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From the flashy to the humble - Towerless Medieval Churches in DenmarkThe article investigates a special category of medieval churches, the towerless churches. The Danish concept for “kullet”, meaning bald headed are discussed, an inventory of the towerless churches is established for medieval Denmark, the architecture is analyzed in relation to different ideals and studied from social and economi
The discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a software package that uses mutational burden and functional impact evidence to identify driver mutation
Context: Effective industry-academia collaboration may increase software engineering research relevance by increased realism, yet very challenging for reasons like confidentiality concerns, different objectives and priorities. Objective: We analyse industry-academia collaboration scenarios based on our own experiences as Ph.D. student and supervisor, and provide insights and recommendations to fac
In this work, we consider the case of a strongly coupled dark/hidden sector, which extends the Standard Model (SM) by adding an additional non-Abelian gauge group. These extensions generally contain matter fields, much like the SM quarks, and gauge fields similar to the SM gluons. We focus on the exploration of such sectors where the dark particles are produced at the LHC through a portal and unde
We demonstrate how water-soluble gold nanoparticles prepared by the citrate reduction method can be functionalized with 11-azidoundecane-1-thiol in a single-step procedure, which combines phase transfer and ligand exchange. The advantages of our method include high reproducibility, low cost of gold nanoparticle production, and rapid and clean ligand exchange, with minimal intermediate steps and no
Introduction: Social robots are accompanied by high expectations of what they can bring to society and in the healthcare sector. So far, promising assumptions have been presented about how and where social robots are most relevant. We know that the industry has used robots for a long time, but what about social uptake outside industry, specifically, in the healthcare sector? This study discusses w
Schlieren imaging has been established as a reliable optical measurement technique for flame visualizations and retrieval of laminar burning velocity information. However, it is off limited capability and adaptability due to the optical configuration of a conventional Schlieren setup. In this regard, background oriented Schlieren (BOS) provides a unique opportunity to quantitatively characterize d
In recent years, a vast number of novel antiphage defense mechanisms were uncovered. To facilitate the exploration of mechanistic, ecological, and evolutionary aspects related to antiphage defense systems, we released DefenseFinder in 2021 (Tesson et al., 2022). De-fenseFinder is a bioinformatic program designed for the systematic identification of known antiphage defense mechanisms. The initial r
In Sweden, cavity walls constructed with autoclaved aerated concrete (AAC) inner leaves and clay brick outer leaves were a common design choice during the 1950s to 1970s. These walls often result in relatively extensive heat losses, leading to reduced indoor thermal comfort. Further, moisture-related issues like frost damage and interior dampness are reported for this wall type. This indicates the
Diverse organophosphate hydrolases have convergently evolved the ability to hydrolyse man-made organophosphates. Thus, these enzymes are attractive model systems for studying the factors shaping enzyme functional evolution. Methyl parathion hydrolase (MPH) is an enzyme from the metallo-β-lactamase superfamily, which hydrolyses a wide range of organophosphate, aryl ester and lactone substrates. In
Selectivity control of aniline oxidation and low reactant conversion in traditional synthesis methods are great challenges, and it is desirable to develop a green, low-cost and highly efficient catalytic route toward value-added products. Herein, an Rb-promoted Fe/CeO2 nanocatalyst was prepared to understand the effects of Rb-promoter on the catalytic performance for the selective oxidation of ani
Objectives: Limited understanding exists regarding non-detected cancers in digital breast tomosynthesis (DBT) screening. This study aims to classify non-detected cancers into true or false negatives, compare them with true positives, and analyze reasons for non-detection. Materials and methods: Conducted between 2010 and 2015, the prospective single-center Malmö Breast Tomosynthesis Screening Tria
BACKGROUND: The incidence of colorectal cancer (CRC) in individuals of fertile age is increasing. Oxaliplatin is a cornerstone treatment in the adjuvant setting for stage III and high-risk stage II CRC. Limited data exist on possible side effects of oxaliplatin on fertility and gonadal function. More data is needed to guide possible fertility preservation procedures and aid evidence-based fertilit
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and functional characterization of mouse and human dendritic cells (DC) from lymphoid organs, and various nonlymphoid tissues. Within this article, detailed protocols are prese
Is being informed about a nudge detrimental to its effect? This paper reports results from an experimental online study testing the effects of transparency on the effectiveness of a default nudge while accounting for psychological reactance and response time. Overall and in line with earlier studies, we find no negative effect of transparency on average behaviour. Adding to the previous discussion
The ever-growing reliance on electronic devices and the burgeoning field of green energy necessitate efficient and different gain AC-DC converters for a myriad of applications, from electric drives to solar cells and grid-connected inverters. This paper introduces a hybrid closed-loop bridged and bridgeless Single-Ended Primary-Inductor Converter (SEPIC) topologies featuring switched-capacitor net
This study develops a strategic framework to guide the adoption of Industry 4.0 technologies across various business sectors. Using a mixed-methods approach, the research combines an extensive literature review with empirical investigations, including case studies and surveys with industry practitioners. The framework integrates advanced digital technologies, such as artificial intelligence and im
