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We show that tree-like resolution is not automatable in time no(log n) unless ETH is false. This implies that, under ETH, the algorithm given by Beame and Pitassi (FOCS 1996) that automates tree-like resolution in time no(log n) is optimal. We also provide a simpler proof of the result of Alekhnovich and Razborov (FOCS 2001) that unless the fixed parameter hierarchy collapses, tree-like resolution
Background: The aggressive nature of breast cancers detected between planned mammographic screens, so-called interval cancers, remains elusive. Here, we aim to characterise underlying molecular features of interval cancer. Methods: From 672 patients with invasive breast cancer, we analysed gene expression differences between 90 ‘true’ interval cancer cases (i.e. women with low-dense breasts define
I present an empirically based argument for the plausibility of misrepresentation as posited by some higher-order theories of consciousness. The argument relies on the assumption that conscious states are generated by processes in the brain. The underlying idea is that if the brain generates conscious states then misrepresentation may occur. The reason for this is that brain states can be corrupte
This article analyses existing assumptions about state identity within contemporary International Relations theory, arguing that the quest for the identity of the state leads to either circularity or regress. Departing from commonsensical criteria of self-identity such as indivisibility, distinctness and spatiotemporal continuity, this article examines how these criteria are interpreted and applie
PARP14/BAL2 is a large multidomain enzyme involved in signaling pathways with relevance to cancer, inflammation, and infection. Inhibition of its mono-ADP-ribosylating PARP homology domain and its three ADP-ribosyl binding macro domains has been regarded as a potential means of therapeutic intervention. Macrodomains-2 and -3 are known to stably bind to ADP-ribosylated target proteins, but the func
MILJÖVETENSKAP Preliminärt schema 2019-10-02 Kurs: MVEN16 Klimatpolitik, samhällsstyrning och kommunikation, HT19 Kursansvarig: RH: Roger Hildingsson, Statsvetenskapliga inst; roger.hildingsson@svet.lu.se Lärare: CD: Carl Dalhammar, IIIEE; carl.dalhammar@iiiee.lu.se JAO: Johanna Alkan Olsson, CEC/Miljövetenskap; johanna.alkan_olsson@cec.lu.se JK: Jamil Khan, Miljö- och energisystemanalys, LTH; jam
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven16_schema_ht19_prel.pdf - 2026-07-01
Lägg till titel FÖRSÄTTSSIDA STYRDOKUMENT Kvalitetspolicy för Lunds universitet Typ av styrdokument: Policy Definition av typen av styrdokument: En policy uttrycker ledningens övergripande viljeriktning eller värden som ska beaktas inom det område policyn omfattar och sätter ramarna för ett visst handlande och utgör en stark rekommendation om ett visst handlingssätt. Beslutsfattare: Universitetsst
BACKGROUND: micro RNAs (miRNAs) are important regulators of many biological pathways. A plethora of steps are required to form, from a precursor, the mature miRNA that eventually acts on its target RNA to repress its expression or to inhibit translation. Recently, Drosophila nibbler (nbr) has been shown to be an important player in the maturation process of miRNA and piRNA. Nbr is an exoribonuclea
Fat cadherins constitute a subclass of the large cadherin family characterized by the presence of 34 cadherin motifs. To date, three mammalian Fat cadherins have been described; however, only limited information is known about the function of these molecules. In this paper, we describe the second fat cadherin in Drosophila, fat-like (ftl). We show that ftl is the true orthologue of vertebrate fat-
The glycosaminoglycan hyaluronic acid (HA) is an important component of the extracellular matrix (ECM) in the brain. CD44 is a cell adhesion molecule that binds to HA in the ECM and is present on astrocytes, microglia and certain neurons. Cell adhesion molecules have been reported to be involved in anxiety and mood disorders. CD44 levels are decreased in the cerebrospinal fluid (CSF) of depressed
Background: The neural transcription factor SOX11 has been described as a prognostic marker in epithelial ovarian cancers (EOC), however its role in individual histological subtypes and tumour grade requires further clarification. Furthermore, methylation-dependent silencing of SOX11 has been reported for B cell lymphomas and indicates that epigenetic drugs may be used to re-express this tumour su
Burdur Lake, which is located in southwest of Turkey in Lake Region, and has been drying rapidly in the last 30 years. Disappearance of the water from the lake brings dramatic changes to the region on both socio-economic and cultural levels. This paper explores the processes that brought Burdur Lake and its locals to the point where the lake is today. Transformations in cultural habits and everyda
When talking about gender equality work in public sector in Sweden two words come to mind, ‘gender’ and ‘mainstreaming’. Gender mainstreaming is Sweden’s official strategy to reach the national gender equality goals. Despite its popularity the strategy has received criticism for being too fixated on process and thus mainly focusing on methods, tools and policy instruments instead of addressing the
