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Popular Abstract in Danish Genterapi er en attraktiv terapiform mod neurologiske lidelser som Parkinsons sygdom og epilepsi af flere grunde. Gener med en terapeutisk effekt kan introduceres lokalt ved præcise injektioner i det syge væv, hvor genproduktet kan frigives fra nerveceller i respons til aktivitet i det omgivende væv. Ved genterapi omgås den forhindring som blod-hjernebarrieren udgør, ligGene therapy is an attractive strategy for neurological disorders, such as Parkinson’s disease and epilepsy, for several reasons. Introduction of genes with a therapeutic potential can be achieved locally, by accurate injections in the compromised tissue, and release of a transgene therapeutic substance can be regulated by the surrounding host neural circuitry. The gene therapy approach circumvent

A new, two-layer canopy module with thermal inertia as part of the detailed snow model SNOWPACK (version 3.2.1) is presented and evaluated. As a by-product of these new developments, an exhaustive description of the canopy module of the SNOWPACK model is provided, thereby filling a gap in the existing literature. In its current form, the two-layer canopy module is suited for evergreen needleleaf f

Den här avhandlingen kombinerar vetenskapen om komplexa adaptiva system med ekonomiska geografi för att beskriva och undersöka självorganiserande principer och drag i täta urbana ekonomier, särskilt med avseende på flöden av information och kunskap mellan människor som ger upphov till produktivitetsrelaterade externaliteter. Avhandlingen består av en kappa som presenterar det övergripande ramverkeThis doctoral thesis combines complexity science and economic geography in order to explore bottom-up, self-organizing principles within urban economies, in particular in relation to the flow of information and knowledge between people. The thesis consists of a kappa that covers the general theoretical framework and four papers. The papers cover urban scaling and intra-urban scaling analysis, loca

Denna studie behandlar barnpornografibrottets placering i Brottsbalken (BrB). Uppsatsens syfte är att utreda barnpornografibrottets placering i BrB och dess bakomliggande skäl. Placeringen av barnpornografibrottet granskas ur ett allmänkritiskt perspektiv, men även med ett barnperspektiv. Framställningen beskriver gällande rätt och brottets placering i ljuset av brottets skyddsintressen. Studien bThis thesis discusses the crime of child pornography and its placement in Swedish criminal law, “Brottsbalken” (BrB). The purpose of the thesis is to examine the placement of the crime in BrB and the reasons behind the placement. The placement of the crime is viewed with a general critical perspective, but also with a child perspective. The thesis describes how the law is designed and the placemen

This master’s thesis project report deals with the design of multiplier for the reference signal to the Phase Locked Loop (PLL) used in WLAN application. The reference multiplier designed is based on a newly proposed architecture of dual loop feedback Delay Locked Loop (DLL) in which multiplication is performed within the loops. To lock the DLL, input signal is required to be delayed only for threKamal Kumar Gupta DLL Based Reference Multiplier for the use in a PLL for WLAN applications In modern wireless communication system, a frequency synthesizer/multiplier is one of the main building blocks of the system. For on-chip application, a frequency synthesizer is used as local oscillator (LO) to generate precise frequency from a single base frequency source, usually a crystal oscillator. Th

Automatiska förlängningar av avtal innebär att en ny bindningstid inträder om konsumenten inte senast vid viss tidpunkt säger upp avtalet. Att konsumentens passivitet är den omständighet som gör att den nya avtalstiden inträder, har bland annat gjort att sådana förlängningar jämförts med negativ avtalsbindning, vilket svensk rättsordning inte accepterar. Situationen är emellertid annorlunda när paAutomatic extension of contracts means that time-limited contracts are automatically extended unless the consumer terminates the contract a certain amount of time before it is to expire. The fact that the consumer’s inactivity is the reason why the contract is being extended has even led to a comparison between such automatic extensions and an illegal form of contracting called negative contract b

Emittenters skyldighet att offentliggöra insiderinformation enligt marknadsmissbruksförordningen (MAR) är betydelsefull för att upprätthålla en transparent och effektiv värdepappersmarknad med allmänhetens förtroende. Syftet med denna uppsats var att undersöka de bedömningar emittenten ställs inför till följd av MAR när information som potentiellt utgör insiderinformation uppstår inför offentliggöIssuers’ duty to disclose inside information according to the market abuse regulation (MAR) is important in order to maintain a transparent and efficient market with the confidence of the public. The purpose of this essay was to examine the assessments faced by the issuer as a result of MAR when information that could constitute inside information arises prior to the disclosure of an interim repor

