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In September 2023, in the Canadian House of Commons, the Speaker of theHouse introduced the Ukrainian president, Volodymyr Zelensky, to a 98 yearold Ukrainian Waffen-SS veteran named Yaroslav Hunka, who was intro-duced as a “Canadian and Ukrainian hero” and given two standing ova-tions from the floor. This incident developed into an international politicalscandal and resulted in the resignation ofIn September 2023, in the Canadian House of Commons, the Speaker of the House introduced the Ukrainian president, Volodymyr Zelensky, to a 98 year old Ukrainian Waffen-SS veteran named Yaroslav Hunka, who was introduced as a “Canadian and Ukrainian hero” and given two standing ovations from the floor. This incident developed into an international political scandal and resulted in the resignation o

The cardiac hormone atrial natriuretic peptide (ANP) is a central regulator of blood volume and a therapeutic target in hypertension and heart failure. Enhanced ANP activity in such conditions through inhibition of the degradative enzyme neprilysin has shown clinical efficacy but is complicated by consequences of simultaneous accumulation of a heterogeneous array of other hormones. Targets for spe

Aims: Ischaemic coronary artery disease (CAD) remains the leading cause of mortality globally due to sudden death and heart failure (HF). Invasive coronary angiography (CAG) is the gold standard for evaluating the presence and severity of CAD. Our objective was to assess temporal trends in CAG utilization, patient characteristics, and prognosis in HF patients undergoing CAG at a national level. Me

Eutrophication and brownification are ongoing environmental problems affecting aquatic ecosystems. Due to anthropogenic changes, increasing amounts of organic and inorganic compounds are entering aquatic systems from surrounding catchment areas, increasing both nutrients, total organic carbon (TOC), and water color with societal, as well as ecological consequences. Several studies have focused on

Due to the threat climate change poses, the aviation industry needs to adapt. In the process to convert the aviation fleet into a more environmentally friendly fleet, using biofuels such as Sustainable Aviation Fuels as a drop-in fuel remains a promising option. To include biofuels, safety aspects need to be investigated, where combustion instabilities are important. Thermo-acoustic instabilities

This study presents high-fidelity Large Eddy Simulations (LES) of supersonic combustion in a Mach 2 cavity flameholder over the full stable fueling region from 40 to 200 slpm. The simulations employ Finite Rate Chemistry LES with the Z70 ethylene-air mechanism, the Localized Dynamic k-equation model, Partially Stirred Reactor turbulence-chemistry interaction model, conjugate heat transfer, and the

Significance Our results demonstrate the existence of early cellular pathways and network alterations in oligodendrocytes in the alpha-synucleinopathies Parkinson's disease and multiple system atrophy. They further reveal the involvement of an immune component triggered by alpha-synuclein protein, as well as a connection between (epi)genetic changes and immune reactivity in multiple system atrophy

Heart failure (HF) is a leading cause of death and disability globally. Heritable factors and the extent and pattern of myocardial fibrosis are important determinants of outcomes in patients with HF. In a genome-wide association study of mortality in HF, we recently identified a genetic polymorphism on chromosome 5q22 associated with HF mortality. Here, we sought to study the mechanisms by which t

The ABBI (Audio Bracelet for Blind Interaction) device is designed for visually impaired and blind children to wear on the wrist and produce sound based on the movement of the arm through space. The primary func- tion is to inform a child (or adult) about his/her own movements to aid spatial cognition rehabilitation. How- ever, the device could also be worn by friends and family and be used to inf

We aimed to characterize the genomic profiles of adenocarcinomas in the gastroesophageal junction in relation to cancers in the esophagus and the stomach. Profiles of gains/losses as well as gene expression profiles were obtained from 27 gastroesophageal adenocarcinomas by means of 32k high-resolution array-based comparative genomic hybridization and 27k oligo gene expression arrays, and putative

Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of well characterized genes. However, the minimal set of factors necessary for instructing red blood cell (RBC) development remains undefined. We employed a screen for transcription factors allowing direct lineage reprograming from fibroblasts to induced

Fungal cells are exposed to rapidly changing environmental conditions, in particular with regard to the osmotic potential. This requires constant remodeling of the cell wall and, therefore, the cell wall integrity (CWI) MAP-kinase pathway plays a major role in shaping the fungal cell wall to protect from adverse external stresses. To provide a comprehensive functional analysis of the Ashbya gossyp

Enumeration of circulating tumor cells (CTCs) predicts overall survival and treatment response in metastatic cancer, but as many commercialized assays isolate CTCs positive for epithelial cell markers alone, CTCs with little or no epithelial cell adhesion molecule (EpCAM) expression stay undetected. Therefore, CTC enrichment and isolation by label-free methods based on biophysical rather than bioc

BACKGROUND. Understanding the genetic architecture of cardiac structure and function may help to prevent and treat heart disease. This investigation sought to identify common genetic variations associated with inter-individual variability in cardiac structure and function. METHODS. A GWAS meta-analysis of echocardiographic traits was performed, including 46,533 individuals from 30 studies (EchoGen

In Sweden, the debate on the bill to introduce a veil ban in both preschool and primary school has been a relevant debate in recent years. The purpose of the thesis is to analyze the arguments that have been presented in the interpellation debate surrounding the veil ban in the swedish preschool and primary school during the 3rd June of 2019, the debate in council of Malmö City during the 19th of

A detailed sedimentological study was made on six section walls in the Tvärkroken gravel pit, Idre, west-central Sweden. Based on sediment characteristics, three sedimentary units, units 1-3, were identified. The lowest unit, unit 1, was formed by deposition from sediment-loaded underflows into a stagnant basin. A gradual decrease in water depth is indicated in the upper part of this unit. Post-de

Varför väljer utbildare inom FM de utbildningsmetoder de väljer? Vilka faktorer påverkar? Skiljer sig FMs utbildningsmetoder från skolans utbildningsmetoder? Denna studie penetrerar frågorna ur före detta värnpliktigas synvinkel. En litteraturstudie redovisar en jämförelse mellan utbildningsmetoder inom olika utbildningar, inte bara inom skolans värld. En kvantitativ och kvalitativ studie redovisa