Filtyp
SUMMARY: Antibody repertoires reveal insights into the biology of the adaptive immune system and empower diagnostics and therapeutics. There are currently multiple tools available for the annotation of antibody sequences. All downstream analyses such as choosing lead drug candidates depend on the correct annotation of these sequences; however, a thorough comparison of the performance of these tool
The compelling images and promises attached to autonomous drive vehicles can easily create an impression that one can speak of a radical distinction between a self-driving future and a manual-driving present. Yet today’s drivers can already refer to their everyday driving as being experienced as though on ‘auto-pilot’, in which they are able to drive their cars while lost in things such as daydrea
Water resources are under increasing pressure, and there are tensions between increasing demand and the natural limits to potable water supply. Authorities must find solutions that fulfil societal demands without compromising environmental integrity. As one way to counteract water deficits, desalination has evolved as an attractive solution. This technology is contested and associated with a varie
Background: Data commentary, in-text comments on the visual presentation of data, is acknowledged as a central aspect of academic writing in many engineering disciplines. At the same time, it is a feature that it has been shown to be challenging for students. One of the genres in which data commentary plays a significant role in many engineering disciplines is the master’s thesis. Comparatively li
The traditional view of the planktonic food web describes consumption of inorganic nutrients by photoautotrophic phytoplankton, which in turn supports zooplankton and ultimately higher trophic levels. Pathways centred on bacteria provide mechanisms for nutrient recycling. This structure lies at the foundation of most models used to explore biogeochemical cycling, functioning of the biological pump
Background: Shape coexistence in heavy nuclei poses a strong challenge to state-of-the-art nuclear models, where several competing shape minima are found close to the ground state. A classic region for investigating this phenomenon is in the region around Z = 82 and the neutron midshell at N = 104. Purpose: Evidence for shape coexistence has been inferred from a-decay measurements, laser spectrosc
The impact of sample crushing on the detected porosity of hardened cement pastes by low temperature calorimetry (LTC) was studied using powder and cylinder samples. Two types of cements, CEM I and CEM III were used to prepare the pastes. A model porous material, MCM-41, was also used in order to investigate some aspects of the measurement and the evaluation approach. The powder and cylinder sample
Basidiomycota fungi in the order Polyporales are specified to decomposition of dead wood and woody debris and thereby are crucial players in the degradation of organic matter and cycling of carbon in the forest ecosystems. Polyporales wood-decaying species comprise both white rot and brown rot fungi, based on their mode of wood decay. While the white rot fungi are able to attack and decompose all
Simple roles for photoreception are likely to have preceded more demanding ones such as vision. The driving force behind this evolution is the improvement and elaboration of animal behaviors using photoreceptor input. Because the basic role for all senses aimed at the external world is to guide behavior, we argue here that understanding this "behavioral drive" is essential for unraveling the evolu
For memory retrieval, pattern completion is a crucial process that restores memories from partial or degraded cues. Neurocognitive aging models suggest that the aged memory system is biased toward pattern completion, resulting in a behavioral preference for retrieval over encoding of memories. Here, we built on our previously developed behavioral recognition memory paradigm—the Memory Image Comple
Rapid and reliable observations of soil electrical conductivity are essential in order to maintain sustainable irrigated agriculture. Direct measurement of the electrical conductivity of saturated soil paste (ECe), however, is tedious andtime consuming. Therefore, there are needs to find efficient indirect methods to predict the soil salinity from other readily available observations. In this pape
The anaerobic bacterium Finegoldia magna is part of the human commensal microbiota, but is also an important opportunistic pathogen. This bacterium expresses a subtilisin-like serine-proteinase, SufA, which partially degrade the antibacterial chemokine MIG/CXCL9. Here, we show that MIG/CXCL9 is produced by human keratinocytes in response to inflammatory stimuli. In contrast to the virulent human p
The observation that neural grafts can induce dyskinesias has severely hindered the development of a transplantation therapy for Parkinson's disease (PD). We addressed the hypothesis that inflammatory responses within and around an intrastriatal graft containing dopamine neurons can trigger dyskinetic behaviors. We subjected rats to unilateral nigrostriatal lesions with 6-hydroxydopamine (6-OHDA)
This PhD thesis is made up of five independent studies and a comprehensive synthesis. The first three studies are published 2001 in the book Vem behöver en by? Kyrkheddinge, struktur och strategi under tusen år (pp. 1-95) (Who needs a village? Kyrkheddinge, Structure and Strategy During a Thousand Years). The remaining two parts and the synthesis are published in the volume Den medeltida byns soci
Aims: Respondent-driven sampling is a research technique, new to the Scandinavian setting, used in hard-to-reach populations, such as subjects at risk for HIV, including drug users. This study aimed to evaluate the use of respondent-driven sampling originating from syringe exchange clients, as a method to identify 'hidden' drug users without treatment or social service contact. Methods: Nine heroi
Wind power is seen by many observers as an important part of the transition to a sustainable energy system, since it does not contribute to the environmental problems connected with dominating energy forms such as fossil fuel, nuclear power and large-scale hydro power. At the same time wind power has some characteristics that makes it a special challenge for land use planning. In Sweden, where win
Purpose: Sick leave and unemployment are highly prevalent among people with affective disorders. Their depression severity is disabling and inversely related to having employment. No evidence-based vocational rehabilitation exists for this target group. Knowledge is therefore needed to understand the psychosocial factors that affect depression severity in order to develop new rehabilitation interv
The present thesis explores Japanese imperative constructions from a general linguistic perspective, as well as examining the imperative as a cross-linguistic object of study. On the definitional side, a terminological apparatus for the description and analysis of imperatives and directives is presented. It includes the proposal that the range of conventional directive strategies in a language be
To meet the needs of an increasing, heterogeneous, ageing population it is imperative to understand links between home and health. In Latvia, only limited research targeting the health and home situation of very old people is available. Consequently, the aim of this study was to describe how the home environment and aspects of health have changed over nine years between 2002 and 2011 for very old
