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A Dynamic Capabilities Approach to Sustainable Business Model Innovation : A Case Study of the Swedish Architecture Industry
Firms today are facing changing conditions which they must respond to in order to maintain a sustained competitive advantage. To address this change, practitioners such as managers and executives of large firms look towards the concepts of Business Models and Business Model Innovation, as tools to devise and execute strategies to manage that change. This study will present an in-depth comparative
Development and evaluation of a deep learning based artificial intelligence for automatic identification of gold fiducial markers in an MRI-only prostate radiotherapy workflow
Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for both objectives. Multi-echo gradient echo (MEGRE) images have been utilized for manu
Plasticized Poly (lactic acid) Films - Preparation and Properties
The development of biodegradable polymers from renewable resources is of importance in order to prevent the depletion of fossil fuels and the increasing emissions of carbon dioxide to the atmosphere caused by the commodity plastics of today. However, to be able to replace these non-environmentally friendly materials, production costs of biodegradable polymers have to be decreased and their physica
Evaluation of anaerobic digestion post-treatment options using an integrated model-based approach
The objective of this paper is to present the main results of an engineering-research project dealing with model-based evaluation of waste streams treatment from a biotech company. This has been extensively done in domestic treatment systems, but is equally important, and with different challenges in industrial wastewater treatment. A new set of biological (activated sludge, anaerobic digestion),
Fractionation gives therapeutic benefit in animal model of [177Lu]Lu-PSMA-617 therapy of prostate cancer
BackgroundThe clinical standard practice of [177Lu]Lu-PSMA-617 therapy is a single injection per treatment cycle, with 6 weeks between cycles. While clinical schedules currently utilize single-bolus cycles, splitting a treatment cycle into multiple smaller injections has demonstrated benefits in other radionuclide therapies, preclinically and in clinical studies. Potential mechanisms for improved BackgroundThe clinical standard practice of [177Lu]Lu-PSMA-617 therapy is a single injection per treatment cycle, with 6 weeks between cycles. While clinical schedules currently utilize single-bolus cycles, splitting a treatment cycle into multiple smaller injections has demonstrated benefits in other radionuclide therapies, preclinically and in clinical studies. Potential mechanisms for improved
LABORATORY TESTING RELATED TO UNLOADING MODULUS OF SOFT CLAY
När jord avlastas kan denna svälla, något som kan ge tryck och således skador på konstruktionsdelar som har kontakt med den svällande jorden. Det är därför av stor vikt att ha kunskap om hur jorden beter sig vid avlastning och detta undersöks vanligtvis i geotekniska laboratorier. I detta examensarbete studerades svällningen av lera, erhållen från Göteborgområdet, som avlastas med hjälp av en modiThe unloading modulus, together with the permeability, are responsible for the swelling process of a soil that is subjected to unloading. Studies to examine the unloading modulus of clay has previously been performed and several relationships describing this parameter has hence been developed. The methods to study the unloading modulus has previously been both laboratory studies and field measurem
Starkaste lampan sällan den bästa – Vetenskap och Hälsa
Starkaste lampan sällan den bästa – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Starkaste lampan sällan den bästa 2014-02-14 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Colourbox Många av dagens operationssalar har felaktig belysning. Istället fö
https://www.vetenskaphalsa.se/starkaste-lampan-sallan-den-basta/ - 2026-05-22
Regulation of normal and cancer cells as a base for cell cycle-targeted therapy
Popular Abstract in Swedish De flesta cancerpatienter dör på grund av spridning av tumörceller till olika organ. Invasiv och metastaserande cancer svarar ofta inte på behandling och blir då i många fall dödlig. Leukemi är en elakartad sjukdom av blodceller, som påverkar blod-producerande organ. Den höga förekomsten av leukemi förekommer i äldre befolkningen och hos barn. Leukemi återfall och resiThe majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. Elevated expression of a cell cycle regulator cyclin A1 initiated leukemia
Pancreatic cancer – Influence of Tumour Microenvironment