The recovery of ‘waste heat’ from industrial and urban processes could meet a significant share of heating demands in urban and semi-urban areas. Replacing conventional heat sources in district heating (DH) systems with recovered heat could decrease primary energy inputs in a sector that globally relies to 90% on fossil fuels. Yet, despite the environmental, social, and economic benefits of waste

Title: “Language is access to everything” - A qualitative study of SFI-teachers' experience of the transition to digitalized distance education. Authors: Rania Elwan and Fitore Mehmeti Supervisor: Karin Kullberg Assessor: Maria Bergendal Arvidsson The purpose of the study is to investigate from teachers for Swedish for immigrants (SFI) perspective how the transition to digitalized distance ed

Food insecurity is a reality faced by millions of people worldwide. Poor access and availability to food markets, poverty, and uncertain global system futures all exacerbate this issue. In seeking to combat food insecurity for South Carolina residents and improve the viability and resilience of local food markets around Greenville County, South Carolina, this assessment determines optimal potentia

Background Coronary artery disease is one of the most common causes of death. A common cardiac examination is to give a visualization of the myocardial blood flow by injecting a radio pharmaceutical and detect the radiation with a camera. The camera has for decades been using thallium doped sodium iodide (NaI(Tl)) as the detector material. New detector materials have been developed because of the

Purpose: Within the construction business pricing is traditionally done at current account. The purpose of this report is to investigate why pricing levels are low within the construction consultant industry in comparison to other consultant industries, as well as to examine what affects the choice of pricing models. In addition to this the report aims to analyze pricing models used today and to d

The social and environmental impacts associated with corporate water use and discharge in Kazakhstan is historically high, and in certain watershed pose a significant threat to the health of the local communities and ecosystems. Today the industries are consuming almost a third of freshwater and remain one of the biggest polluters in the country. The situation is aggravated with the changing clima

Infrared (IR) spectroscopy has many advantages over optical, one of which is allowing us to see through intergalactic dust, letting us probe deeper into space and dust-dense regions such as galactic centers. However the investigating the IR spectral range is a relatively new field, owing to recent developments in detector technology, and stellar parameter determination in IR is not well researchedMillions of stars litter the night sky, and our understanding of how they were born is still developing. These burning orbs of gas are so far away that even the light they give off takes years to arrive to us on Earth. So how are we to measure anything about them if sending any equipment to their distant locations is unimaginable? Since the days of Newton, the only way we have been able to say any

The present study investigated second language (L2) learners’ processing of filler-gap dependencies and tested the implications of Clahsen and Felser’s (2006) shallow structure hypothesis according to which L2 learners underuse syntactic information during the processing of these sentence types. Advanced L2 learners of English (native Swedish speakers) listened to English sentences with object-rel

Carbon emissions have recently been put under the spotlight since it is widely accepted that global warming is caused by the emission of greenhouse gases, of which carbon dioxide is the main component. One of the fastest rising sources of emissions from carbon emissions is the transport sector, with emissions often rising faster than the GDP growth rates of developing countries. The estimated shar

Syftet med detta examensarbete är att vidga min förståelse för färg som skapande verktyg av arkitektur i rumslighet. Studien fokuserar på olika rumsliga fenomen som kan uppkomma beroende på hur färg samspelar med objekt, ytor och rumslighet. Parallellt med detta identifieras olika verktyg och praktiseras sedan i syfte att hitta sätt för färg att vara med i den tidiga designprocessen. För att samlaThe purpose of this thesis is to broaden my understanding of color as a creative tool of architecture in spatiality. The study will focus on different spatial phenomenons that can arise depending on how color interacts with objects, surfaces and spatiality. Parallel to this, different tools will be identified and then practiced in order to find ways for color to be included in the early design pro

Different actors identified the circular economy (CE) as a solution to tackle global environmental challenges and foster sustainable growth. Transitioning to CE requires new circular business models (CBM), which create, capture, and deliver value, based on the principles of the CE. It is, however, a challenging process for companies see through the wide variety of CBM types and to identify which C