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Science, technology and innovation

Science, technology and innovation (STI) are widely perceived as critical factors for sustainable development. The 2030 Agenda defined STI as the central means of sustainable development. The Sustainable Development Goal 17 has three targets that focus on technology transfer, and the United Nations Technology Facilitation Mechanism was launched to promote multi-stakeholder collaboration. While STI

Navigating Health Applications Realms : Consent Challenges and User Empowerment in European Law

This study delves into the landscape of health applications within online markets. These applications, offering health-related functionalities, have become integral to the lives of European citizens. The transformation of healthcare delivery, accelerated by the pace of modern life and accentuated by the COVID-19 pandemic, has elevated health applications from conveniences to essential tools capabl

Inhibitory effect of barusiban and atosiban on oxytocin-induced contractions of myometrium from preterm and term pregnant women

BACKGROUND: A synthetic oxytocin analogue, barusiban, was shown to potently inhibit oxytocin-induced activity of myometrium from term pregnant women. The responsiveness to vasopressin was not influenced by the compound. OBJECTIVE: To test the effect of barusiban and a reference compound, atosiban, on oxytocin-induced activity of myometrium from women at preterm pregnancy in comparison to myometriu

Revisiting Public Support for the Euro, 1999-2017 : Accounting for the Crisis and the Recovery

This paper explores the evolution and determinants of public support for the euro since its creation in 1999 until the end of 2017, thereby covering the pre-crisis experience of the euro, the crisis years and the recent recovery. Using uniquely large macro and micro databases and applying up-to-date econometric techniques, we revisit the growing literature on public support for the euro. First, we

The value of the Skåne Health-care Register : Prospectively collected individual-level data for population-based studies

Aims: This study aimed to examine the population-based Skåne Health-care Register (SHR) regarding feasibility for scientific research and also strengths and weaknesses. Methods: To analyse the feasibility of the SHR, we performed a bibliographic search for peer-reviewed articles based on SHR data from 2000 to 2018. To analyse strengths and weaknesses, we used original SHR data about coverage and v

MetaDL : Declarative program analysis for the masses

While Datalog provides a high-level language for expressing static program analyses, it depends on external tooling to extract the input facts from the analyzed programs. To remove this dependency, we present MetaDL. The MetaDL system consists of a Datalog language extension for source-level program analysis and tools for generating the language extension from a description of the analyzed languag

DNA movement in sub-20 nm nanoslits

The movement of XbaI digested O-DNA in 20 nanometer and O-DNA in 12 nanometer high slits was investigated. We found that DNA moved intermittently and following preferential pathways, indicating an important influence of surface roughness. From these intermittent movements two different mobilities were calculated, the total averaged mobilities and averaged mobilities between the intermittent sticki

Mobile Lab on Sharing in Malmö

Cities are seen as one of the leading forces in making our societies sustainable and resource efficient. The latest trends of sharing homes, cars, bikes, tools and other goods are fast entering our urban lives. The sharing economy is a consumption-production mode in a city, in which value is generated through transactions between peers or organisations that offer access to their idling or underuti

Family members' experiences of care of the dying in residential care homes where the Liverpool Care Pathway was used

Background: Residential care homes (RCHs) are increasingly becoming a common place of death for older people. Aim: The aim of this study was to describe family members' experiences of care of the dying in RCHs where the Liverpool care pathway for the dying patient was used. Methods: This study had a descriptive qualitative study design. Fifteen (n=15) individual interviews were analysed using qual

Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer.

Background: Bladder cancer is categorized as non-muscle invasive (NMIBC) or muscle invasive (MIBC). NIMBC makes up around 70% of the cases and although it is less aggressive, the recurrence rate is 50-70%, thus requiring extensive monitoring. Additionally, there is a risk of progression into MIBC with a 5-year survival of only 50% even when treated with radical cystectomy. Immune checkpoint inhibi

Evaluating care pathways for pediatric anxiety disorders: Study protocol for a pilot randomized controlled trial of stepped care vs stratified care.

Introduction: Anxiety disorders are common and debilitating in children and adolescents. Cognitive behavioral therapy (CBT), delivered both in-person and by the internet (ICBT), is efficacious, but access for young individuals is limited and it remains unclear how to structure the care pathway to maximize benefit.Methods: To inform a fully powered randomized controlled trial (RCT), a pilot RCT wil

Entropy-based spatial heterogeneity analysis in pathological images for diagnostic applications

Clinical pathological diagnosis and prognosis for cancer is often confounded by spatial tissue heterogeneity. This study investigates the utility of entropy as a robust quantitative metric of spatial disorder within Fourier Transform Infrared (FTIR) chemical images of breast cancer tissue. The use of entropy is grounded in its capacity to encapsulate the complexities of pixel-wise spectral intensi

A lipid-based passivation scheme for nanofluidics

Stretching DNA in nanochannels allows for direct, visual studies of genomic DNA at the single molecule level. In order to facilitate the study of the interaction of linear DNA with proteins in nanochannels, we have implemented a highly effective passivation scheme based on lipid bilayers. We show long-term passivation of nanochannel surfaces to several relevant reagents and demonstrate that the pe