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Sorting of Breast Cancer Cell into Different Subpopulations towards Long-Term Observation

To study how mechanical factors influence the spread of cancer and the surrounding extracellular matrix (ECM), it is crucial that cancer cell populations be sorted without labels in relevant subpopulations with respect to mechanical properties. It is also important to confine subpopulations for long-term observation to track changes, in inherent properties of the subpopulations, and on the influen

No socioeconomic disparities in the availability of personal care assistance : a population-based cohort analysis of children living with respiratory support

Background: Children aged 0–18 years who need long-term respiratory support rely on medical technology and comprehensive medical care. For this care to be provided at home, access to medical and social support and care is essential. In Sweden, the most notable form is personal care assistance (PCA), which is granted based on legislation and individual authority decisions. We aim to explore the imp

Crosstalk Between GABAergic Neurotransmission and Inflammatory Cascades in the Post-ischemic Brain : Relevance for Stroke Recovery

Adaptive plasticity processes are required involving neurons as well as non-neuronal cells to recover lost brain functions after an ischemic stroke. Recent studies show that gamma-Aminobutyric acid (GABA) has profound effects on glial and immune cell functions in addition to its inhibitory actions on neuronal circuits in the post-ischemic brain. Here, we provide an overview of how GABAergic neurot

ACOUSTOFLUIDIC METHOD TO ALIGN POLYSTYRENE BEADS AND CELLS IN HYDROGEL DROPLETS

We present a microfluidic system to control the position of particles (polystyrene beads or astrocyte cells) in hydrogel droplets using bulk acoustic standing waves. Droplets comprising hydrogel precursor solution, photoinitiator and (bio-)particles were generated and acoustic forces focused the beads to the droplet center line. Droplets were cross-linked by exposure to UV-light. With the acoustic

Highly efficient acoustophoretic single cell-supernatant separation inside nanoliter droplets

This contribution reports a novel method for cell-supernatant separation inside nanoliter droplets with separation efficiencies for single cells of 100% at flow speeds of 2 mm/s. Cells are focused in nanoliter droplets using bulk acoustic waves before the droplet is split at a bifurcation into a supernatant- and a cell-containing droplet. The method enables upconcentration of cells, cell washing,

Peripheral serotonin levels as a predictor of antidepressant treatment response : A systematic review

There are currently no reliable biomarkers to predict clinical response to pharmacological treatments of depressive disorders. Peripheral blood 5-hydroxytryptamine (5-HT; serotonin) has been suggested as a biomarker of antidepressant treatment response, but there has not been an attempt to systematically summarize and evaluate the scientific evidence of this hypothesis. In this systematic review w

Decentralized ventilation unit for window frame integration

Swedish National Board of Housing, Building and Planning reported in "Energi i bebyggelsen"that 80 % of the detached houses in Sweden were under-ventilated, and had a flow of 0.23 l/(s·m2) on average instead of, by the code, required 0,35 l/(s·m2). Well known concerns here are lacking indoor environmental quality and a risk of moisture problems in certain rooms and in the envelope. The naturally v

Classrooms of the present and practices of the past : The importance of understanding physics teachers’ embodied practices as a possible locus for social change

Physics classrooms are still clearly marked by practices belonging to a certaineducational past, while teachers are increasingly being asked to teach in lignment with current equality, diversity and inclusion agendas. At the core of this temporal disconnect are teachers’ practices, which are strongly marked by normative regimes in terms of gender, race, ethnicity, class and other social factors. M

Excited State Processes in Solar Energy Materials

Popular Abstract in Swedish Den globala energianvändningen är idag större än någonsin. Faktum är att den, i takt med världens ständiga utveckling, kommer att fortsätta öka många år framöver. Sättet som energi har producerats på historiskt används dessutom i allra högsta grad fortfarande idag och innebär daglig förbränning av stora mängder organiskt material. Detta resulterar i en ökad koncentratioThis dissertation covers studies of excited state processes in two types of solar energy materials: alternating polyfluorene polymers and their blends with fullerenes in the active layer of plastic solar cells, and bis-tridentate RuII-polypyridyl complexes to be used as sensitizer in systems for artificial photosynthesis. The polymer:fullerene blends were studied by transient absorption and time-

