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ABSTRACT: Study Design. Prospective randomized controlled study.Objective. To compare the outcome of indirect decompression by means of the X-Stop implant to conventional decompression in patients with neurogenic intermittent claudication due to lumbar spinal stenosis.Summary of Background Data. Decompression is the golden standard for lumbar spinal stenosis nowadays but afflicted with complicatio
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Objectives: The aims of this study were to evaluate the community-based prevalence of atrial fibrillation (AF) in a western society using a geographically well-defined population in the northern part of Sweden as a reference and to estimate the proportion of patients eligible for oral anticoagulation (OAC) prophylactic therapy according to the stroke risk indices CHADS(2) and CHA(2) DS(2) -VASc. B
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Objective: An association between small for gestational age (SGA) and risk for celiac disease (CD) in childhood has previously been reported. However, this association may reflect residual confounding by genetic or environmental factors. For example, presence of subclinical CD in the mother might be a common cause of both SGA and CD in the offspring. We investigate whether SGA is causally associat
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Wilms' tumor (WT), the most common kidney tumor among children, is characterized by a triphasic morphology consisting of blastemal, epithelial, and stromal components. Adult WT is a rare malignancy displaying similar histological features. We here present the first published high-resolution genomic analysis of a mixed-type adult WT. This revealed a more pronounced genetic complexity than usually o
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Aims: This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or CRS without nasal polyps (CRS-NP), in a prospective multi-centre study. Methodology: Two hundred and seven patients with RARS, CRS+NP or CRS-
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Increased intima-media thickness (IMT) has been shown to predict cardiovascular risk, and measurement of intima-media thickness has been extensively used in medical research since the mid-1990s. IMT is conventionally measured by manual tracing, however this method is very time-consuming and suffers from large inter-observer variability. Numerous methods, both semi-automatic and fully-automatic, ha
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The importance of reducing environmental impacts has gained speed in the contemporary global context. Stabilization/Solidification (S/S) has become a practical method for handling polluted dredged sediments to make them usable as a construction material. This study aims to evaluate the environmental and economic impacts of a 48,586 m2 port, with stabilized dredged sediment, by focusing on the prod
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Escherichia coli BL21 (DE3) with a plasmid vector pET-22b (+) carrying xylanase coding gene isolated from an extremely thermophilic bacterium, Thermotoga sp. was used in this work for enhanced production of recombinant xylanase. The study was focused on optimization of lactose based induction for enhanced production of xylanase. Data collected from OFAT and DoE based trails indicated that initiati
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Background: Evidence was found for the effectiveness of virtual reality-based cognitive behavioral therapy (VR-CBT) for treating paranoia in psychosis, but health-economic evaluations are lacking. Objective: This study aimed to determine the short-term cost-effectiveness of VR-CBT. Methods: The health-economic evaluation was embedded in a randomized controlled trial evaluating VR-CBT in 116 patien
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Background: Refugees and asylum-seekers have an elevated risk of mental health issues, such as depression and posttraumatic stress. Qualitative outcome studies can contribute by offering insight into patients’ experiences of what they find beneficial and how they undergo the process of recovery. This study aligns with the small body of qualitative research focusing on refugees’ perspectives of psy
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The human gastrointestinal tract (GIT) is home to a large community of microorganisms that contribute to human health. Delivering live bacteria to the gut for therapeutic purposes can thus be highly beneficial. However, delivering live biotherapeutic products or probiotic bacteria to the GIT presents challenges because the cells must remain viable during production, storage, and administration. En
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Background: Osteonecrosis (ON) is a potentially disabling skeletal complication of cancer treatment. Although symptomatic osteonecrosis (sON) is well-known in acute lymphoblastic leukemia (ALL), with an incidence around 6%, studies on sON in pediatric Hodgkin lymphoma (HL) are scarce. The aim of this study was to examine the incidence, risk factors, and outcome of sON in children treated for HL. P
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The global energy landscape is entrenched in fossil fuels, shaping modern life profoundly. Germany, a prominent example, grapples with transitioning from its fossil-fuelled infrastructure despite governmental support for decarbonization. Carbon capture and storage (CCS) and hydrogen appear as crucial tools in this transition. A recent partnership between Germany and Norway seeks to leverage Norway
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In dynamic operational environments, particularly in collaborative robotics, the inevitability of failures necessitates robust and adaptable recovery strategies. Traditional automated recovery strategies, while effective for predefined scenarios, often lack the flexibility required for on-the-fly task management and adaptation to expected failures. Addressing this gap, we propose a novel approach
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Over the past decade, the healthcare industries have been facing the issue of resource scarcity due to socio-political wars, the COVID-19 pandemic, the luxury lifestyles of people, and the prevalence of single-use medical devices. The circular economy (CE) can be vital in accommodating the evolving patient and provider demands. The CE defies the conventional take-make-dispose process and advocates
