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Myfab annual report 2021 The Swedish Research Council, Dnr. 2019-00207 – Myfab 5 Myfab Report 2021 Myfab - The Swedish Research Infrastructure for Micro and Nano Fabrication www.myfab.se 2 INTRODUCTION Myfab, founded in 2004, is a national facility since 2010 and is Sweden’s open-access research infrastructure (RI) for micro a nd nano fabrication with four cleanroom laboratories: Myfab Chalmers, M

https://www.nano.lu.se/sites/nano.lu.se/files/2023-02/Myfab%20annual%20report%202021%20final.pdf - 2026-06-30

We studied the role of arachidonic acid metabolites, histamine, and 5-HT in airway responses to trimellitic anhydride (TMA) in actively sensitized guinea pigs. Sensitization was produced by two intradermal injections of free TMA (0.1 ml of 0.3% TMA in corn oil). After 21 to 28 days, guinea pigs were anesthetized and challenged with intratracheal instillation of 0.5% TMA conjugated to guinea pig se

Ultra-fast substitution of chloride for bromide, iodide, azide and thiocyanate trans to ethene in Zeise's anion, [PtCl3(C2H4)](-), 1, has been investigated in methanol solvent by use of cryo temperature diode array stopped-flow spectrophotometry. Reactions follow the usual two-term rate law for square-planar substitutions, k(obs)=k(1)+k(2)[Y] (where k(1)=k(MeOH) [MeOH]), with k(1)=118+/-10 s(-1) a

Background:Membranous expression of the anti-adhesive glycoprotein podocalyxin-like (PODXL) has previously been found to correlate with poor prognosis in several major cancer forms. Here we examined the prognostic impact of PODXL expression in urothelial bladder cancer.Methods:Immunohistochemical PODXL expression was examined in tissue microarrays with tumours from two independent cohorts of patie

X-ray spectroscopy studies of potassium intercalated metal-free phthalocyanine multilayers adsorbed on Al(110) have been undertaken. Photoelectron spectroscopy measurements show the presence of several charge states of the molecules upon K intercalation, due to a charge transfer from the alkali. In addition, the comparison of valence band photoemission spectra with the density functional theory ca

We have studied how backbone N-H S-2 order parameters calculated from molecular dynamics simulations depend on the method used to calculate them, the starting conditions, and the length of the simulations. Using the carbohydrate binding domain of galectin-3 in the free and lactose-bound states as a test case, we compared the calculated order parameters with experimental data from NMR relaxation. T

Paediatric B-cell precursor acute lymphoblastic leukaemias (BCP ALL) with IKZF1 deletions (∆IKZF1) are associated with a poor outcome. However, there are conflicting data as to whether ∆IKZF1 is an independent risk factor if minimal residual disease (MRD) and other copy number alterations also are taken into account. We investigated 334 paediatric BCP ALL, diagnosed 1992-2013 and treated according

The free neutral nanoscale NaCl clusters have been produced in a beam and studied with x-ray photoelectron spectroscopy. High resolution spectra simultaneously containing cluster and molecular-monomer, featuring in both the valence and core-level Na 2p and Cl 2p regions, have been obtained. Cluster-level energy shifts of around 3 eV toward lower binding energy for Na 2p and approximate to 1 eV tow

This study reports the outcome of active surveillance in men with PSA screening-detected prostate cancer (PC), and PSA doubling time (PSADT) was evaluated as a predictor of selecting patients to active treatment or surveillance. On December 31, 1994, 10,000 men were randomized to biennial PSA testing. Through to December 2004, a total of 660 men were diagnosed with PC, of whom 270 managed with ini

This study addresses how humic substance (HS) chemical composition and photoreactivity affect bacterial growth, respiration, and growth efficiency (BGE) in lake water. Aqueous solutions of HSs from diverse aquatic environments representing different dissolved organic matter sources (autochthonous and allochthonous) were exposed to artificial solar UV radiation. These solutions were added to lake w

Macroporous gels (MGs) with a broad variety of morphologies are prepared using the cryotropic gelation technique, i.e. gelation at subzero temperatures. These highly elastic hydrophilic materials can be produced from practically any gel-forming system with a broad range of porosity extending from elastic and porous gels with pore sizes up to 1.0 mu m to elastic and sponge-like gels with pore sizes

In recent years, nanostructure technology involving Ill-V semiconductors have made significant progress in areas such as optoelectronics and spintronics. A number of new materials and nanostructures have been invented, most of them being of a very dilute character or extremely small. Because of these properties, their structural characterization on an atomic scale is of profound importance. One im

The effect of reaction parameters on lipase-mediated chemo-enzymatic epoxidation of linoleic acid was investigated. Hydrogen peroxide was found to have the most significant effect on the reaction rate and degree of epoxidation. Excess of hydrogen peroxide with respect to the amount of double bonds was necessary in order to yield total conversion within a short time period, as well as at temperatur

We have studied the epitaxial growth and electrical performance of Al-free, GaAs-based, resonant tunnelling diodes (RTDs) including thin barriers of GaInP, GO, or GaAsxP1-x. n-Type tunnelling diodes have been fabricated and the symmetry in the current-voltage (I-V) characteristics, as well as the peak-to-valley ratios, are found to be sensitive probes for the inter-face quality in the heterostruct

A high-power laser facility has been established at the Lund Institute of Technology, Sweden, available to national groups and their international collaboration partners. The laboratory incorporates three major 10 Hz laser systems, that can be operated individually or synchronized in combined use. Each system represents extreme optical powers in a certain sense. The main system is a terawatt laser

Context: Pediatric cancer treatment may imply an increased risk of hypogonadism, leading to metabolic disorders and osteoporosis. Such complications are potentially preventable. Objective: The aim of this study was to assess diagnosis- and treatment-dependent risk of hypogonadism in male childhood cancer survivors (CCS). Design: Male CCS who were treated during the period 1970-2002 and who in 2004

Background: Creatinine-based estimated glomerular filtration rate (eGFR) equations are widely used in clinical practice but exhibit inherent limitations. On the other side, measuring GFR is time consuming and not available in routine clinical practice. We developed and validated machine learning models to assess the trustworthiness (i.e. the ability of equations to estimate measured GFR (mGFR) wit

We present a new phase-separated Zr-based metallic glass (MG) composition, free of toxic elements (Ni and Cu) prepared in a glass-forming system by alloying addition. The substitution of Y in Zr70-xAl12.5Fe17.5Yx (x = 0–15 at.%) results in phase separation, giving rise to nano-amorphous domains in a glassy matrix. A homogeneous MG feature is observed for low concentrations of Y up to x = 5. Micros

While NH3 has gained a lot of interest as a potential carbon-free fuel, at present, there are notable disagreements when it comes to predictions of some of its combustion characteristics, such as burning velocity or species mole fractions, in particular of NOx, which have the potential to cause significant harm to both human health and the environment. Nevertheless, because the NH3 flame presents