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Complement is a cascade-like system that is part of the innate immune defence. It is an explosive system, potentially harmful also for the host cells, and needs to be strictly regulated. An important down-regulator of complement is C4b-binding protein (C4BP). C4BP contains two different types of subunits, seven identical a-chains and one unique P-chain. The alpha-chains bind to C4b, C4BP's target

BACKGROUND: Situational needs of health care facilities inform the optimal allocation of resources and quality improvement efforts. This study examines surgical care delivery metrics at a tertiary care institution in Liberia. METHODS: We retrospectively reviewed operative and ward logbooks from January 1 to December 31, 2012. Data parameters included patients' age, diagnosis, procedure, mortality,

Sulfur-containing compounds are used as rescue agents to protect normal tissue from the toxic side effects of cis-[PtCl2(NH3)(2)] (cisplatin) without affecting its anti-tumour activity. Reactions of the model complexes [Pt(dien)Cl](+) (1) and [Pt(dien)(GSMe)](2+) (2) (GSMe = S-methylglutathione) with the rescue agents glutathione (GSH), thiourea, thiosulfate, and diethyldithiocarbamate (DDTC) have

In Sweden, municipalities organize a large share of public services but the conditions for providing these services differ considerably due to differences in size and wealth. In the wake of financial stress and New Public Management reforms the Swedish local governments seeks new ways to make both ends meet and still manage the services to be in line with the present (not the past) demands of the

Popular Abstract in Swedish Avhandlingen utreder några av konsekvenserna av de institutionella reformer som genomfördes i Sydafrika under 1990-talet, med särskilt fokus på det nya kommunsystemet, enligt vilket varje kommun är skyldig att stimulera lokal ekonomisk utveckling i samarbete med det lokal näringslivet och andra civilsamhälleliga aktörer. Den syftar även till att utveckla den samhällsvetThis thesis focuses on the consequences of the institutional transformations in South Africa during the 1990s with specific reference to the introduction of a mode of local governance based on the direct participation of private and civic actors in policymaking and implementation. The study also aims to contribute to theory. The approach is that public, private and civic associations are best unde

Aim: Several studies have addressed the association between changes in the female sex hormones estrogen and progesterone levels and changes in parameters of periodontitis. In order to understand how these hormones affect periodontal health it is of major importance to obtain information on their physiological importance. We have previously shown that periodontal ligament cells (PDL cells) express

BACKGROUND: Consumption of soluble dietary fibre is correlated with decreased postprandial glucose and insulin responses and hence has beneficial effects on the metabolic syndrome. AIM OF THE STUDY: To investigate the effects on postprandial glucose, insulin and triglyceride concentrations of meals enriched with soluble dietary fibres from oats, rye bran, sugar beet fibre or a mixture of these thr

Syftet med uppsatsen är att genom en rättsdogmatisk metod och ett kritiskt perspektiv granska hur underlåtenhet påverkar bedömningen av straffvärdet i en domstols straffmätning och undersöka om underlåtenhet verkligen ska ses som en förmildrande omständighet. Uppsatsen behandlar själva utformningen av principerna kring underlåtenhetsbrott enligt Jareborgs garantlära i svensk rätt idag och en utredThe purpose of this essay is to use a legal dogmatic method, and with a critical perspective, analyse how the fact that a crime is one of omission, thus caused by a failure to act, affects the Court's judgement on a suitable sentence. Is the fact that a crime is an omission automatically a mitigating factor that leads to a lesser sentence? This essay treats the general legal principles and the

Background Lagoons are shallow coastal water bodies which occupy 13 % of the world’s total coastlines. Healthy lagoons have a rich aquatic fauna and can provide an economic benefit for the people living in its vicinity. Due to anthropogenic activities, the water quality in many lagoons is deteriorating. The Mundaú-Manguaba Estuarine-Lagoon System is no exception. BOD-rich water from the nearby sug

Background: Since 1994 the need for joint sexual and reproductive health (SRH) responsibility between men and women to achieve gender equality and reduce health inequalities has received more attention. The focus has been on young people as they transition into adulthood and are vulnerable to the negative consequences of early pregnancy and childbirth, STIs and early parenthood. Traditionally, con

