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Microglial cells are brain-specific macrophages that swiftly react to disruptive events in the brain. Microglial activation leads to specific modifications, including proliferation, morphological changes, migration to the site of insult, and changes in gene expression profiles. A change in inflammatory status has been linked to many neurodegenerative diseases such as Parkinson's disease and Alzhei

Som en följd av att informationskompetens lyfts fram i Bolognaprocessen som ett betydelsefullt element i all högre utbildning har ämnet uppmärksammats i stigande grad inom universitetsvärlden. Bolognaprocessen har även föranlett ändringar i svensk lagstiftning som gör kursplaner till juridiskt bindande dokument. Kursplanernas lärandemål måste examineras för att man ska kunna säkerställa att de har

Germany’s current energy grid was built to match energy production from major power plants (coal, gas, nuclear). Due to the 2011 decision to exit all nuclear power until 2022 and ambitious national CO 2 reduction targets, the need to modernise and extend the grid has received substantial attention. In the past, implementation of grid extension projects had shown to be slow and raise serious pu

2020-01-31_SE – translated into English 2020-06-11_CK 1 Strategic plan for the Strategic Research Area (SRA) "Epidemiology for Health" (EpiHealth) during the period 2020-2025 The current 5-year strategic plan is based on the previous plan for the years 2017-2021, endorsed by the Board of SRA EpiHealth in accordance with the minutes of the board meeting on January 26, 2017. The basis of this strate

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/epihealth_strategisk_plan_2020-2025_eng_final.pdf - 2026-06-30

BACKGROUND AND AIMS: Sleep disturbance is a prominent complaint in cocaine and alcohol dependence. This controlled study evaluated differences of polysomnographic (PSG) sleep in cocaine- and alcohol-dependent subjects, and examined whether substance dependence interacts with age to alter slow wave sleep and rapid eye movement (REM) sleep.DESIGN: Cross-sectional comparison.SETTING: Los Angeles and

This book project was initiated at The Tribute Workshop in Honour of Gunnar Sparr and the follow-up workshop Inequalities, Interpolation, Non-commutative Analysis, Non-commutative Geometry and Applications, held at the Centre for Mathematical Sciences, Lund University in May and November of 2008. The resulting book is dedicated in celebration of Gunnar Sparr's sixty-fifth anniversary and more th

BACKGROUND: To clarify, in a national sample, associations between risk for seven psychiatric and substance use disorders and five key transitions in Sweden's public educational system. METHODS: Swedish-born individuals (1972-1995, N = 1 997 910) were followed through 12-31-2018, at mean age 34.9. We predicted, from these educational transitions, risk for major depression (MD), obsessive-compulsiv

We measured the thyrotropin response (delta TSH) to 200 micrograms of thyroliberin in 131 subjects without thyroid dysfunction or other disease and with basal values for thyroid function that were within the normal reference intervals for our laboratory. By univariate and multivariate statistical methods we found delta TSH to be significantly influenced by the basal concentration of thyrotropin (T

To understand the origin of disease risk in adulthood, factors in all stages of life and on different contextual levels should be considered. Therefore, the aim of this study was to investigate the relevance of a person's area of residence over their life course with regard to four outcomes: all-cause mortality; ischemic heart disease mortality and morbidity; cancer mortality and morbidity; and re

Islet autoantibodies (IAs) precede the clinical onset of type 1 diabetes (T1D); however, the knowledge is limited about whether the prodrome affects complete blood counts (CBCs) in 4- to 12-year-old children with increased genetic risk for T1D. This study tested whether CBCs were altered in 4- to 12-year-old children without (n = 376) or with one or several IAs against insulin, GAD65, or IA-2 (n =

The European Union’s identity as a normative power has long been examined and contested, most famously by Ian Manners' conceptualization in his 2002 work, Normative Power Europe. This study critically reassesses the EU's proposed identity through the lens of its responses to two pivotal crises: the Syrian conflict (2012-2015) and the 2016 EU-Türkiye Refugee Deal. The research interrogates

Current automated haematology systems lack the functionality of avian blood analysis using 10x magnification, which is an important feature as it allows for faster and more cost-effective blood analysis. The problem originates from the difference in red blood cell morphology in avian blood compared to mammalian blood, as the former are nucleated. The project was divided in two objectives, finding

In this written study, I have researched video game music from the 90’s and early 2000’s to see what I can learn from the process of composing music for video games, as well as how the hardware and software capabilities of the game consoles shaped the music. First it presents my own background and relation to the subject, next it establishes what functionally separates video game music from conven

The survival of our planet is in crisis, and it is affecting society at large. People recognise companies have significantly contributed to the problem, and stakeholders expect and demand businesses to do better. Nowadays, there are strong arguments in sustainability for engaging with as many employees as possible to find novel and innovative solutions more quickly. This study investigated how a p

Introduction The care needs of cancer patients can vary greatly across the course of their serious illness. Despite national efforts to promote supportive care – early integrated palliative care – in Sweden, systemic barriers such as ambiguous terminology and stigma complicate this development. Region Skåne Serious Illness Database (RSSID) is being developed to collect large-cohort data for condu

Contemporary processes of radicalization into far-right extremism are increasingly shaped by digital, online communication environments that convey ideology through multiple communication modes, as well as aesthetic and culturally embedded forms of expression. Short-form content platforms such as TikTok enable fast production and circulation of highly engaging content that creates communicative ar

This thesis examines the extent to which relational preconditions for innovation are institutionalised within the governance framework of the third pillar of Horizon Europe. Departing from the observation that existing research on EU innovation governance has focused predominantly on funding mechanisms and regulatory instruments, the study addresses a conceptual gap: while innovation theory consis

Background Climate change has become one of the leading drivers of global food insecurity, and its effects are felt most strongly in regions such as Sub-Saharan Africa. As environmental degradation and climate-related stresses increasingly affect agricultural production, large buyers of food com- modities become exposed to growing environmental sourcing risks. The United Nations World Food Program