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Biosynthesis, Processing, and Sorting of Human Neutrophil Granule Proteins. Focus on Cathepsin G, Proteinase 3, and Azurocidin

Popular Abstract in Swedish Bildning, bearbetning och upplagring av cathepsin G, proteinas 3 och azurocidin - närbesläktade bakteriedödande proteiner i vita blodkroppar Människans kropp utsätts dagligen för fientliga attacker av olika sorters mikroorganismer, tillhörande bakterie-, virus- eller svampsläktet. Så länge vi är friska och vårt immunförsvar fungerar, kan vi som tur är framgångsrikt fö

Computational Analysis and Modeling Techniques for Monolithic Membrane Reactors Related to CO2 Free Power Processes

Funded by European Community and Swiss government research project AZEP (Advanced Zero Emission Power Plant), the project was carried out at the Department of Energy Sciences at Lund Faculty of Engineering (LTH). The project addressed the development of a specific, zero emissions, gas turbine-based, power generation process to reduce local and global emissions in a cost-effective way. In this proj

Improving Procurement Performance with E-business Mechanisms

E-procurement — e-business mechanisms deployed on procurement — offers many recent and innovative methods that can improve procurement in different ways. The key challenge of e-procurement, however, is how to apply the various e-procurement applications in such a way that they improve the procurement practice and sourcing strategy of a company. There is a demand for an investigation that scrutiniz

Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity

Popular Abstract in Swedish Bakgrund: Diabetes är en sjukdom som karakteriseras av kroniskt förhöjt blodsocker och som obehandlad kan leda till svåra komplikationer i blodkärl, ögon, njurar, nerver m.m. Sjukdomen beror på kroppens oförmåga att producera (typ 1 diabetes) eller svara på effekt av (typ 2 diabetes) hormonet insulin. Det finns ca 150 miljoner personer med diabetes i världen idag, och sType 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. In order to characterise the metabolic defects in various stages of glucose tolerance, the insulin sensitivity and insulin secretion was measured in a large population based study in Finland and

Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs.

Popular Abstract in Swedish Ateroskleros är en sjukdomsprocess vars grundläggande utveckling i blodkärlens väggar sannolikt börjar flera decennier innan insjuknandet i infarkt eller slaganfall inträffar. Som svar på endotelskada, inflammatoriska mediatorer eller tillväxtfaktorer i kärlet kommer glatta muskelceller att dela sig, migrera in mot blodbanan och börja syntetisera en helt ny uppsättning Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. The conversion of the SMC to this role is marked by a modulation from contracti

Understanding the spreadsheets use in budgeting

This paper explores the use of spreadsheets in budgeting in order to explain how and why spreadsheets are used or not used in budgeting practice. Guided by modern budgeting research, budgeting is considered as a social phenomenon which requires flexibility for decision-making and integration for management control. Twenty-one interviews with business controllers in eleven leading for-profit organi

Mechanisms of insulin exocytosis and release

Popular Abstract in Swedish Insulin frisätts från B-cellerna i bukspottkörteln (pankreas) när blodsockerhalten ökar över den normala (80-100 mg per dl), exempelvis efter en kolhydrat- och sockerrik måltid. Medan ?friska? B-celler har förmågan att reagera kraftigt redan på små (10%) förändringar i blodsockerhalten, så utvecklar ?ålders-diabetiska? B-celler en blodsockerblindhet och insulinfrisättniEndocrine cells as well as neurons release their hormones and transmitters by regulated exocytosis. In the pancreatic B-cell, stimuli like glucose initiate biochemical and electrical processes that culminate in influx of Ca2+, which then triggers exocytosis of insulin-containing granules. Fusion of the secretory vesicles occurs rapidly upon Ca2+-influx but requires a granule to be ?primed? by an A

Att se stjärnor på ljusa dagen. Förvandling och försoning i August Strindbergs En blå bok

Abstract Regnell, Astrid: Att se stjärnor på ljusa dagen. Förvandling och försoning i August Strindbergs En blå bok. Seeing stars in broad daylight. Transformation and Reconciliation in August Strindberg’s Zones of the Spirit. In this thesis a pattern of coherence is explored in August Strindberg’s Zones of the Spirit (En blå bok) – a literary work consisting of a collection of short and quite div

Tajnees - Recruiting loyal subjects in Bahrain

This paper is part of an ongoing research on the trajectory of rhetoric of political reforms in Bahrain during the past 10-years of reign by king Hamad bin Isa. Within less than two years of his reign, the king abandoned his wide ranging blueprints for political and institutional reforms designed to end to a decade-long civil unrest. I argue that the king continues to use, albeit more creatively,

Subjective Outcomes after Knee Arthroplasty

Outcome questionnaires are increasingly being established as a validated mode of acquiring unbiased information on the results after health interventions. Using an assortment of questionnaires, distributed by mail to 27 372 and to a subgroup of 3 600 patients on file in the Swedish Knee Arthroplasty register (SKAR), relevant questionnaires were found to represent a feasable means of acquiring info

Differential gene expression analysis of placentas with increased vascular resistance and pre-eclampsia using whole-genome microarrays.

