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Genetic susceptibility accounts for similar to 35% of all colorectal cancer (CRC). Ten common low-risk variants contributing to CRC risk have been identified through genome-wide association studies (GWASs). In our GWAS, 610 664 genotyped single-nucleotide polymorphisms (SNPs) passed the quality control filtering in 371 German familial CRC patients and 1263 controls, and replication studies were co
Patients with adult acquired flatfoot deformity (AAFD) due to posterior tibial tendon dysfunction (PTTD) may require surgery but few reports have evaluated the outcome.
The usefulness of dietary strategies against cardiometabolic risk is increasingly being acknowledged. Legumes and whole grains can modulate risk markers associated with cardiometabolic diseases, but their possible additive/synergistic actions are unknown. The objective of the present study was to assess, in healthy subjects, the effect of a diet including specific whole-grain barley products and l
The implementation of new surgical techniques offers chances but carries risks. Usually, several years pass before a critical appraisal and a balanced opinion of a new treatment method are available and rely on the evidence from the literature and expert's opinion. The frozen elephant trunk (FET) technique has been increasingly used to treat complex pathologies of the aortic arch and the descendin
A complete census of planetary systems around a volume-limited sample of solar-type stars (FGK dwarfs) in the Solar neighborhood (d a parts per thousand currency signaEuro parts per thousand 15 pc) with uniform sensitivity down to Earth-mass planets within their Habitable Zones out to several AUs would be a major milestone in extrasolar planets astrophysics. This fundamental goal can be achieved w
Purpose of the Study: To identify risk factors for early nursing home placement (NHP) in Alzheimer's disease (AD), focusing on the impact of longitudinal change in cognition, activities of daily living (ADL), service utilization, and cholinesterase inhibitor treatment (ChEI). DESIGN AND METHODS: In an open, 3-year, prospective, multicenter study in a routine clinical setting, 880 AD patients were
A summary is presented of ATLAS searches for gluinos and first- and second-generation squarks in final states containing jets and missing transverse momentum, with or without leptons or b-jets, in the root s = 8 TeV data set collected at the Large Hadron Collider in 2012. This paper reports the results of new interpretations and statistical combinations of previously published analyses, as well as
We present comprehensive results on continuous atmospheric cluster and particle measurements in the size range similar to 1-42 nm within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) project. We focused on characterizing the spatial and temporal variation of new particle formation events and relevant particle formation parameters across Europe. Dif
This book project was initiated at The Tribute Workshop in Honour of Gunnar Sparr and the follow-up workshop Inequalities, Interpolation, Non-commutative Analysis, Non-commutative Geometry and Applications, held at the Centre for Mathematical Sciences, Lund University in May and November of 2008. The resulting book is dedicated in celebration of Gunnar Sparr's sixty-fifth anniversary and more th
This paper addresses the problem of urban transport management in Sofia ? the capital city of Bulgaria. It highlights the tensions and contradictions in the current policy and practice and suggests that the adoption of mobility management in policy making would elevate municipal capacity to deal with complex transport-environment conflicts and set the framework for a sustainable development of the
Den 11 september 2001 innebar början på en stor förändring i amerikansk inrikes och utrikespolitik. I kriget mot terrorismen har en omfattande diskriminering skett av icke-amerikanska medborgare både inom landets gränser såväl som utanför. För att rättfärdiga detta för sitt eget folk samt det internationella samfundet har man i politiken och retoriken skapat bilden av "den andre" som ett
Islands? characteristics provide several advantages as laboratory for studying 100% renewable energy sources (RES) systems. Their isolation makes them a ?unique laboratories, to gain knowledge and understanding of people/environment relationships? ; to prove its feasibility and acquire the needed knowledge for such systems to work; to be pioneer project, basis of other islands? projects and even a
Germany’s current energy grid was built to match energy production from major power plants (coal, gas, nuclear). Due to the 2011 decision to exit all nuclear power until 2022 and ambitious national CO 2 reduction targets, the need to modernise and extend the grid has received substantial attention. In the past, implementation of grid extension projects had shown to be slow and raise serious pu
Beskattning av pokervinster har inte minst under 2011 varit ett ämne för många diskussioner i media. Vissa anser att det krävs stora inslag av skicklighet för att vara duktig på poker och att det inte borde anses vara ett lotteri. Denna skicklighetsaspekt var fall för prövning i HD under 2011 i den s.k. Grebbestadsdomen. Vissa ansåg att domen skulle direkt avgöra om pokervinster skulle komma att bTaxation on poker winnings have not the least in 2011 been a topic of discussion in the media. Some believe that it requires significant element of skill to be good at poker and that it should not be considered a lottery. This skill aspect was tried in the Supreme Court in 2011 in the so-called Grebbestad verdict. Some felt that the appeal would directly determine whether poker profits would be ta
The complement system can be activated by three different pathways in the body. It is wanted to be able to detect deficiencies of these activation pathways and Bioporto A/S has acquired the commercial rights to a set of ELISA based assays. There is a need in these commercial assays for optimisation of dilution and wash buffers since the idea with the ELISA kit is to sell it as a “ready-to-use kit”
One of infiltration ponds used in the preliminary step for drinking water production at Vombverket in the southern part of Sweden was set for the experiment in this study. The pond was split into two sides as one side received the source water from Vomb Lake and (untreated side). For another side, the water from the same source was pre-treated by DynaSand filter and PAC before transferred into the
Type 2 diabetes mellitus (T2DM) in children and adolescents is increasing in the world and the United States of America (US). Previous research has shown that the nurse has an important role in the management of T2DM in children and adolescents but few studies has covered how the nurses perceive and experience this role. This paper aimed to describe how nurses in the US experience their role and t
Olympic legacy was previously seen as a potential burden on the host city, however an evolutionary shift has occurred whereby it can now be regarded as an instrument in wider urban policy planning. Sustainable development is a requirement set by some governments, and London 2012 aimed to use the Olympic legacy for sustainable development in the form of urban regeneration. This paper is a case stud
The development and expansion of artificial intelligence have significant potential to benefit humanity; however, the risks posed by AI-related tools have also become a growing concern over the past decade. From the standpoint of human rights violations AI-related bias, discriminatory practices, data protection practices and violations or potential infringements on fundamental rights are some of t