Anammox-processen erbjuder en hållbar och energieffektiv metod för biologisk kväve-avskiljning inom avloppsrening. Men bakterierna som utför arbetet kväver en källa till nitrit, och en möjlig lösning på detta är att kombinera metoden med partiell denitrifikation. Kan ett samarbete mellan dessa olika grupper av mikroorganismer upprättas, och vilken påverkan har typen av kolkälla som används i proceIn traditional wastewater treatment, nitrogen is removed through the biological process combination of nitrification and denitrification. Although it is a well-established method, the need for aeration and possible addition of an external carbon source results in it being an energy-negative and costly process, thus making alternative methods for nitrogen removal compelling to examine. Anaerobic am

Egyptology in the 19th and early 20th centuries developed simultaneously with increased imperial presence in Egypt by the European imperial powers, which would have influence on how the discipline was practised. The history of Egyptology has for this reason primarily focused on the big four – Great Britain, France, Germany and USA – and on Egypt itself. The aim of this study is to examine how Egyp

Issue of study: The starting point for innovation is ideas, which can be seen as fuel to the innovation process as it supplies the innovation funnel with new or improved concepts that finally may spark innovation. There is a vast literature on the success of a few radical ideation methods and the use of creativity tools, while few have dealt with the use and effects of ideation approaches in pract

Public space are open spaces and areas where people in the city move around, get together and play, regardless of background, age, ethnicity, gender and income. This is particularly important in poor neighborhoods where people have no access to places where to socialize. Well designed and planned public spaces are symbols of several important aspects of a city; health, safety, culture and local ec

Individualization of Children: A Critical Discourse Study of Childrens' Competence in Public Texts on Social Care of Children The aim of this study is to critically examine and discuss overarching notions and discourses on children and individualization, with a starting point in public texts within the field of social work with children. The empirical material has been two SOU-reports (“Swedi

Värdering av obebyggd tomtmark för småhus kan ibland vara svårt då det saknas ett bra ortsprismaterial. Ännu svårare är att värdera tomtmark för småhus som är bebyggda med byggnader på ofri grund. Tomtmark med byggnader på ofri grund upplåtna med nyttjanderätter anses ha ett lägre värde än tomtmark som är obebyggd eller tomtmark som är bebyggd av fastighetens ägare. Det beror på att nyttjanderätteThe objective of this work is to examine the impact on value that a house on leasehold has on the underlying land in a partition ordinance. In order to build a foundation and create an understanding about houses on leasehold, partitiontools and different methods of valuation I undertook literature studies. The literature consisted of, among other things, preparatory work for FBL and the Court of A

The area management responsible for the United Kingdom, Ireland, and the Nordic region within the Company expressed a desire to identify new business opportunities in the Nordic region. The motive was to use the identified opportunities as an argument for additional resource allocation to the Nordic region. In previous years, the Company has performed a number of projects focused on identifying op

Titel: Diskonteringsräntan vid nedskrivning av goodwill - En jämförelsestudie av marknadsmässiga bedömningar Seminariedatum: 2014-05-23 Ämne/kurs: FEKN90, Företagsekonomi: Examensarbete i Corporate Finance på magisternivå. 30hp. Författare: Victor Håkansson och Anton Persson Handledare: Erling Green Nyckelord: Goodwill, nedskrivningsprövning, diskonteringsränta, marknadsmässiga bedömningar ocTitle: The discount rate used in the impairment testing of goodwill – A comparison of market-based assessments Seminar date: 2014-05-23 Course: FEKN90, Business Administration: Master Thesis in Corporate Finance, 30 HP Authors: Victor Håkansson and Anton Persson Advisor: Erling Green Key words: Goodwill, impairment testing, discount rate, market-based assessments and IAS 36. Purpose: The pur

Perovskitsolceller har blivit ett populärt forskningsområde eftersom de har haft en exceptionellt snabb utveckling i verkningsgrad under de senaste åren. Trots att perovskitbaserade solceller nu har nått verkningsgrader jämförbara med kiselsolceller, så återstår flera utmaningar för att möta solcellsmarknadens förväntningar för de applikationer där man hoppas att perovskiterna ska komplettera kiseOver the last few years there has been a steady increase in interest in the exploration of perovskite materials within photovoltaic research. This can to a large extent be attributed to the incredible pace at which solar cells based on perovskites have improved in efficiency during the same time period. Perovskite solar cells (SCs) are not only an alternative to today’s market leading silicon base

GABAergic Neurotrasmission – A “cross-talker” between inflammation and neural plasticity in stroke Stroke is a leading cause of disability and no pharmacological treatment is currently available to promote recovery in suffering patients. A major part of research is focusing on finding new biological targets which can be pharmacologically intervened with, providing favorable results in facilitatin