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Secretion and Dipeptidyl Peptidase-4-Mediated Metabolism of Incretin Hormones after a Mixed Meal or Glucose Ingestion in Obese Compared to Lean, Nondiabetic Men.

Context: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are cleaved by dipeptidyl peptidase-4 (DPP-4); plasma activity of DPP-4 may be increased in obesity. The impact of this increase on incretin hormone secretion and metabolism is not known. Objective: The aim of the study was to assess incretin hormone secretion and degradation in lean and obese nondiabet

Injury markers predict time to dementia in subjects with MCI and amyloid pathology.

OBJECTIVES: Alzheimer disease (AD) can now be diagnosed in subjects with mild cognitive impairment (MCI) using biomarkers. However, little is known about the rate of decline in those subjects. In this cohort study, we aimed to assess the conversion rate to dementia and identify prognostic markers in subjects with MCI and evidence of amyloid pathology. METHODS: We pooled subjects from the VU Un

Weight-change as a prognostic marker in 12 550 patients following acute myocardial infarction or with stable coronary artery disease.

Aims To examine the prognostic importance of weight-change in patients with coronary artery disease (CAD), especially following acute myocardial infarction (AMI). Methods and results In 4360 AMI patients (OPTIMAAL trial) without baseline oedema, we assessed 3-month weight-change, baseline body mass index (BMI), demographics, patient history, medication, physical examination, and biochemical analys

Prevalence of Metabolic Syndrome in Adult Hypopituitary Growth Hormone (GH)-Deficient Patients Before and After GH Replacement.

Context and Objective: Metabolic and body compositional consequences of GH deficiency (GHD) in adults are associated with a phenotype similar to the metabolic syndrome (MetS). Patients: We assessed MetS prevalence in adult GHD patients (n = 2531) enrolled in the Hypopituitary Control and Complications Study. Prevalence was assessed at baseline and after 3 yr of GH replacement in a subset of 346 ad

Continuous amplitude-integrated electroencephalogram predicts outcome in hypothermia-treated cardiac arrest patients.

OBJECTIVE:: To assess the prognostic value of continuous amplitude-integrated electroencephalogram in comatose survivors after cardiac arrest and treated with hypothermia. DESIGN:: Prospective observational study. SETTING:: General intensive care unit at a university hospital. PATIENTS:: Comatose patients after cardiac arrest and treated with hypothermia. INTERVENTIONS:: Patients were sedated and

Clinically Assessed Mediolateral Knee Motion: Impact on Gait.

OBJECTIVE: Mediolateral knee movement can be assessed visually with clinical tests. A knee-medial-to-foot position is associated with an increased risk of knee injuries and pathologies. However, the implications of such findings on daily tasks are not well understood. The aim of this study was to investigate if a knee-medial-to-foot position assessed during a clinical test was associated with alte

CH Styrelse 2024-02-13 Protokoll

LUNDS UNIVERSITET Sida 1 av 6 PROTO KOLL CAMPUS HELSINGBORG Sammantradesdatum 2024-02-13 Diarienummer STYR2024/570 Utveckl i ng sen hete n Protokoll Campus Helsingborgs styrelse Narvarande ledamoter Lena Eskilsson ordforande, prorektor LU Charlotta Johnsson rektor, Campus Helsingborg Agnes Andersson dekan, Samhallsvetenskapliga fakulteten Annika Olsson rektor, Lunds tekniska hogskola deltog via Zo

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2024-03/CH%20Styrelse%202024-02-13%20protokoll.pdf - 2026-05-11

Vildagliptin Reduces Glucagon during Hyperglycemia and Sustains Glucagon Counterregulation during Hypoglycemia in Type 1 Diabetes.

Context: The dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits glucagon secretion at hyperglycemia but appears to enhance glucagon counterregulation during hypoglycemia in type 2 diabetes.Objective:The objective of the investigation was to study whether vildagliptin also improves α-cell function in type 1 diabetes (T1D). Patients and Methods: The study was a single-center, double-blind, ra

Metabolic risk factors for esophageal squamous cell carcinoma and adenocarcinoma: a prospective study of 580 000 subjects within the Me-Can project

Background: Obesity is associated with an increased risk of esophageal adenocarcinoma (EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However, little is known about the risk of EAC and ESCC related to other metabolic risk factors. We aimed to examine the risk of EAC and ESCC in relation to metabolic risk factors, separately and combined in a prospective cohort study. Metho

Arsrapport mh final 2010

Microsoft Word - MH - Årsrapport 2010[2].doc 1 Årsrapport 2010 för Enheten för medicinens historia, Medicinska Fakulteten, Lunds universitet Enheten för medicinens historia har under året 2010 fortsatt sin verksamhet som en fristående enhet inom Institutionen för kliniska vetenskaper (IKVL) i Lund (prefekt Roland Andersson, sektion 5 med chef Freddy Ståhlberg). Enheten leds av undertecknad (på 30%

https://www.medicinhistoria.lu.se/sites/medicinhistoria.lu.se/files/arsrapport_mh_final_2010.pdf - 2026-05-11

