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Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia

Traumatic brain injury (TBI) is a leading cause of chronic brain impairment and results in a robust, but poorly understood, neuroinflammatory response that contributes to the long-term pathology. We used single-nuclei RNA sequencing (snRNA-seq) to study transcriptomic changes in different cell populations in human brain tissue obtained acutely after severe, life-threatening TBI. This revealed a un

‘Someone must do it’ : multiple views on family’s role in end-of-life care – an international qualitative study

Background: Family is a crucial social institution in end-of-life care. Family caregivers are encouraged to take on more responsibility at different times during the illness, providing personal and medical care. Unpaid work can be overburdening, with women often spending more time in care work than men. Objectives: This study explored multiple views on the family’s role in end-of-life care from a

Alzheimer Disease Blood Biomarkers in Patients with Out-of-Hospital Cardiac Arrest

Importance: Blood phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) are promising peripheral biomarkers of Alzheimer disease (AD) pathology. However, their potential alterations due to alternative mechanisms, such as hypoxia in patients resuscitated from cardiac arrest, are not known. Objective: To evaluate whether the levels and trajectories of blood p-tau, Aβ42, and Aβ40 following cardiac a

Brottmålsprocesser rörande patentintrång – En studie av utsikterna för en effektivare tillämpning av patentlagens straffsanktion

Ett patent är en immateriell rättighet som medför en ensamrätt för patenthavaren att dra affärsmässig nytta av en viss uppfinning under en begränsad tidsperiod. Den som kränker patenthavarens ensamrätt gör sig skyldig till patentintrång. Vid patentintrång tillhandahåller den svenska patentlagen (1967:837) ett antal olika sanktionsmöjligheter. De primära civilrättsliga sanktionsformerna utgörs av pA patent is a kind of intellectual property right that grants the patent holder an exclusive right to profit from a certain invention for a limited time period. Anyone who violates the patent holder's exclusive right is guilty of patent infringement. In cases of patent infringement the Swedish Patent Act (patentlag 1967: 837) provides a number of different sanction options. The primary civil s

Regional Brain Net Water Uptake in Computed Tomography after Cardiac Arrest – A Novel Biomarker for Neuroprognostication

Background: Selective water uptake by neurons and glial cells and subsequent brain tissue oedema are key pathophysiological processes of hypoxic-ischemic encephalopathy (HIE) after cardiac arrest (CA). Although brain computed tomography (CT) is widely used to assess the severity of HIE, changes of brain radiodensity over time have not been investigated. These could be used to quantify regional bra

Large regional variation in endovascular thrombectomy rates for acute ischemic stroke in Sweden

INTRODUCTION: Endovascular thrombectomy (EVT) is a significant improvement in the care of acute ischemic stroke (AIS) patients, but only a small portion of patients receive treatment. Our aim was to analyze EVT implementation in Sweden according to a set of key performance indicators (KPIs) for procedural and implementational effectiveness. METHODS: A nationwide prospective registry-based observ

Serum neurofilament light levels are correlated to long-term neurocognitive outcome measures after cardiac arrest

Objective: To explore associations between four methods assessing long-term neurocognitive outcome after out-of-hospital cardiac arrest and early hypoxic-ischemic neuronal brain injury assessed by the biomarker serum neurofilament light (NFL), and to compare the agreement for the outcome methods. Methods: An explorative post-hoc study was conducted on survivor data from the international Target Te

Internet Use and Loneliness Among Older Adults : The Moderating Role of Self-perceptions of Ageing

Loneliness in advanced age has become one of the societal concerns considering its detrimental effects on physical and mental health of older people. Information and communication technologies show the potential to prevent or tackle loneliness and social isolation among older people. Given a percentage of the older population feeling lonely, loneliness in older age has been increasingly recognized

Prediction of Ki-67 expression of breast cancer with a multiparametric model using MRI parameters from ultrafast DCE-MRI and DWI

The purpose of this study is to investigate the prediction of Ki-67 expression of breast cancers using MRI parameters from ultrafast (UF) DCE-MRI, DWI, T2WI, and the lesion size. Breast MRI was performed with a 3T scanner using dedicated breast coils. UF DCE-MRI was obtained using Compressed Sensing-VIBE (prototype sequence). As a kinetic parameter of UF DCE-MRI, maximum slope (MS) was defined as

SONIQO-16

This project explores how a beginner friendly music production device can lower the threshold for engaging with sound creation and rhythm making. Many existing tools rely on prior knowledge or technical skill, which discourages new users from experimenting in creative ways. This project instead focuses on quick feedback, clear interaction and a tactile experience that invites curiosity and play. T

