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Objective: To update evidence for available therapies in the treatment of hip and knee osteoarthritis (OA) and to examine whether research evidence has changed from 31 January 2006 to 31 January 2009. Methods: A systematic literature search was undertaken using MEDLINE, EMBASE, CINAHL, AMED, Science Citation Index and the Cochrane Library. The quality of studies was assessed. Effect sizes (ESs) an

Plasma metabolomics holds potential for precision medicine, but limited information is available to compare the performance of such methods across multiple cohorts. We compared plasma metabolite profiles after an overnight fast in 11,309 participants of five population-based Swedish cohorts (50–80 years, 52% women). Metabolite profiles were uniformly generated at a core laboratory (Metabolon Inc.)

Importance: Clonal hematopoiesis of indeterminate potential (CHIP) may contribute to the risk of atrial fibrillation (AF) through its association with inflammation and cardiac remodeling. Objective: To determine whether CHIP was associated with AF, inflammatory and cardiac biomarkers, and cardiac structural changes. Design, Setting, and Participants: This was a population-based, prospective cohort

Objective: To examine the associations between five major adverse pregnancy outcomes and long term risks of ischemic heart disease in mothers. Design: National cohort study. Setting: Sweden. Participants: All 2 195 266 women with a first singleton delivery in Sweden during 1973-2015. Main outcome measures: The main outcome measure was incidence of ischemic heart disease from delivery to 2018, iden

This thesis is based on the results concerning the epitaxial growth and characterization of silicon (Si) and germanium (Ge) nanostructures. The growth technique was the Ultra High Vacuum Chemical Vapor Deposition (UHV-CVD) that works in relatively low temperatures and low growth pressures. The UHV-CVD chamber was also used for the reduction experiments. The work presented here involves three diff

Objectives Biologic agents have dramatically changed treatment of rheumatoid arthritis (RA). To date only scarce head-To-head data exist especially when the biological therapies are given as monotherapy without concomitant disease modifying drugs (DMARDs). Thus the objective of the current study is to evaluate treatment response of all available biological therapies with special focus on utility (

Context. X-ray extragalactic surveys are ideal laboratories for the study of the evolution and clustering of active galactic nuclei (AGN). Usually, a combination of deep and wide surveys is necessary to create a complete picture of the population. Deep X-ray surveys provide the faint population at high redshift, while wide surveys provide the rare bright sources. Nevertheless, very wide area surve

The baobab is among the commonly consumed wild fruits found in the semi-arid regions of sub-Saharan Africa. It has a wide application in food systems and folk medicine and has an advantage of surviving even in harsh environmental conditions. While the fruit pulp is packed with a lot of essential nutrients and has gained much interest in recent past on the international market as a healthy ‘superfo

Psykosociala faktorers samband med PMS undersöktes genom en webbaserad enkätundersökning som besvarades av 1320 svensktalande kvinnor och transpersoner med aktiv menscykel. Studien visade samband mellan höga nivåer av PMS och att bo tillsammans med barn eller partner samt att ha en mindre stöttande partner och låg relationstillfredställelse. Personer med en låg utbildningsnivå, egna erfarenheter aThe association between PMS and psychosocial factors was studied using the responses of 1320 women and transgender people with an active menstrual cycle to a Swedish web-based survey. Living with children or a romantic partner was associated with higher levels of PMS, in addition to low relational satisfaction and a less supportive partner. Premenstrual Coping, Perfectionism and Silencing the Self

Idiopatisk normaltryckshydrocephalus (iNPH) är en neurologisk sjukdom som påverkar hjärnans vätskecirkulation och kan leda till symtom som gång- och balanssvårigheter, kognitiv nedsättning och urininkontinens. Sjukdomen drabbar omkring 1.5 % av 70-åringar, och prevalensen ökar med åldern. Det är en svårdiagnostiserad sjukdom där hjärnvätska (CSF) ansamlas i hjärnans hålrum, vilket påverkar hjärnanIntroduction: Idiopathic normal pressure hydrocephalus (iNPH) is a treatable but largely underdiagnosed neurological condition affecting the elderly population. It is characterised by gait and cognitive impairment, as well as urinary incontinence. For the most part, it is diagnosed via imaging and clinical assessments. Abnormalities in cerebrospinal (CSF) flow in the cerebral aqueduct have been li

Background: Most in vitro studies of potential osteoarthritis (OA) therapies have used cartilage monocultures, even though synovium is a key player in mediating joint inflammation and, thereby, cartilage degeneration. In the case of interleukin-1 (IL-1) inhibition using its receptor antagonist (IL-1Ra), like chondrocytes, synoviocytes also express IL-1 receptors that influence intra-articular IL-1

Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon co

Introduction: The demographic changes with population ageing and a rapidly growing share of very old peoplewill put an increasing pressure on the health and social care system. In order to both restrict early retirement and force people to extend their working life reforms are changing pension systems in many European countries. Besides that older people have to extend their working life it is imp

IMPORTANCE The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core neuropathological feature of Alzheimer disease (AD), but its diagnostic utility is unclear. OBJECTIVE To examine the discriminative accuracy of [18F]flortaucipir for AD vs non-AD neurodegenerative disorders. DESIGN, SETTING, AND PARTICIPANTS In this cross-

Importance: Patients with amnestic mild cognitive impairment (aMCI) may progress to clinical Alzheimer disease (AD), remain stable, or revert to normal. Earlier progression to AD among patients who were β-amyloid positive vs those who were β-amyloid negative has been previously observed. Current research now accepts that a combination of biomarkers could provide greater refinement in the assessmen

The concept of “Sustainable water use” (SWU) aims to assure three pillars of sustainability related to the water sector: the social, environmental, and economical. Industrial development, especially in developing countries, requires an adequate response, as industrial activities are recognized as one of the major sources of water pollution, what leads to deterioration of environmental safety and w

Acknowledgements A M m Masters’ Thesis for LUMES - Lund University International Master’s Programme In Environmental Science 2003-2004 PET Bottle System in Sweden and Japan: an Integrated Analysis from a Life-Cycle Perspective uthor: ichiko Amano ichiko.amano.025@student.lu.se Supervisor: Barry Ness barry.ness@miclu.lu.se Lund, Sweden, November 2004 mailto:michiko.amano.025@student.lu.se mailto:ba

https://www.lumes.lu.se/sites/lumes.lu.se/files/amano_michiko.pdf - 2026-05-15

Microsoft Word - LUMES_Thesis_2007_Steven_Canty.doc.doc Positive and Negative Impacts of Dive Tourism: The Case Study of Utila, Honduras. Steven W. J. Canty Ällingavägen 7B: 511 227 34 LUND, Sweden email: steven.canty@gmail.com Submitted in fulfilment of the requirements for the International Master’s Programme in Environment Studies and Sustainability Science. Supervised by Mats Svensson Lund Uni

https://www.lumes.lu.se/sites/lumes.lu.se/files/steven_canty.pdf - 2026-05-15

Template - Simplified procedure [Translation from Swedish to English] Inst/Dept/Unit Officer dealing with the matter/Title 21 Address NAME OF DOCUMENT File ref. 1 Date Procurement document, simplified procurement of XXX 1 Administrative provisions Lund University is issuing an invitation to tender for ***XXX***. This procurement document includes all of the information, requirements, terms and con

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/template_simplified_procedure.docx - 2026-05-15