The fate of pebbles and planetesimals entering protoplanetary envelopes

De mest framgångsrika planetbildningsmodellerna som forskare jobbar med idag härstammar från en idé som kom fram för nästan 300 års sedan, under 1700-talet. Det var den svenske forskaren Emanuel Swedenborg och den tyske filosofen Immanuel Kant som kom fram med en hypotes som vi idag kallar Solnebulosan. Idén bygger på att solen bildades från ett gigantiskt stoftmoln som kollapsade, på grund av graPlanetary embryos grow by the accretion of solid dust-material, ranging from cm- to m-sized pebbles up to km-sized planetesimals. However, the underlying size-distribution of the accreted material is poorly understood. When the pebbles and planetesimals encounter a protoplanet, they are subjected to the gaseous environment of the protoplanetary envelope. Because of the drag-force from the gas, the

2024 05 07 PhD admin guide 2024

Latest update: 22/04/2024 1 Guide for PhD students at INES WELCOME to the INES PhD Administrative Guide. More than thirty-five PhD students are currently conducting research here on a wide range of topics pertaining to the Earth's system. Both in terms of nationality (students from every continent except Antarctica) and research areas, we are incredibly diverse. We have a good mix of modelers, rem

https://www.nateko.lu.se/sites/nateko.lu.se/files/2024-05/2024_05_07_PhD_admin_guide_2024.pdf - 2026-05-11

MSc-LLA

In Quest of Excited States in 61Ga Lise-Lotte Andersson Master Thesis Department of Physics Division of Nuclear Physics Lund University 2004 LUNFD6/(NFFR-5022)1-47/(2004) Abstract: In an attempt to extend the knowledge of mirror nuclei into the mass A = 60 region, the fusion evaporation reaction 40Ca + 24Mg at 104 MeV was used to identify excited states in the hitherto unknown isotope 61 31 Ga30.

https://www.particle-nuclear.lu.se/sites/particle-nuclear.lu.se/files/2023-12/MSc-LLA.pdf - 2026-05-11

Returns within Fashion E-Tailing

The purpose of this master’s thesis is to provide a contribution to the research body regarding consumer returns, particularly within the online fashion retail industry. A quantitative data analysis approach is chosen and two main methods are used: data study that aims to identify patterns and interesting relationships in the data, and a simulation study that uses real input data to attempt to ide

Greenhouse gas flux at a temperate peatland : a comparison of the eddy covariance method and the flux-gradient method

Northern peatlands have accumulated carbon for thousands of years and currently hold around one third of all soil carbon on earth. Large uncertainties are associated with predictions of how northern peatlands will react to climate change. This is because the cold, wet and anaerobic conditions lead to two opposing forces from a radiative forcing perspective – CO2 sequestration from photosynthesis b

Performance Measurement Systems in Tripartite Collaboration - Use and Perception in a Public Transportation Context

Title: Performance Measurement Systems in Tripartite Collaboration - Use and Perception in a Public Transportation Context Seminar date: 2025-06-05 Course: BUSN09 - Degree project in International Strategic Management Authors: Filip Milicic & Hedda Eld Supervisor: Magnus Johansson Keywords: Performance measurement systems; PMS; Tripartite Collaboration; Public Transport, Public Transportatio

How has the spatial distribution of mangroves changed in Busuanga municipality from 2020 to 2024?

Mangrove forests are highly productive and vital ecosystems within the tropical and subtropical latitudes. They are considered biodiversity hot spots and hosts ha vast variety of species, both terrestrial and marine, and they are also found to be one of the most productive carbon pools in the world. Mangroves additionally provide coastal communities with timber but also important shelter from tsun

Mvec15 schema 150115

SCHEMA 20110322 PRELIMINÄRT SCHEMA 2014-12-10 Schema för MVEC15 Miljö – politik och förvaltning, 15 hp vt 15 Kurstid: 2015-01-19 – 2015-03-22 Kursansvarig: Åsa Knaggård, 046-222 01 64, asa.knaggard@svet.lu.se Introduktion: Måndag, 19 januari 2015, 9.15-12.00 Lokal: Heden Lärare: Åsa Knaggård Roger Hildingsson Lokaler: Ekologihuset, Sölvegatan 37, Lund. Litteratur: Obligatorisk Carter, Neal, 2007.

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec15_schema_150115.doc - 2026-05-11

Molecular Subtypes Are Associated With Clinical Benefit in Cisplatin-Treated Metastatic Urothelial Cancer Patients

PURPOSE: Cisplatin-based combination chemotherapy (CHT) is standard of care in metastatic urothelial cancer (mUC); however, no predictive molecular biomarkers are available for clinical use. The aim of this study was to investigate the impact of molecular subtypes in relation to treatment response and survival in patients with mUC treated with first-line CHT.PATIENTS AND METHODS: Molecular subtype

Effectiveness and Safety of the ESC-TROP (European Society of Cardiology 0h/1h Troponin Rule-Out Protocol) Trial

BACKGROUND: European guidelines recommend the use of a 0h/1h hs-cTn (high-sensitivity cardiac troponin) protocol in patients with acute chest pain. We aimed to determine the performance of this protocol in routine care when supplemented with patient history and ECG and a recommendation to refrain from noninvasive testing in low-risk patients.METHODS AND RESULTS: This was a pre- and postimplementat