Using Dental Register Information and Questionnaire Data to Assess Periodontitis in Large Cohort Studies

Aim: Periodontitis proxy variables enable an expansion of periodontal research. The study aimed to estimate the validity of questionnaire items and registry data in relation to Stage III–IV periodontitis and having 50% bone loss. Methods: Malmö Offspring Dental Study (MODS) participants (995) filled out questionnaires and underwent periodontal and panoramic radiography examinations. The questionna

The World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology : Part 1 – Lymph Node

Background: Fine-needle aspiration biopsy (FNAB) of lymph nodes is a widely used method for evaluating lymphadenopathy. FNAB offers general advantages of rapid turnaround time, low cost and minimal morbidity, and more specific advantages in various clinical situations, such as deeply located lymph nodes or patients with significant comorbidities. The FNAB sample can be utilized for a wide range of

Multimodal Gene Expression Deep Learning for Predicting Sentinel Lymph Node Macro-metastasis in Early Breast Cancer: Development and Validation in the SCAN-B Cohort

Background: This study evaluates deep learning (DL) using gene expression (GEX) and preoperatively available clinical data (PreopClinic) to predict sentinel lymph node macro-metastasis (SLNM), and explores their potential for guiding axillary surgery de-escalation and supporting prognostic assessment.Methods: We retrospectively included 6,836 clinically node-negative (cN0) T1-T2 patients with inva

Co-production of Climate Services : A diversity of approaches and good practice from the ERA4CS projects (2017–2021)

This guide presents a joint effort of projects funded under the European Research Area for Climate Services (ERA4CS) (http://www.jpi-climate.eu/ERA4CS), a co- funded action initiated by JPI Climate with co-funding by the European Union (Grant 690462), 15 national public Research Funding Organisations (RFOs), and 30 Research Performing Organisations (RPOs) from 18 European countries. This guide set

Prolonged Fatigue and Mental Health Challenges in Critical COVID-19 Survivors

Background: The aim of this study was to investigate the development of fatigue and mental illness between 3 and 12 months after critical COVID-19 and explore risk factors for long-lasting symptoms. Study Design and Methods: A prospective, multicenter COVID-19 study in southern Sweden, including adult patients (≥18 years) with rtPCR-confirmed COVID-19 requiring intensive care. Survivors were invi

Radio propagation modeling methods and tools

This chapter provides overview of fundamental definitions, tools and new methods towards improved channel modeling reported in the Co-operation in Science and Technology (COST)-Inclusive Radio Communications (IRACON) Action for future wireless communications and networks. The overview first covers definitions of propagation environments as they determine most relevant propagation mechanisms to con

ATLAS data quality operations and performance for 2015-2018 data-taking

The ATLAS detector at the Large Hadron Collider reads out particle collision data from over 100 million electronic channels at a rate of approximately 100 kHz, with a recording rate for physics events of approximately 1 kHz. Before being certified for physics analysis at computer centres worldwide, the data must be scrutinised to ensure they are clean from any hardware or software related issues t

EythorssonAndSigurdardottir_WPSS_2

EythorssonAndSigurdardottir_WPSS_2 Working Papers in Scandinavian Syntax 96 (2016), 91–125 A Brief History of Icelandic Weather Verbs∗ Syntax, Semantics and Argument Structure Thórhallur Eythórsson and Sigríður Sæunn Sigurðardóttir University of Iceland and Ghent University Weather verbs in Icelandic are not “no-argument” predicates, but occur with a quasi-argument (non-referential pro) and can al

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/4._Eythorsson-Sigurdardottir_01.pdf - 2026-05-18

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The acceptability of a non-root phenomenon in different types of adverbial clauses in Icelandic Xindan Xu & Ásgrímur Angantýsson University of Iceland Abstract This paper discusses the relatively marked and uncommon subject-initial V3 word order in adverbial clauses in Icelandic and presents results from an online acceptability judgment survey conducted for this study. Following Badan and Haegeman

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_grimm/working_papers/2024-dec/Final_WPSS_XindanAsgrimur-1.pdf - 2026-05-18

Nordlund 11 dec07 t Lena.rtf

Nordlund 11 dec07 t Lena.rtf 78 Gudrun Svensson Funktion och betydelse hos duvet i två gymnasistgrupper i Malmö 1. Inledning 1 Syftet med denna artikel är att diskutera och beskriva funktion och betydelse hos diskurspartikeln duvet2. Som underlag för undersökningarna ligger audioinspel- ningar av två kvinnliga ”kompisgrupper” vid två gymnasieskolor i Malmö, när informanterna gick i årskurs två på

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/Nordlund_Svensson.pdf - 2026-05-18