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The CSDDD, the EU’s mandatory due diligence directive, is a landmark addition to the EU’s corporate sustainability framework that transforms previously voluntary norms into binding law. Its mandatory due diligence obligations require companies to identify, assess, and address adverse human rights and environmental impacts in their chain of activities, both within and outside the EU. The aim is to
The purpose of this study is to gain a deeper understanding of how HR professionals experience digital HR platforms and how digitalization has influenced and transformed HR work, with particular focus on its social dimensions. The study is based on a qualitative research design and draws on semi-structured interviews with HR professionals in the private sector. The findings show that digitalizatio
The main goal of this thesis is to determine to what degree can there be observed indications for an overvaluation of Internet companies, which in turn may lead to the next asset price bubble in the Internet industry. By conducting an ex-ante analysis, the current study sets out to add additional knowledge in regards to whether and how well the emergence of a bubble can be determined in advance. T
Background: SCOR is a worldwide accepted and renowned process reference model that is developed and endorsed by the non-profit organization Supply Chain Council. It’s a cross-industry diagnostic tool for supply chain management. Consafe Logistics wanted to know if a performance measurement system for warehouse activities could be developed based on the SCOR model, and how it could be applied in th
The MENA (Middle East and North Africa) region enjoys a high availability of clean renewable energy sources, especially solar. In recent years, several countries within the region have introduced policy instruments to encourage the deployment of distributed solar photovoltaic (PV). This thesis reviews and evaluates policy instruments adopted in Egypt, Palestine and Tunisia. The experiences from th
Purpose: To investigate access to basic human rights such as health, a standard of living adequate for health, education, work, marrying and establishing a family, and voting for prosthetic and orthotic users with lower limb disabilities in Malawi. Materials and methods: A cross-sectional design and a questionnaire were used to collect data from 83 participants. Results: Most participants reported
Background Rectal bleeding is considered an alarm symptom for colorectal cancer (CRC) but it is common and mostly caused by benign conditions. Qualitative faecal immunochemical tests (FITs) for occult blood have been used as diagnostic aids for many years in Sweden when CRC is suspected. The study aimed to evaluate the usefulness of FITs requested by primary care physicians for patients with and w
INTRODUCTION: Diabetes mellitus (DM) and colorectal cancer (CRC) share some risk factors, including lifestyle and metabolic disturbances. We aimed to provide in-depth information on the association of CRC risk, especially early-onset CRC, with DM, family history of CRC, and age at DM diagnosis. METHODS: A nationwide cohort study was conducted using Swedish family cancer data sets, inpatient, and o
We investigated type 2 diabetes (T2D) genetic susceptibility via multi-ancestry meta-analysis of 228,499 cases and 1,178,783 controls in the Million Veteran Program (MVP), DIAMANTE, Biobank Japan and other studies. We report 568 associations, including 286 autosomal, 7 X-chromosomal and 25 identified in ancestry-specific analyses that were previously unreported. Transcriptome-wide association anal
Long term multiple systemic antibiotics form the cornerstone in the treatment of bone and joint tuberculosis, often combined with local surgical eradication. Implanted carriers for local drug delivery have recently been introduced to overcome some of the limitations associated with conventional treatment strategies. In this study, we used a calcium sulphate hemihydrate (CSH)/nanohydroxyapatite (nH
Introduction: It remains unclear whether offering psychiatric patients their preferred treatment influences outcomes at the symptom level. Objective: To assess whether offering patients with Panic Disorder with/without Agoraphobia (PD/A) a choice between two psychotherapies yields superior outcomes to random assignment. Methods: In a doubly randomised, controlled preference trial (DRCPT), 221 adul
We propose a multistep approach for representing and classifying tree-like structures in medical images. Tree-like structures are frequently encountered in biomedical contexts; examples are the bronchial system, the vascular topology, and the breast ductal network. We use tree encoding techniques, such as the depth-first string encoding and the Prüfer encoding, to obtain a symbolic string represen
Measurements of atmospheric composition have been made over a remote rainforest landscape. A box model has previously been demonstrated to model the observed daytime chemistry well. However the box model is unable to explain the nocturnal measurements of relatively high [NO] and [O3], but relatively low observed [NO2]. It is shown that a one-dimensional (1-D) column model with simple O3-NOx chemis
Summary: Chronic critical lower limb ischemia (CLI) has been defined as ischemia that endangers the leg. An attempt was made to give a precise definition of CLI, based on clinical and hemodynamic data (Second European Consensus). CLI may be easily defined from a clinical point of view as rest pain of the distal foot or gangrene or ulceration. It is probably useful to add leg ulcers of other origin
Stapylococcus aureus is a common infectious agent in e.g. sepsis, associated with both high mortality rates and severe long-term effects. The cytolytic protein α-hemolysin has repeatedly been shown to enhance the virulence of S. aureus. Combined with an unhindered spread of multi drug-resistant strains, this has triggered research into novel anti virulence (i.e. anti α-hemolysin) drugs. Their func
OBJECTIVE: To describe the organization, content and dosage of interdisciplinary pain rehabilitation, and the differences in degree of severity of problems of patients admitted to clinical units reporting to a Swedish national quality pain registry, grouped according to unit size and possible affiliation with a university hospital. METHODS: Reports from 31 out of 39 clinical units in Sweden, on in
In this paper, a new technique for reconstructing and identifying hadronically decaying τ+τ− pairs with a large Lorentz boost, referred to as the di-τ tagger, is developed and used for the first time in the ATLAS experiment at the Large Hadron Collider. A benchmark di-τ tagging selection is employed in the search for resonant Higgs boson pair production, where one Higgs boson decays into a boosted
Changes in the geometry of ocean meridional overturning circulation (MOC) are crucial in controlling past changes of climate and the carbon inventory of the atmosphere. However, the accurate timing and global correlation of short-term glacial-to-deglacial changes of MOC in different ocean basins still present a major challenge. The fine structure of jumps and plateaus in atmospheric and planktic r
In this study, thermal and hydraulic performance of supercritical liquefied natural gas (LNG) is numerically studied in a printed circuit heat exchanger (PCHE) with airfoil fins under a rolling condition. Effects of operating pressures and rolling parameters are investigated. Results indicate that the PCHE has better thermal performance but worse hydraulic performance at a lower pressure condition
Non-invasive imaging biomarkers (IBs) are warranted to enable improved diagnostics and follow-up monitoring of interstitial lung disease (ILD) including drug-induced ILD (DIILD). Of special interest are IB, which can characterize and differentiate acute inflammation from fibrosis. The aim of the present study was to evaluate a PET-tracer specific for Collagen-I, combined with multi-echo MRI, in a