Popular Abstract in Swedish Pankreascancer (cancer i bukspottkörteln) utgör fjärde orsak död i cancer. Det är den cancerform som har den dystraste prognosen av alla, med en 5-års överlevnad mindre än 6%. Sjukdomsrelaterade symptom uppträder ofta sent i förloppet och det saknas metoder för tidig diagnos varför de flesta av patienterna upptäckts i sent skede. Endast cirka 20 procent av patienterna kPancreatic cancer (PC) is the fourth leading cause of cancer-related deaths, with a 5-year survival less than 6%. It does not show any symptoms in its early stages, hence most (>85%) of the patients are diagnosed at late stage. At the time of diagnosis, metastases are frequently observed which make most patients unsuitable for curative surgical treatment and chemotherapy remains the only choice fo
Global Norms for Public Acceptance for Desalination and Water Ruse
Desalting technologies and fresh water production has been developed over the years, including primarily thermal and membrane processes. Five different types of desalination technology were studied and compared for long-term of use namely, thermal processes include multistage flash evaporation (MSF), multiple effect evaporation (ME), and vapor compression (VC) and membrane processes contain revers
The nervous system of box jellyfish: A surprisingly complex system in a simple animal
The four surprisingly complex visual sensory organs of cubomedusae, the rhopalia, contain each six eyes of four morphologically different types, two of which are camera-type eyes. This means that the evolutionary basal nervous system of cubomedusae must process the visual signals received from a total of 24 rhopalial eyes. Since the neuronal organization of the rhopalia is obscure, the role of the
Plant community assembly and biodiversity: a spatio-temporal perspective
Att forma sitt rum : fullskalemodellering i participatoriska designprocesser
Architects design work sometimes originates from a simplified view of human demands and needs, which may result in environments that do not fulfill the users requirements. This thesis refers to five different case studies where the affected users were involved in the creation of their dwellings or working environment. The issue of the thesis is that participatory design creates environments which
Kinetics and Mechanism of the Reaction between Tetrachloroaurate(III) and Tetraabromoaurate((III) and Thiocyanate
The kinetics and mechanism for the overall reaction (i) (X = Cl or Br) have been studied at 25.0 °C using stopped-flow spectrophotometry. 3[AuX4]–+ 7SCN–+ 4H2O → 3[Au(SCN)2]–+ HSO4–+ HCN + 12X–+ 6H+ (i) The reaction takes place in two kinetically well separated steps. The initial, rapid process can be identified as stepwise ligand substitutions (ii) (n= 0–3) which take place via direct ligand disp
Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA
Rectal Cancer - Tumor Biology and Prognostic Markers
Popular Abstract in Swedish Cancer i tjock- och ändtarm drabbar årligen drygt 5000 svenskar. En rad faktorer har satts i samband med tumöruppkomst i tarmen, bl a ärftlighet, inflammatorisk tarmsjukdom, kost och motion, men det är till stor del okänt hur dessa faktorer orsakar cancerutveckling. Genetiska förändringar styr tumörutvecklingen Tumörerna utvecklas oftast från ett godartat förstadium, Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. Treatment advances such as the introduction of the standardized surgical technique total mesorectal excision (TME), pre-operative radiotherapy, and adjuvant chemotherapy have reduced the previously high local recurrence rates and improv
Rare variant, gene-based association study of hereditary melanoma using whole-exome sequencing
Aggrecan governs intervertebral discs development by providing critical mechanical cues of the extracellular matrix
Aggrecan (ACAN) is localized in the intervertebral disc (IVD) in unique compartment-specific patterns where it contributes to the tissue structure and mechanical function together with collagens. The extracellular matrix (ECM) of the IVD undergoes degenerative changes during aging, misuse or trauma, which inevitably alter the biochemical and biomechanical properties of the tissue. A deeper underst
Super-Earth of 8 M⊕ in a 2.2-day orbit around the K5V star K2-216
Context. Although thousands of exoplanets have been discovered to date, far fewer have been fully characterised, in particular super-Earths. The KESPRINT consortium identified K2-216 as a planetary candidate host star in the K2 space mission Campaign 8 field with a transiting super-Earth. The planet has recently been validated as well. Aims. Our aim was to confirm the detection and derive the main
