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Diverse organophosphate hydrolases have convergently evolved the ability to hydrolyse man-made organophosphates. Thus, these enzymes are attractive model systems for studying the factors shaping enzyme functional evolution. Methyl parathion hydrolase (MPH) is an enzyme from the metallo-β-lactamase superfamily, which hydrolyses a wide range of organophosphate, aryl ester and lactone substrates. In
In this paper we study the propagation problem of a time harmonic electromagnetic field inside a cavity filled with a generic bianisotropic medium. We define the concepts of eigenfrequencies and modes of the cavity and we propose a method to prove their existence and countability. We extend, in this respect, the theory for the isotropic, homogeneous, lossless cavity.
High resolution photoemission applied to the C 1s and Rh 3d core levels has been used to investigate the adsorption sites at low temperature of CO on the Rh(111) single crystal surface as a function of CO coverage. Two different sites are found to be occupied by the CO molecules. At coverages up to 0.5 monolayers the majority of the molecules are found to adsorb in on-top sites whereas at higher c
Abstract in ItalianQuesta esposizione propone in maniera teoretica una critica dell’esagerazione come approccio utile a qualsiasi filosofia che si occupi dei cosiddetti temi esistenziali. Si segue l’esempio dell’esagerazione per proporre un pensare oltre l’essere, in contrasto con la questione dell’essere senza esagerazione. Infine, si propone la critica propria dell’esagerazione come atteggiamentThis theoretical exposition proposes the critique of exaggeration as the approach to any philosophy that deals with the so-called existential themes. It provides the example of exaggeration in thinking beyond being in contrast to the question of being without exaggeration. Finally, it proposes the critique of exaggeration as a philosophical attitude that resists the temptation to seriously engage
The Ezrin/Radixin/Moesin (ERM) family of proteins act as cross-linkers between the plasma membrane and the actin cytoskeleton. This mechanism plays an essential role in processes related to membrane remodeling and organization, such as cell polarization, morphogenesis and adhesion, as well as in membrane protein trafficking and signaling pathways. For several human aquaporin (AQP) isoforms, an int
Within a collaboration between MAX-lab and BESSY a one stage seeded HGHG-FEL has been set up at Maxlab. BESSY has built the undulator system consisting of a modulator, a radiator and an electromagnetic chicane. BESSY has also installed three types of diagnostic tools: optical fibres for a fast Cherenkov beam loss detection, optical fibres for absolute dose measurements via their radiation-induced
Food is one of the most traded goods, and the conflict in Ukraine, one of the European breadbaskets, has triggered a significant additional disruption in the global food supply chains after the COVID-19 impact. The disruption to food output, supply chains, availability, and affordability could have a long-standing impact. As a result, the availability and supply of a wide range of food raw materia
Multivariate random sums appear in many scientific fields, most notably in actuarial science, where they model both the number of claims and their sizes. Unfortunately, they pose severe inferential problems. For example, their density function is analytically intractable, in the general case, thus preventing likelihood inference. In this paper, we address the problem by the method of moments, unde
Resilience and gender have become new buzzwords for expressing renewal in peacebuilding. This article unpacks the gender-resilience nexus in theory and analyses global trends and variation in peacebuilding policy and practice. It advances an analytical framework based on three central pillars of peacebuilding: process, outcome, and expertise. A comprehensive analysis of 49 international peacebuild
Building on the base of the existing telescopes of the Event Horizon Telescope (EHT) and ALMA, the next-generation EHT (ngEHT) aspires to deploy ∼10 more stations. The ngEHT targets an angular resolution of ∼15 microarcseconds. This resolution is achieved using Very Long Baseline Interferometry (VLBI) at the shortest radio wavelengths ∼1 mm. The Submillimeter Array (SMA) is both a standalone radio
This master thesis maps and discusses the current and future needs, wishes and challenges of office workers. The resultant contextual knowledge is utilized to develop a concept of an office chair. The work followed an exploratory design process. Initially, literature and data on various topics were researched to form an understanding of the current and future working conditions of office workers.
This thesis primarily concerns the European Union (EU) value added tax (VAT) exemption for insurance transactions. Due to the negative consequences that exemptions have on the proper functioning of the VAT system and those subject to it, this thesis explores the possibility of adopting the Kiwi taxed approach for insurance transactions. In order to do this, the provisions and functioning of both t
Lauded for its success and heralded as an economic model for peripheral European countries to follow, since the bursting of the Irish property bubble in 2008 the management of the Celtic Tiger by the Irish state has been castigated as expressively how not to manage an economic bubble. Following a decade and a half of continuous growth averaging over six per cent, the Irish economy has since experi
Housing expenditure is without doubt one of the biggest expenditure posts for all households. By using econometrics to estimate regressions with cross-‐sectional data including more than 1500 individuals, this thesis examines whether there is any individual characteristics that determines how big a share of the disposable income that is spent on housing each month. The results indicate that diffe
Forest biomass used in bioenergy systems, is a proven, large scale, cost-effective and growing renewable energy source in numerous countries. In Australia, the technical potential and environmental benefits of forest biomass for energy purposes are evident to many social and market actors, yet implementation is minimal. This work investigates a number of the underlying factors for the low implemen