Pre-eclampsia is a pregnancy complication characterized by hypertension and proteinuria. There are several factors associated with an increased risk of developing pre-eclampsia, one of which is increased uterine artery resistance, referred to as "notching". However, some women do not progress into pre-eclampsia whereas others may have a higher risk of doing so. The placenta, central in pre-eclamps

Mellan det förflutna och framtiden : Den sandinistiska revolutionen i Nicaragua

The theme throughout this book is the buildning up of a new societal structure and the conflicts encompassed in such a project. I discuss the societal changes in Sandinista Nicaragua by way of placing the revolution in a historic, political, and social context. Throughout the work process it became increasingly clear that the conflicts of the FSLN were in principal due to two factors. First, the F

Knowledge Representation for Learning How to Evaluate Partial Plans

In this paper we present some ideas for knowledge representation formalism suitable for rational agents which learn how to choose the best conditional, partial plan in any given situation. In our architecture, the agent uses an incomplete symbolic inference engine, employing Active Logic, to reason about consequences of performing actions — including information-providing ones. It utilises a simpl

Den politiska stjärnan : en annorlunda teoretisk uppsats om övergången från teatermetaforen till filmmetaforen

Den som vill göra det lätt för sig och slippa läsa en uppsats väntar sig därmed med all rätt en trevlig sammanfattning av dess innehåll. Och det är just en sådan ni håller framför er i er hand. Denna uppsats är ett par första trevande steg till att skapa en dialog, förvisso för vissa kanske en aning osystematisk och väldigt personligt. Men det är likväl en inbjudan till deltagande, till samtycke o

Brands Transfer of Meaning: An analysis of brands roles within product placement

Thesis purpose: The purpose of this thesis is to make a contribution, by connecting the transfer of meaning within the context of TV series. The meaning is transferred from the brand to the character in a TV series and then further to the viewer. To look at different role functions that are used in dramaturgy and narrative techniques, we will be able to see how the brand will have a specific role

Climate change mitigation and energy efficiency: challenges in the wastewater sector

The wastewater sector provides water sanitation to populations in order to preserve humanhealth and the natural environment. In developed countries, due among others to increasingpressures coming from climate change and population growth, the wastewater treatment isaffected and needs to adapt to such changes. As a result, effluent requirements arebecoming more stringent, nutrients and organic remo

Free and green. The effect of decoupling CAP on emissions.

The Common Agricultural Policy is one of the most important policies within the European Union. However, the support from CAP have had some unexpected consequences for the environment. Major changes were made in 2003 regarding the way payments were given to farmers, in order to reduce the environmental impact of agricultural production. The support was made decoupled, which basically meant a great

Strategiskt förändringsledarskap: case inköp

Background: Many companies are today struggling to keep up with the challenges that have arisen from the increase of globalization and harder competition during the last couple of decades. This might reflect on companies as they need to do a strategic organizational change in order to create or retain a competitive position on the market. Those kind of change projects are usually difficult to

MRI only radiotherapy using synthetic CT images: Dosimetric accuracy and patient positioning strategies in an MRI only workflow

Sedan sent 1800-tal har strålterapi använts för behandling av cancer. 50% av alla cancerpatienter blir någon gång behandlade med strålterapi, som är en avancerad teknik med många olika steg för att uppnå den slutgiltiga behandlingsplanen. Patienten börjar sin strålbehandlingsresa med att bli diagnosticerad och får sin behandling ordinerad. Efter detta startar förberedelserna inför strålbehandlingeBackground and purpose: Magnetic resonance imaging (MRI) only radiotherapy has, due to superior soft tissue contrast of MRI and the possible reduction of systematic uncertainties, grown into a promising technique. The purpose of this work is to investigate parts of an MRI only workflow with synthetic computed tomography (sCT) images generated from MRI. This was done through investigation of treatm

Identifying critical service issues in the service encounter – a first step in the development of a conceptual model for the shipping industry

Title Identifying critical service issues in the service encounter – a first step in the development of a conceptual for the shipping industry Author Claas Boomgaarden Key Words Service Quality, Service Encounter, SERVQUAL, INDSERV, PDSQ, LSQM, Shipping Industry, Service Science, Service Dominant Logic, Relationship Marketing Purpose The purpose of this research is to provide a first step in th