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Oxytocin (OT) and vasopressin (VP) are neurohypophyseal hormones with potent stimulatory actions on the uterus. In order to determine whether these hormones may have a paracrine action on the uterus, OT and VP gene expression was studied in myometrium from pregnant rats at gestational ages of 14 and 20 days, and from ovariectomized animals treated with oestradiol and progesterone. OT and VP mRNA c
Den svenska arbetskraften har blivit äldre under 1900-talet. Under vissa perioder har denna åldrandeprocess accelererat, medan den har avtagit under andra perioder. I denna studie undersöks vilken roll dessa förändringar i åldersstrukturen spelar för genomsnittlig arbetsproduktivitet och ekonomisk tillväxt. Olika åldersgrupper besitter olika typer av humankapital, eftersom den individuella produktIn the 1900s the Swedish labour force underwent an ageing process, accentuated in some periods and stagnant in others. This study inquires into how, and to what extent, these demographic shifts in the labour market explain changes in average labour productivity and economic growth. Different age groups possess different types of human capital, leading to changes in individual productivity over the
Understanding how sensory information is used by motor systems for motor commands requires detailed knowledge about how the body shape and biomechanics are represented in the motor circuits. We have used the withdrawal reflex system as a model for studies of sensorimotor transformation. This system has a modular organisation in the adult. Each module performs a detailed and functionally adapted se
PURPOSE: Urinary proteomics has become a key discipline within clinical proteomics for noninvasive diagnosis and monitoring of disease, and biomarker discovery. In order to decipher complex proteomes, high demands will, however, be placed upon the methodology applied. The purpose of this study was to develop a recombinant antibody microarray platform for urinary proteomics. EXPERIMENTAL DESIGN: W
Soil is a dynamic system in which microorganisms perform important tasks in organic matter transformations and nutrient cycles. Recently, some studies have started to focus on soil metaproteomics as a tool for understanding the function and the role of members of the microbial community. The aim of our work was to provide a review of soil proteomics by looking at the methodologies used in order to
Background: Symptoms associated with primary headaches are linked to cranial vascular activity and to the central nervous system (CNS). Review: The central projections of sensory nerves from three cranial vessels are described in order to further understand pain mechanisms involved in primary headaches. Tracers that label small and large calibre primary afferent fibres revealed similar distributio
BACKGROUND AND PURPOSE: Preeclampsia is a major obstetric problem of unknown etiology. The fact that removal of the placenta is the only cure for preeclampsia, has led to the well-established hypothesis, that the placenta is central in the etiology. Gene profiling and proteomics studies have suggested oxidative stress caused by reperfusion and free oxygen radicals as a potential pathophysiological
In this thesis, theoretical models are applied to study some aspects of intrinsically disordered proteins, i.e. proteins that partly or entirely lack a stable native structure. In particular, focus is on peptide binding and aggregation. Knowledge about these mechanisms is important for understanding how proteins interact with each other and how mutations can affect the function and sometimes give
This thesis contains six papers dealing with different aspects of damage and fracture in paper. The work addresses the problem of material length scales in the context of deformation and fracture of paper materials. In Paper 1, localised failure in low-basis weight paper is studied and a fracture model based on continuum damage mechanics is presented. A gradient enhanced theory is used that incorp
Abstract in UndeterminedCompanies in the food industry are driven to improve their traceability for several reasons. The primary reasons are food safety and quality. Another is the response to the increased interest among consumers in imperceptible product attributes such as organic, fair trade, dolphin-safe and non genetically modified (non-GMO). Such attributes are hard to distinguish and thus r
SUMMARY Torsten Weimarck: ACADEMY AND ANATOMY. On the History of the Human Body in Art Instruction and Studio Practice from ca. 1600 up to ca. 1810, with Particular Emphasis on the Instruction of Anatomy at the Academies of Art in Stockholm and Copenhagen The aim of the present study is to contribute to the documentation and interpretation of the image and experience of the body by means of t
Popular Abstract in Swedish Jag har i den här avhandlingen behandlat problemställningar inom tre olika områden inom astronomin. Det som sammanlänkar dessa är att alla innefattar dubbelstjärnor där avståndet mellan stjärnorna är litet, dvs de har en kort period. De är också alla datorsimuleringar. Jag har satt upp en modell för att betrakta de astronomiska systemen och genom numeriska metoder beräkThis thesis introduces and summarizes four papers dealing with computer simulations of astrophysical processes involving binaries. The first part gives the rational and theoretical background to these papers. In paper I and II a statistical approach to studying eclipsing binaries is described. By using population synthesis models for binaries the probabilities for eclipses are calculated for diff
Stylistic Fronting (SF) is a process that fronts various types of non-subjects to the preverbal position in subjectless clauses (“that gone have”, etc.). With the exception of Icelandic and to some extent Faroese, SF has disappeared from Scandinavian varieties. It is commonly assumed that even in Icelandic it is formal and old fashioned, indicating that it might be on its way out of this language
Popular Abstract in Swedish Hudfibros, inre organengagemang och autoantikroppar vid systemisk skleros: longitudinell utveckling och effekt på överlevnad. Systemisk skleros kallas ofta för sklerodermi. Sjukdomen tillhör de systemiska bindvävssjukdomarna och handläggs i Sverige oftast av reumatologer. Kardinalsymtomet vid sklerodermi är förhårdnad hud vilket gett sjukdomen den dess namn. Sklero betySystemic sclerosis (SSc) is a connective tissue disease with a highly variable prognosis. Since new treatment strategies are emerging, there is a need for prognostic markers in order to help allocate patients to the optimal treatment. When comparison is made to the general population, there is an increased mortality rate in this study, both in the series as a whole and in the subgroups of men and
Purpose of this paper The purpose of this paper is to present a comparative case study of the procedures and guiding principles in the packaging selection practice of two international companies. Design/methodology/approach A qualitative case study with an inductive approach was conducted. The data was collected through semi-structured interviews, documentation, and field visits. Findings Th
Researchers who desire to bring about change in organizational settings require approaches to inquiry which can go beyond superficial appearances and prejudice. In seeking to go beyond mere examination of socio technical systems researchers have developed a proliferation of different approaches. Many of these have drawn upon social and human sciences to ground methods and assumptions in philosophi
Popular Abstract in Swedish I början av 1980-talet rökte ungefär var tredje gravid kvinna i Sverige. Detta innebar att rökning under graviditet var lika vanligt förekommande som rökning bland den vuxna befolkningen i övrigt. Sedan dess har rökningen bland gravida minskat markant och idag är det ungefär 10-12% som röker vid inskrivningen på mödravårdscentralen. Rökning under graviditet är en av deA smoking cessation program targeting pregnant women and their partners was monitored during 17 years and subjected to several substudies. All women in Blekinge, who gave birth in the months of September during the period 1984 to 2000, were asked to fill out a questionnaire, anonymously, about their smoking habits before and during pregnancy. During these years a long-term educational programme co
A common way to cool the tip is to use serpentine passages with 180-deg turn under the blade tip-cap. Improving internal convective cooling is therefore required to increase the blade tip life. In this paper, augmented heat transfer of a blade tip has been investigated numerically. The computational models consist of a two-pass channel with 180-deg turn and pin-fins mounted on the tip-cap, and a s
