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The transition within business from a linear to a circular economy brings with it a range of practical challenges for companies. The following question is addressed: What are the product design and business model strategies for companies that want to move to a circular economy model? This paper develops a framework of strategies to guide designers and business strategists in the move from a linear
Let R denote a connected region inside a simple polygon, P. By building barriers (typically straight-line segments) in P∖R, we want to separate from R part(s) of P of maximum area. All edges of the boundary of P are assumed to be already constructed or natural barriers. In this paper we introduce two versions of this problem. In the budget fence version the region R is static, and there is an uppe
Modern wind turbines are designed to withstand approximately for a lifetime of 20 years [1]. However, a very long design life of 100 years or more can be expected for high-quality concrete foundations. Thus there is a big difference in lifetime between wind turbines and foundations. There is a significant economic benefit of replacing the out-of-date wind turbine with a new turbine of better power
OBJECTIVE: To evaluate a system for delivery of inhaled nitric oxide.DESIGN: Prospective, laboratory study.SETTING: Engineering laboratory.SUBJECTS: A standard ventilator (Servo Ventilator 300), supplemented with extra gas modules for nitric oxide delivery.INTERVENTIONS: Two ventilator-integrated gas modules, delivering < or = 10 parts per million (ppm) or < or = 100 ppm of nitric oxide, were used
Today's test methods used for verifying the performance and robustness of automotive applications using wireless communication are often based on fieldtrails, which are time consuming, costly, and not repeatable. Therefore, there is an urgent need for new verification methods that can be performed in lab environment, where the realistic radio propagation environment can be emulated. The telecom in
The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitat
The human brain can be seen as an ensemble of interconnected neurons, more or less specialized to solve different cognitive and motor tasks. In computer science, the term deep learning is often applied to signify sets of interconnected nodes, where deep means that they have several computational layers. Development of deep learning is essentially a quest to mimic how the human brain, at least part
OBJECTIVE: To compare neurofilament light (NfL) and tau as blood-based biomarkers for acute sports-related concussion (SRC) and determine whether their concentrations at different time points after the injury are associated with prolonged time to return to play (RTP).METHODS: A total of 288 professional hockey players were followed longitudinally from September 1, 2012, to April 30, 2015. Data col
Free-floating bike sharing systems are an emerging new generation of bike rentals, that eliminates the need for specific stations and allows to leave a bicycle (almost) everywhere in the network. Although free-floating bikes allow much greater spontaneity and flexibility for the user, they need additional operational challenges especially in facing the bike relocation process. Then, we suggest a m
Genome scans for quantitative trait loci (QTL) in farm animals have concentrated on primary production and health traits, and information on QTL for other important traits is rare. We performed a whole genome scan in a granddaughter design to detect QTL affecting body conformation and behavior in dairy cattle. The analysis included 16 paternal half-sib families of the Holstein breed with 872 sons
„White biotechnology“- the third and latest wave of biotechnology - is aiming to replace the well-established C2/C3 chemistry based on oil and gas by biological processes. The backbone of biotechnology is the conversion by fermentation which is widely established in the production of antibiotics, enzymes, bioethanol and organic acids. One of the key concepts related to “white biotechnology” are so
IntroductionIncreasing oil prices and growing environmental concerns in recent years have driven the development of renewable biofuels. Stimulated by this, the European production of bioethanol, which is produced by fermentation of sugar components in biomass, has nearly doubled in the last two years increasing from 913 million litres in 2005 to 1,565 million litres in 2006. The continuation of
Isosorbide is a stiff bicyclic diol derived from glycose-based polysaccharides, and is thus an attractive building block for novel rigid bioplastics. In the present work a highly regioselective biocatalytic approach for the synthesis of isosorbide 5-methacrylate was developed. The Lipozyme RM IM (Rhizomucor miehei lipase) catalyzed process is straightforward, easily scalable and chromatography-fre
Antioxidants are important molecules that are widely used by humans, both as dietary supplements and as additives to different types of products. In this chapter, we review how flavonoids, a class of polyphenolic antioxidants that are often found in glycosylated forms in many natural resources, can be extracted and modifi ed using glycoside hydrolases (GHs). Glycosylation is a fundamental enzymati
This paper presents an ongoing research project investigating the use of bibliometrics for research evaluation and resource allocation purposes, and to investigate the effects of these evaluation models on individual, organizational and political levels. A main focus has been on bibliometrics based evaluation practices. The use of bibliometrics for local resource allocation at Swedish universities
