Filtyp
For the Phase-II Upgrade of the ATLAS Detector [1], its Inner Detector, consisting of silicon pixel, silicon strip and transition radiation sub-detectors, will be replaced with an all new 100% silicon tracker, composed of a pixel tracker at inner radii and a strip tracker at outer radii. The future ATLAS strip tracker will include 11,000 silicon sensor modules in the central region (barrel) and 7,
Lipoproteins play a central role in the development of atherosclerosis. High and low-density lipoproteins (HDL and LDL), known as ‘good’ and ‘bad’ cholesterol, respectively, remove and/or deposit lipids into the artery wall. Hence, insight into lipid exchange processes between lipoproteins and cell membranes is of particular importance in understanding the onset and development of cardiovascular d
This talk describes the various stages of ATLAS Data Challenge 2 (DC2) in what concerns usage of resources deployed via NorduGrid's Advanced Resource Connector (ARC). It also describes the integration of these resources with the ATLAS production system using the Dulcinea executor. ATLAS Data Challenge 2 (DC2), run in 2004, was designed to be a step forward in the distributed data processing. In p
Popular Abstract in Swedish Visst har väl vi väl alla någon gång funderat på vårt ursprung. Hur såg vi ut innan vi blev människor? Såg mina förfäder ut som jag eller var de håriga över hela kroppen? Är vi kanske kusiner med schimpanserna eller är våra närmaste ap-släktingar små silkesapor? Visst är detta intressanta frågor, men har du någonsin funderat på hur våra förfäder såg ut för ännu längre sFishes (Superclass Pisces) constitute the most numerous and morphologically diverse vertebrate group, yet only a small fraction of all molecular evolutionary studies concern piscine evolution. This thesis aims to investigate the vertebrate tree, through the analysis of mitochondrial (mt) DNA sequences. To this end the coding regions of the mt genome of a jawless fish, the hagfish (Myxine glutinosa
The present study is a philosophical reflection on Martin Buber´s concept, Existential Guilt. To be able to atone existential guilt you must, according to Buber, acknowledge, identify and confess your guilt, if possible, in front of the one you have harmed. The study highlights an area that Buber does not discuss; the area between the existential guilt process and the liberating experiences that B
We consider designing demodulators for linear vector channels that use reduced-size trellis descriptions for the received signal. We assume an iterative receiver and use interference cancellation (IC) with soft-information provided by an outer decoder to mitigate the signal part that is not covered by a reduced-size trellis description. In order to reach a trellis description, a linear filter is a
Fetma och typ 2 diabetes är stora folksjukdomar som ökar i rasande takt världen över. En gemensam nämnare för dessa sjukdomar är att de vävnader i kroppen som reglerar ämnesomsättningen, t.ex. fettvävnaden, förlorar känsligheten för hormonet insulin så att det inte längre fungerar normalt. Detta kallas insulinresistens och i min forskning undersöker jag hur kroppens fettvävnad fungerar för att förObesity, insulin resistance and type 2 diabetes (T2D) are metabolic diseases that increase rapidly in the modern society. The underlying mechanisms are complex and involve both environmental and genetic factors. Adipose tissue is an important organ for maintaining whole body energy homeostasis. In response to nutrient overload (as observed in obesity), adipocytes become hypertrophic and dysfunctio
In Sweden, as in other industrialised nations, occupational exposure limits are considered to be an important tool for chemical risk management, although many other factors also play a role in occupational safety and health management. The aim of this study was to investigate the role of occupational exposure limits in relation to information about, and the risk perception of, chemicals. An interv
The following paper is a compilation of the ongoing Swedish PhD-project “Multifunctional streets in the city - towards a more attractive city for all users and stakeholders”. In focus are arterial streets, i.e. highly multifunctional traffic environments characterized of conflicting functions, with an extensive mix of traffic modes, activities and interests. The aim of the project is to clarify an
Deterministic lateral displacement provides a novel and efficient technique for sorting micrometer-sized particles based on particle size. It is grounded on the principle that the paths associated with particles of different diameters, entrained in flow streaming through a periodic lattice of obstacles, are characterized by different deflection angles with respect to the average direction of the c
The incidence of narcolepsy type 1 (NT1) increased in Sweden following the 2009-2010 mass-vaccination with the influenza Pandemrix-vaccine. NT1 has been associated with Human leukocyte antigen (HLA) DQB1*06:02 but full high-resolution HLA-typing of all loci in vaccine-induced NT1 remains to be done. Therefore, here we performed HLA typing by sequencing HLA-DRB3, DRB4, DRB5, DRB1, DQA1, DQB1, DPA1
Background: Neuropathological studies have linked tau aggregates to neuronal loss. To describe the spatial distribution of neurofibrillary tangle pathology in post-mortem tissue, Braak staging has been used. The aim of this study was to examine in vivo associations between tau pathology, quantified with [18F]flortaucipir PET in regions corresponding to Braak stages, and atrophy across the Alzheime
In this study the aim was, through interviews, to disclose 13 nurses' personal knowledge about the patients, themselves, and care provision, using a phenomenological-hermeneutic analysing method. Caring for people with severe dementia meant an intertwined life world emanating from making and doing together and the delicate interpretative work that the care provision required. The intertwined life
The perennial herbaceous crop Arundo donax is a potential feedstock for second-generation bioethanol production. In the present work, two different process options were investigated for the conversion of two differently steam-pretreated batches of A. donax. The pretreated raw material was converted to ethanol with a xylose-consuming Saccharomyces cerevisiae strain, VTT C-10880, by applying either
The formation of amyloid fibrils by the intrinsically disordered protein alpha-synuclein is a hallmark of Parkinson disease. To characterize the microscopic steps in the mechanism of aggregation of this protein we have used in vitro aggregation assays in the presence of preformed seed fibrils to determine the molecular rate constant of fibril elongation under a range of different conditions. We sh
