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Single nucleotide polymorphisms in the 20q13 amplicon genes in relation to breast cancer risk and clinical outcome

The 20q13 region is frequently amplified/overexpressed in breast tumours. However, the nature of this amplification/overexpression is unknown. Here, we investigated genetic variation in five 20q13 amplicon genes (MYBL2, AURKA, ZNF217, STK4 and PTPN1) and its impact on breast cancer (BC) susceptibility and clinical outcome. As a novel finding, four polymorphisms in STK4 (rs6017452, rs7271519) and A

Sustained postprandial decrease in plasma levels of LDL cholesterol in patients with type-2 diabetes mellitus

Objective . Low density lipoprotein cholesterol (LDL-C) is an independent and modifiable risk factor for development of cardiovascular disease (CVD). Postprandial lipid metabolism has been linked to CVD, but little is known about the postprandial LDL-C profile in patients with type-2 diabetes (T2DM). We aimed to study the postprandial levels of LDL-C in T2DM patients. Material and methods . After

Mild hypothermia markedly reduces ischemia related coronary t-PA release.

In experimentally induced myocardial ischemia, mild hypothermia (33-35 degrees C) has a robust cardioprotective effect. Tissue plasminogen activator (t-PA) is a profibrinolytic enzyme that is released from the vascular endothelial cells in response to ischemia and other injurious stimuli. t-PA has also been found to have proinflammatory properties that could contribute to reperfusion injury. We po

Non-invasive assessment of magnitude and dispersion of atrial cycle length during chronic atrial fibrillation in man

AIMS: Atrial fibrillation cycle lengths can be assessed from right precordial ECG leads and the unipolar oesophageal ECG using a non-invasive method called Frequency Analysis of Fibrillatory ECG. The purpose of this report is to present the results from application of this method in a large group of patients with long-term atrial fibrillation and to examine the differences between patients with 'c

Klimatanpassad byggnad för varma somrar och kalla vintrar

Outdoor climate has considerable impact on the indoor climate and it is therefore important to adapt the buildings to the climate. This thesis shows how to improve indoor climate in a climate which it is hot, dry in the summer and cold in the winter. My investigative unit is a middle class house in the town Baalbek in Lebanon and the purpose of the study is to come up with proposals on possible so

Comparison of saproxylic beetle diversity in urban parks and rural areas

Dead wood is a key element in forest ecosystems and a wide range of organisms are dependent on this substrate for development and reproduction. Saproxylic beetles are important decomposers of dead wood and serve as food for many organisms. Due to the significant forestry-related decrease of dead wood in rural areas, many species of saproxylic beetles are considered threatened. Thus, other spaces h

Spray-dried powders for inhalation

The pulmonary route has emerged as a promising strategy for delivering protein therapeutics, particularly for patients suffering from respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary infections. This project investigated the effect of operating parameters of a laboratory spray dryer on the characteristics of powders composed of Bovine Serum Albumin

The role of 30x30 MPAs in protecting endangered sharks in the Northwestern Atlantic and their associated habitats

Sharks are an ecologically important group of fishes important to maintaining ecosystem structure and function, yet the additive effects of climate change and anthropogenic activities threaten their survival. Northwestern Atlantic populations of shortfin mako sharks and white sharks are considered threatened species, with populations in decline since the 1950s. Previous conservation efforts have a

Brief admission by self-referral for adolescents who self-harm : discourses on involvement and responsibility among parents and other significant adults

BACKGROUND: Brief Admission by self-referral (BA) was implemented in 2018 in Swedish child and adolescent psychiatric (CAP) inpatient care. This intervention empowers adolescents to self-admit at their own request for brief periods to prevent self-harm and suicidal crisis. As BA enhances healthcare user autonomy, it is a timely intervention to consider with the emerging human rights discourse and

Life Cycle Assessment of 5-Hydroxymethylfurfural: Feedstock comparison and hotspot analysis

5-Hydroxymethylfurfural (HMF) is a versatile bio-based platform chemical that can substitute fossil-derived intermediates in polymers, solvents, and fuels, thereby contributing to a fossil-free chemical industry. While first-generation feedstocks such as high-fructose corn syrup have been widely studied, their use raises concerns about competition with food supply. In contrast, second-generation r

Long-term exposure to air pollution and road traffic noise in relation to dispensed antidepressant medications : A Swedish cohort study

Background: The impact of air pollution and road traffic noise on depression remains inconclusive. This study examined long-term residential exposure to air pollutants and road traffic noise in relation to dispensed antidepressant medications. Methods: A cohort study was conducted using the Swedish Malmö Diet and Cancer Study, with the outcome defined as a first dispensed antidepressant (ATC: N06A

Discharge and sediment transport in the Kapuas river

Deteriorating water quality is a challenge which affects people of the entire world, with a growing population and increased industrialization worldwide. The problem is especially apparent in many developing nations where water resource management must be improved to secure a future sustainable supply. This study was undertaken as a bachelor degree within the MFS-program funded by SIDA. The study

Equal responsibility, unequal ability : allocation of environmental responsibility in pro-environmental behavior research

Neoliberalism, as a loosely defined set of political beliefs, calls for more individual freedom and autonomy, resulting in increased responsibility for each person to address major societal issues. ‘Individualization’ is the process by which responsibility for addressing major environmental issues such as climate change is placed on individuals. In this thesis I investigate whether individualizati

Dykeriarbete ac

Dykeriarbete Dykeriarbete Om du ska dyka och andas andnings-gas under förhöjt tryck, måste du följa Arbetsmiljöverkets föreskrifter om dykeriarbete AFS 2010:16. Kontakta husprefekt om du planerar att dyka i arbetet. • Skriftlig dykplan baserad på en riskbedömning ska göras. • Riskbedömningen ska dokumenteras, dateras och lagras i lämplig form. • Den som genomför riskbedömningen ska ha god kunskap

https://www.geologi.lu.se/sites/geologi.lu.se/files/dykeriarbete_ac.pdf - 2026-05-30

LU-nytt 4

Publicerad 11 mars. Universitetsgemensamma nyheter Visa fler nyheter Aktuellt från universitetsledningen Erik Renström, rektorFrån rektorsbloggen: "När regeringen nyligen lade fram sin proposition om migrationsrättsliga regler för forskare och doktorander kan jag konstatera att den går i en riktning som ytterligare förenklar den för oss så viktiga mobiliteten för internationella forskare och dokto

https://www.medarbetarwebben.lu.se/kategori/lu-nytt-4-2026 - 2026-05-30

Mven14 schema ht15 v2

Tillämpad Miljövetenskap Schema Tillämpad Miljövetenskap HT 2015 Kursen består av föreläsningar, övningar och ett individuellt projektarbete som löper över hela kursperioden. Kursinformation, föreläsningar och annat material kommer att finnas på kurswebben: live@lund. Ni kommer att få användarnamn och lösenord skickat till er via email. Möten med handledare och kursledare är inte inlagda med exakt

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven14_schema_ht15_v2.pdf - 2026-05-30

210422 vaccination program (002) 0

Covid-19 En streamad föreläsning om vaccination, med anledning av den pågående pandemin med covid-19. Vaccinationstemat kommer att belysas ur flera olika perspektiv. Introduktion av kvällens moderator (17.30) Joakim Esbjörnsson-Klemendz, docent, Systemvirologi, Lunds universitet Bakgrund om vaccin. Vad kan det skydda mot? (17.40)  Kristian Riesbeck, professor och överläkare, Lunds universitet och

https://www.virology.lu.se/sites/virology.lu.se/files/2021-04/210422_vaccination_program%20(002)_0.pdf - 2026-05-30