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The present disclosure relates to compositions for reprogramming cells into conventional dendritic cells (cDC), particularly into cDC type 2 (hereinafter referred to as “cDC2” or “CD11b-positive dendritic cells”), methods and uses thereof. The present disclosure relates to the development of methods for making conventional dendritic cells with antigen presenting capacity from differentiated, multi
A novel pretreatment approach was developed in the present study to simultaneously reduce the content of inorganic troubling elements (TEs) and improve biomass energy density, i.e., combined leaching and steam explosion (SE) pretreatment with mechanical pressing. Three different high-ash-containing biomass feedstocks were studied – wheat straw (WS), spruce bark (SB), and empty fruit bunches of oil
Transport in open quantum systems can be explored through various theoretical frameworks, including the quantum master equation, scattering matrix, and Heisenberg equation of motion. The choice of framework depends on factors such as the presence of interactions, the coupling strength between the system and environment, and whether the focus is on steady-state or transient regimes. Existing litera
Abstract An N-Heptane mechanism and a Methane/Propane mechanism have been reduced by an Automatic Reduction Tool (ART) and simulated with two different solver combinations, which solve the set of ordinary differential equations governing the time evolution of the species simultaneously with solving algebraic equations for species that can be considered to be in quasi steady state. The most succes
Neurons derived from neural stem cells could potentially be used for cell therapy in neurodegenerative disorders, such as Parkinson's disease. To achieve controlled differentiation of neural stem cells, we expressed transcription factors involved in the development of midbrain dopaminergic neurons in rat and human neural progenitors. Using retroviral-mediated transgene delivery, we overexpressed L
The concept of ‘sustainable welfare’ conceptualizes welfare and wellbeing within planetary limits. Yet there is a lack of knowledge about possible social and political carriers of corresponding social-ecological transformations. For the promotion of the changes of societal core institutions that climate scientists deem necessary in the nearer future knowledge of which parts of the population are m
Chronic breathlessness is a common and distressing symptom, negatively impacting physical function and quality of life. Many individuals presenting with chronic breathlessness wait years for an explanatory diagnosis, leading to delays in accessing effective treatments and worse individual outcomes including premature mortality. In addition, delays to diagnosis are associated with increased healthc
We compare the electron densities and Hartree potentials in the local density and the Hartree-Fock approximations to the corresponding quantities obtained from more accurate correlated wavefunctions. The comparison is made for a number of two-electron atoms, Li, and for Be. The Hartree-Fock approximation is more accurate than the local density approximation within the 1s shell and for the spin pol
Procedures for sample clean-up and concentration in Capillary Zone Electrophoresis (CZE) have been developed for determination of drugs in biosample s. An on-capillary concentration technique based on enhanced field strengths, the double stacking procedure is introduced. This procedure allows for concentrationg all cations in the sample several hundred times essentially without loss of separation
This qualitative study explored how some working Austrians experienced and coped with changes in their daily occupations after becoming informal carers of persons who had had a stroke. The study provides insights into the working carers' occupational experiences and strategies during a period of pronounced life changes.
Alfa Laval är marknadsledande på teknologin packningsförsedda plattvärmeväxlare (GPHE). För att behålla sin position som marknadsledare inom GPHE-sektorn så utför Alfa Laval regelbundet designstudier. Designstudierna utförs för att undersöka nya lösningar och få inspiration till nya möjliga funktioner. Alfa Laval strävar alltid efter att förbättra sina produkter med avseende på många faktorer, exeAlfa Laval is the market leader within gasketed plate heat exchanger (GPHE) technology. To remain the leader of the GPHE sector, Alfa Laval regularly performs design studies to investigate new solutions and find inspiration for possible functions. Alfa Laval always work to improve their products, regarding many aspects, such as manufacturability, distribution, and maintenance as well as sustainabi
Extrema klimathändelser, såsom betydande översvämningar, utgör en risk för naturkatastrofer. På grund av klimatförändringarnas effekter förväntas södra Sverige få fler betydande regnväder som kan orsaka översvämningar i allt högre grad med mängden utsläpp. I denna studie undersöks dagens och framtidens översvämningsrisk i ett litet område i denna region, inom Kävlinges avrinningsområde. I det framExtreme climate events, such as significant flooding, pose a natural disaster risk. Due to climate change effects, the southern region of Sweden is anticipated to receive more significant rainstorms that could cause flooding increasingly with the quantity of emissions. This study examines the present-day and future climate’s flooding risk in a small area in this region, within the Kävlinge Watersh
Background: Gaming disorder has recently been recognized as a psychiatric condition, yet the clinical characteristics of treatment-seeking individuals remain understudied. This study examined youth and adults seeking treatment at a specialized outpatient clinic in southern Sweden.Methods: A total of 107 individuals aged 12-49 years (M = 22.1, SD = 7.2) underwent comprehensive clinical interviews,
As home care increases and care is moving from nursing homes and hospitals into people’s homes, there are problem areas that need to be addressed and solved in a better way than today. Nurses and other home care workers are exposed to serval risks when the patients’ home environment becomes their workplace. There are also serval risks for the patients when their homes are transferred into “small h
Data acquisition and integration are vital aspects of circular industrial initiatives and help industries develop balanced coordination with other stakeholders and commitment to circular standards. Small and medium-sized enterprises hesitate to implement the necessary automation and information collection process because of high investment issues. The dairy industry does have a growing need for pr
Purpose: This article problematizes the dominant functionalistic and organization‑centric view of employees’ communication engagement on social media and challenges the assumption that such engagement merely reflects managerial success or failure. Adopting an employee‑centred, relational approach, the study advances the understanding of employees’ communication engagement by foregrounding the tensPurpose: This article problematizes the dominant functionalistic and organization‑centric view of employees’ communication engagement on social media and challenges the assumption that such engagement merely reflects managerial success or failure. Adopting an employee‑centred, relational approach, the study advances the understanding of employees’ communication engagement by foregrounding the tens
