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Objective: Real-life management of hypertensive patients with chronic kidney disease (CKD) is unclear. Methods: A survey was conducted in 2023 by the European Society of Hypertension (ESH) to assess management of CKD patients referred to ESH-Hypertension Excellence Centres (ESH-ECs) at first referral visit. The questionnaire contained 64 questions with which ESH-ECs representatives were asked to e

Objective: Antimuscarinic treatment in fasted mice and rats causes clonic convulsion soon after food intake. This study was designed to evaluate the electrophysiological markers of these convulsions and fasting in electrocorticograms in rats. Methods: Male Wistar albino rats were stereotaxically implanted with 10 cortical electrodes, and baseline electroencephalogram recordings were taken for 10 m

We have developed a microfluidic chip for isolation of circulating tumor cells (CTCs) in blood based on microchannel acoustophoresis. Ultrasound radiation forces are used to separate cancer cells from blood cells in a continuous flow format. Separation was dramatically improved after incorporation of a 2-dimensional acoustic pre-alignment of the cells before entering the acoustophoresis separation

Airborne depth sounding lidar has proven to be a valuable sensor for rapid and accurate sounding of shallow areas. The received lidar pulse echo contains information of the sea floor depth, but also other data can be extracted. We currently perform work on bottom classification and water turbidity estimation based on lidar data. In this paper we present the theoretical background and experimental

We show acoustic separation of 7.8 µm from 5 µm fluorescent polystyrene particles at an unprecedented sample flowrate of almost 1000 µL/min.

Pulmonary arterial hypertension (PAH) is a lethal condition where expansion of the vascular extracellular matrix contributes to increased pulmonary vascular resistance. Versican, a chondroitin sulfate proteoglycan, is known to accumulate in vascular lesions of PAH and hyaluronan and tenascin-C, binding partners of versican, are elevated in PAH. The specific distribution and localization of versica

Square Kilometer Array (SKA) is a project aimed to build the largest radio telescope in the world and it has just gotten into the construction phase. In this phase, the ability to develop and integrate software in an integration environment is crucial as it is the ability to visualize system-related information via a User Interface to rapidly verify the correctness of the system behavior and spot

In the present study, we apply deterministic chaos theory to investigate nonlinear dynamics in monthly precipitation at Mokpo, Korea, after wavelet decomposition. The wavelet transform is used not only for removal of noise but also for extraction of low and high frequency components in the data, representing low-dimensional dynamics. In order to determine an appropriate decomposition level for the

During March 2020 a large-span arena, Tarfalahallen, collapsed. The main load-bearing girders with a 54 m span were high and slender glulam trussed beams, supported from below by a cable system via vertical struts. Investigations concluded that the failure was initiated by out-of-plane buckling of the struts and slender beam, in spite of lateral stabilization by steel roof sheeting at the top edge

This work presents an acoustofluidic chip capable of separating cells form their corresponding secretome for subsequent MALDI-MS analysis, which can be used amongst many other applications for directed evolution.

We have studied a selection of factors influencing the damage of DNA in nanochannels during fluorescence imaging. For cutting and nicking of DNA we show that the DNA is shortened during imaging. To avoid photodamage over the course of several hours of a typical experiment, we demonstrate the importance of an oxygen free gas to propel the buffer solution through the device. Finally, by varying the

Digital technology plays an important role in our work places, and much time is spent in the virtual environments that technol-ogy provides. However, today’s digital work environments are often cumbersome and hard to use, and contribute to stress and ill-health with subsequent cost to the individual, to their employ-ers and to society. Our long-term aim is to facilitate the develop-ment of IT syst

We present a new experimental method for the measurement of the compressibility of cells by analysis of free flow acoustophoresis separation data.

We report a new method to select the optimal actuation frequencies in bulk acoustophoresis devices, by means of differential impedance spectrum analysis measured via the actuating piezoelectric transducer (piezo). The impedance spectra is rich of large spurious resonance peaks originating from bulk resonances not related to the channel resonance, Fig. 1a, why direct measurement of the piezo impeda

The “neurotrophic hypothesis of depression” posits that low levels of brain-derived neurotrophic factor (BDNF) are associated with Major Depressive Disorder (MDD). Low levels of BDNF have also been found in individuals with suicide attempts, in MDD or other disorders, suggesting that low BDNF may also be associated with suicidality. We assessed serum BDNF in 68 physically healthy and unmedicated (

Many ships today rely on Global Navigation Satellite Systems (GNSS), for their navigation, where GPS (Global Positioning System) is the most well-known. Unfortunately, the GNSS systems make the ships dependent on external systems, which can be malfunctioning, be jammed or be spoofed. There are today some proposed techniques where, e.g., bottom depth measurements are compared with known maps using

We present a non-contact platelet functional analysis platform based on acoustic trapping of platelet clusters and activation monitoring using impedance spectroscopy. The system was characterized using polystyrene particles and human platelets. The system was also capable of transferring platelets from plasma into a controlled buffer. Trapped platelets were activated using 20 and 40 μM TRAP and th

Decision-makers and managers spend substantial amounts of funding everyday on various interventions aimed at management of the large carnivores, for example different measures to mitigate depredation on livestock, e.g., removal of carnivores and fencing of livestock (see Linnell et al. 1996 for an extensive review). Management of species that occur in low numbers is challenging as relatively small

One factor which can be expected to influence performance in applications where the user is expected to point a device in some direction to obtain information is the angle interval in which the user gets feedback. The present study was performed in order to get a better understanding of the influence of this angle interval on navigation performance, gestures and strategies in a more realistic outd