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The problem of state estimation of a linear, dynamical state-space system where the output is subject to quantization is challenging and important in different areas of research, such as control systems, communications, and power systems. There are a number of methods and algorithms to deal with this state estimation problem. However, there is no consensus in the control and estimation community o
Programmable metasurfaces constitute an emerging paradigm, envisaged to become a key enabling technology for Reconfigurable Intelligent Surfaces (RIS) due to their powerful control over electromagnetic waves. The HyperSurface (HSF) paradigm takes one step further by embedding a network of customized integrated circuit (IC) controllers within the device with the aim of adding intelligence, connecti
BACKGROUND: To have an impact on the population's health, preventive interventions have to reach a large proportion of the intended population. Digital solutions show potential for providing wider access to fall preventive exercise. However, there is a lack of knowledge about how to reach the target group. The aim of this study was to describe the recruitment process used in the Safe Step randomis
The thesis explores the ‘missing link’ in the study of priority-setting for research, development, and innovation (RDI), namely the processes of implementing RDI priorities, and the consequences of these processes. It does so by focusing on how choices, actions, and motivations of implementers of RDI priorities established elsewhere in the policy system enact, or carry out, the priorities, resulti
The large MIMIC waveform dataset, sourced from intensive care units, has been used extensively for the development of Photoplethysmography (PPG) based blood pressure (BP) estimation algorithms. Yet, because the data comes from patients in severe conditions-often under the effect of drugs-it is regularly noted that the relationship between BP and PPG signal characteristics may be anomalous, a claim
Population ageing is a fact of all advanced economies. Fewer people are born all the while current members live longer. The support which old people have come to depend on, for example through elderly care and pensions, thus becomes increasingly expensive. This accentuates an assurance problem. Although it has been and still is the case that the young are willing to support the currently old, this
While process improvement is an increasingly important topic for organizations, academic institutions find it hard to teach the topic in a cross functional real world project manner. This paper describes a unique course which is theoretically sound, academically rigorous, multi-disciplinary, and practically relevant while providing the students with a transformational learning opportunity. The cou
Men who sell sex to other men are still an under-researched area of study, despite their long presence in our history. But those who are selling sex in the 21st Century have new and peculiar characteristics. This paper highlights the presence of the so-called middle-class, men with high educational credentials that have decided to engage in sex working. Moreover, indulging in the encounter itself
This thesis addresses the theoretical treatment of photoelectrons in attosecond and free-electron laser sciences. Wehave implemented methods that extract information on the photoionization process, which we use to investigateinterferometric schemes with particular focus on multiphoton ionization and strong-field effects in attosecondmetrology and coherent control of photoelectrons in free-electron
Purpose: Caveolin-1 (CAV1) has been implicated in breast cancer oncogenesis and metastasis and may be a potential prognosticator, especially for non-distant events. CAV1 functions as a master regulator of membrane transport and cell signaling. Several CAV1 SNPs have been linked to multiple cancers, but the prognostic impact of CAV1 SNPs in breast cancer remains unclear. Here, we investigated CAV1
Patients admitted to intensive care after cardiac arrest are at risk of circulatory shock and early mortality due to cardiovascular failure. The aim of this study was to evaluate the ability of the veno-arterial pCO2 difference (∆pCO2; central venous CO2 – arterial CO2) and lactate to predict early mortality in postcardiac arrest patients. This was a pre-planned prospective observational sub-study
The device or the formulation? Which one governs drug dispersibility from the inhaler? To address this question, three budesonide-containing reservoir DPIs: Novopulmon Novolizer®, Giona Easyhaler® and DuoResp Spiromax®, were analyzed using the Next Generation Impactor, NGI. Thereafter, the devices were carefully opened, emptied, and formulations were switched between devices. Finally, three ‘proto
We study the long-time behavior of solutions to quasilinear doubly degenerate parabolic problems of fourth order. The equations model, for instance, the dynamic behavior of a non-Newtonian thin-film flow on a flat impermeable bottom and with zero contact angle. We consider a shear-rate dependent fluid the rheology of which is described by a constitutive power law or Ellis law for the fluid viscosi
The COVID-19 pandemic is a crisis that is "creeping" in its onset and "slow-burning" in its duration. It is characterized by extreme uncertainty, ambiguity, and complexity, presenting an unprecedented need for response across sectors and political-administrative levels. While there has been an explosion of research papers into the national strategies for handling the pandemic, empirical publicatio
In recent years, social work with migrants and ethnic minorities has developed as a field of research and practice. Further, it is recognised in the literature that the increased processes of human mobility in today’s societies have driven a growing focus on inclusive cities, especially in larger urban areas where ethnic diversity and cultural heterogeneity can be found alongside newly arrived mig
This Master’s thesis investigates if a previously integrated Simulink based vehicle model works for testing and verifying software on an ECU (electronic control unit) used to control a four-wheel drive coupling in cars. The testing is done through a specific program called CANoe that allows the tester to both develop and run test cases. This work also investigates the possibility to use static eva
As we’re living in a modern society, most of us have been connected to the water and electricity grid, However, there’re still billions of people who are still lack of reliable water and electricity resource. In some developing countries like India and Philippines, the demand for electricity and water are far more than actual production, which causes frequent electricity and water shortage problem
Since their emergence in the 1950’s, ice cores have ventured from being scientific objects of concern to a limited number of glaciologists to becoming one of the most iconic representations of anthropogenic climate change. This thesis aims to historicize the way in which ice cores became enrolled into climate discourse, particularly emphasizing the production and representation of temporalities of
Value at Risk (VaR) is a popular measurement for valuing the risk exposure. Correct estimates of VaR are essential in order to properly be able to monitor the risk. This thesis examines a copula approach for estimating VaR for portfolios of commodities. The predictions are made from a semi- parametric model with Monte Carlo methods. The underlying model is constructed by choosing the best fit from
Inflammation and subsequent endothelial dysfunction are main players in the vascular component of hypertension, and recent findings points to a key role of Sphingosine- 1-Phosphate and its signaling pathways in its pathophysiology. In neurodegenerative disorders such as Alzheimer’s disease, hypertension is the main modifiable risk factor, but insights regarding S1P receptor modulation in response
