subsets. Aspects of antigen recognition and presentation in type I allergic immune responses

Popular Abstract in Swedish En tredjedel av befolkningen i världens industrialiserade länder lider av allergi, t.ex. allergisk rinit (hösnuva). Trots detta vet man relativt lite om de cellulära och molekylära mekanismer som ligger till grund för det immunologiska svaret vid allergi. Genom att studera dessa mekanismer kan man hitta sätt att angripa dem, vilket förhoppningsvis kan leda till bättre lAllergic diseases currently affect a third of the population in the industrialized parts of the world. Despite this, the cellular and molecular mechanisms involved in the induction and activation of allergic diseases are not fully clarified. Dendritic cells (DCs) link the innate and adaptive immunity and play vital roles in protective immunity against pathogens, as well as in inducing tolerance t

Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo.

Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediated depletion of regulatory T cells (Tregs) in the tumor microenvironment plays a key role in efficaci

Multitask Convolutional Neural Network Emulators for Global Crop Models - Supervised Deep Learning in Large Hypercubes of Non-IID Data

The aim of this thesis is to establish whether a neural network (NN) can be used for emulation of simulated global crop production - retrieved from the computationally demanding dynamic global vegetation model (DGVM) Lund-Potsdam-Jena General Ecosystem Simulator (LPJ-GUESS). It has been devoted to elaboration with various types of neural network architectures: Branched NNs capable of processing in

IL1RAP Blockade with a Monoclonal Antibody Reduces Cardiac Inflammation and Preserves Heart Function in Viral and Autoimmune Myocarditis

BACKGROUND: Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone. METHODS: We induced coxsackie

Annika Fredén

Docent Kontaktinformation E-post: annika [dot] freden [at] svet [dot] lu [dot] se Telefon: +46 46 222 45 54Organisation Statsvetenskapliga institutionen Rumsnummer: 326 Hämtställe: 31 WebbplatsAnnika Fredéns profil i Lunds universitets forskningsportalAndra roller Biträdande universitetslektor Statsvetenskapliga institutionen Profilområdesmedlem LU profilområde: Naturlig och artificiell kognitionS

https://www.svet.lu.se/annika-freden - 2026-05-13

By Who, for Whom? : Landscape, Process and Economy in the Bloomery Iron Production AD 400-1000

Landscape, process and economy in the bloomery iron production during AD 400–1000 are all integrated in this paper initiated by an archaeological exca-vation of a bloomery site in Motala in Östergötland, southeast Sweden. This site is one among other contemporaneous sites with similar features, such as long-term iron production and a location in the landscape within easy reach of communication rou

An Empirical Investigation of the Right to Explanation Under GDPR in Insurance

The GDPR aims at strengthening the rights of data subjects and to build trust in the digital single market. This is manifested by the introduction of a new principle of transparency. It is, however, not obvious what this means in practice: What kind of answers can be expected to GDPR requests citing the right to “meaningful information”? This is the question addressed in this article. Seven insura

On sepsis - epidemiology, prediction and diagnostics

The overall aims of this thesis were to improve prediction, diagnostics and knowledge on epidemiology of sepsis. In paper I, we developed and evaluated an integrated platform for rapid analysis of sepsis-causing organisms directly from blood samples. Testing with blood samples spiked with bacteria and samples from septic patients indicate that the detection limit of the system is in the upper part

Carbon isotope values of hazelnut shells: a new proxy for canopy density

Hazel (Corylus avellana) has been abundant in the vegetation of northern and central Europe since the early Holocene and has provided food and materials for humans ever since. Here we use stable carbon isotope (δ13C) values of hazelnut shells to infer woodland openness based on the premise of the “canopy effect”. It is well established that plants growing in dense, shaded forests have lower carbon

The Territorialisation of the Grocery Shopper: eco-ethical asceticism and environmental nostalgia.

In this chapter we focus on the territorialisation of grocery shoppers and their routes and routines in the city district Western Harbour in Malmö. The Western Harbour is an urban area close to the sea that was built to afford a sustainable and ecologically-friendly way of life. Here we are interested in how the mundane territorialised role of the grocery shopper has evolved among the inhabitants

Temporary dominance and excessive pharmaceutical pricing - CD Pharma (Denmark)

On 31 January 2018, the Danish Competition and Consumer Authority adopted a decision that found the Swedish company CD Pharma, a generic distributor, to be in breach of Article 102(a) TFEU due to having abused its dominant position and imposed excessive and unfair prices for the drug Syntocinon. The company had increased the price of the drug by 2000% on the Danish market in the period April 2014-

Efficient evaluation of humoral immune responses by the use of serum pools

Background: Collection and testing of individual serum samples are often used in research to gain knowledge about e.g. the humoral response against bacteria or virus. This is a valid but time-consuming method and might be a waste of valuable serum samples for inefficient research. So far, no study has considered using serum pools as a quick and efficient screening method to confirm or deny hypothe

Real-Time Adaptive Anomaly Detection in Industrial IoT Environments

To ensure reliability and service availability, nextgeneration networks are expected to rely on automated anomaly detection systems powered by advanced machine learning methods with the capability of handling multi-dimensional data. Such multi-dimensional, heterogeneous data occurs mostly in todays Industrial Internet of Things (IIoT), where real-time detection of anomalies is critical to prevent