Reliability-driven dynamic binding via feedback control

We are concerned with software that can self-adapt to satisfy certain reliability requirements, in spite of adverse changes affecting the environment in which it is embedded. Self-adapting software architectures are heavily based on dynamic binding. The bindings among components are dynamically set as the conditions that require a self-adaptation are discovered during the system's lifetime. By ado

Development and Reliability Testing of the Nordic Housing Enabler - An Instrument for Accessibility Assessment of the Physical Housing

For decades, accessibility to the physical housing environment for people with functional limitations has been of interest politically, professionally and for the users Guidelines and norms on accessible housing design have gradually been developed, however the built environment shows serious deficits when it comes to accessibility This study addresses development of a content valid cross Nordic v

Fuel Taxes and the Poor: The distributional consequences of gasoline taxation and their implicarions for climate policy

Fuel Taxes and the Poor challenges the conventional wisdom that gasoline taxation, an important and much-debated instrument of climate policy, has a disproportionately detrimental effect on poor people. Increased fuel taxes carry the potential to mitigate carbon emissions, reduce congestion, and improve local urban environment. As such, higher gasoline taxes could prove to be a fundamental part of

Theoretical Foundations for Information Literacy : a Plan for Action

Information literacy is both a common and an important learning activity with higher education. That said, it is under-theorized as a process and as a path to a product. In order to meet the need for theory, the four panelists will offer four distinct possibilities for theoretical frameworks. While the four frameworks are able to stand alone, there is also the likelihood that they might be melded

Differences in antipsychotic treatment between depressive patients with and without a suicide attempt

Background: Depressed suicide attempters are, according to some earlier studies, treated more often with antipsychotics than depressive non-suicide attempters. Cluster B personality disorders, especially borderline personality disorder, are associated with a high suicide risk, and antipsychotics are commonly used for the reduction of symptoms. However, no previous study has taken comorbid personal

Facit urvalsprov191107

1 URVALSPROV MKULÄ 191107 1. En 75-årig kvinna med primär biliär cholangit (PBC) sedan många år och endast sporadiska kontakter med vården utom receptförnyelser av Ursofalk söker akut på akuten på grund av hematemes. Hennes partner beskriver en successiv avtackling med trötthet och förvirring de senaste månaderna. I lab ses ett spontant förhöjt PK på 1,9, trombocyter 85, albumin 28 men normala tra

https://www.medicin.lu.se/sites/medicin.lu.se/files/facit_urvalsprov191107.pdf - 2026-05-27

Multi-photon lithography on thin films for efficient fabrication of 2D and 2.5D meta-atoms

Direct laser writing (DLW) has arise interest in a variety of fields due to the capabilities that we get from the realization of 2D and 3D structures with high resolution fabrication techniques. Multi-photon lithography (MPL) relies on non-linear absorption effects, making possible the fabrication of metasurfaces with feature size beyond the diffraction limit. A new approach in this direction is t

Ekonomistyrning i Professionella Serviceorganisationer – en fallstudie på patentbyrån Albihns Malmökontor

I mer än två årtionden har vi i västvärlden haft en postindustriell serviceekonomi och vi lever idag i ett tjänstesamhälle som under de senaste åren utvecklats i allt högre grad. En stor del av de företag som idag återfinns i tjänstesektorn är professionella serviceorganisationer som arbetar med kvalificerad tjänsteproduktion. Det betyder att de tjänster som erbjuds är kunskapsbaserade produkter.

QUANTIFYING UNCERTAINTY IN INSAR-DERIVED DISPLACEMENT MEASUREMENTS FOR BRIDGE MONITORING

Bridge monitoring is essential for ensuring their long-term safety, reducing disruptions, and supporting economic and social activities. Traditional monitoring techniques rely on periodic inspections and contact-based sensing systems, which, while effective, have limitations due especially to high installation and maintenance costs. Satellite-based Synthetic Aperture Radar Interferometry (InSAR) o