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Between 1992 and 2008, 713 high hyperdiploid acute lymphoblastic leukemias in children aged 1-15 years were diagnosed and treated according to the Nordic Society for Pediatric Hematology and Oncology acute lymphoblastic leukemia 1992/2000 protocols. Twenty (2.8%) harbored t(1;19), t(9; 22), der(11q23), or t(12; 21). The median age of patients with "classic" high hyperdiploidy was lower than that o

Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of serum testosterone's high heritability, we performed a meta-analysis of genome-wide association data in 8,938 men from seven cohorts and followed up the genome-wide significant findings in one in silico (n = 871) and two de novo repl

Background The aim of this study was to investigate gene transfer to human umbilical cord blood (CB) CD34(+)/CD38(low) and NOD/SCID repopulating cells using oncoretroviral vectors and to compare the transduction efficiency using three different viral envelopes. Methods CB cells were transduced on Retronectin using an MSCV-based vector with the gene for GFP (MGIN), which was packaged into three dif

Background: We evaluated the association of total and free forms of serum human kallikrein 2 (hK2) and prostate-specific antigen (PSA) with prostate cancers of unfavorable prognosis. Methods: We retrospectively measured total PSA (tPSA), free PSA (fPSA), and total hK2 (thK2) in preoperative serum samples from 867 men [and assessed free hK2 (fhK2) measured in 577 of these men] treated with radical

Abstract in Undetermined Previous work has presented contrasting views of the last glaciation on Jameson Land, central East Greenland, and still there is debate about whether the area was: (i) ice-free, (ii) covered with a local non-erosive ice cap(s), or (iii) overridden by the Greenland Ice Sheet during the Last Glacial Maximum (LGM). Here, we use cosmogenic exposure ages from erratics to reconc

Intensive insulin therapy, aiming for strict normoglycaemia, is associated with increased survival in critically ill patients. Insulin therapy concomitantly reduces plasma-free fatty acids. Recent studies indicate that free fatty acids mediate inflammation. In addition to plasma glucose and free fatty acid-lowering effects, insulin also has anti-inflammatory properties. This study was designed to

In a controlled prospective randomized study the regimen doxorubicin (A) 40 mg/m2 + melphalan (M) 0.4 mg/kg was compared with A + M + cisplatin (C) 50 mg/m2 given every four weeks in advanced ovarian cancer, FIGO stage III or IV and with serous or anaplastic histology. From 1981 to 1983, 300 patients entered the study and 295 patients were evaluable for response, toxicity and long-term survival. A

The concept of measuring the proportions of various forms of PSA in serum, particularly the proportion of free to total PSA, represents a new and exciting method of detecting early curable prostate cancers and avoiding unnecessary prostate biopsies in men who have BPH only. Compared with other methods of improving diagnostic specificity, it does not require transrectal ultrasound for determination

A computer program for preliminary cost estimates of free and immobilized enzyme systems has been developed. The cost for the hydrolysis of lactose by β-galactosidase fromAspergillus oryzae has been calculated for a batch tank reactor, with free (BTRF) and immobilized (BTRI) enzymes, a continuously stirred tank reactor (CSTR) and a plug-flow tubular reactor (PFTR), considering the mass transfer be

Prostate-specific antigen (PSA) and human prostatic glandular kallikrein (hK2) have 79% identity with the primary structure. When we used recombinant hK2 protein, only 7 of 23 monoclonal anti-PSA IgGs (monoclonal antibodies, MAbs) cross-reacted with hK2, which enabled us to design a novel immunofluorometric MAb-MAb assay for the specific detection of hK2. In the first incubation, an excess of MAb

LL_SMMV11_eng_HT21_rev210505 Reading list for Introduction to service management, 7,5 hp (SMMV11) The reading list was approved by the Board of the Department of Service Management and Service Studies 2019-04-24, latest revised 2021-05-05. The reading list is valid from 2021-08-31. Adib, Amel & Guerrier, Yvonne. (2003). ‘The interlocking of gender with nationality, race, ethnicity and class: the n

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2021-05/LL_SMMV11_eng_HT21_rev210505.pdf - 2026-05-18

Mer makt åt akademiska ledare! Bränslecell driver framtidens bil Klimatmätning på hög nivå Arabisk höst Lunds universitets magasin | nr 9 | 2012 demokrater driLLas i oPinionsBiLdning 2 LUM nr 9 | 2012 LUM nr 9 | 2012 3 – Ska vi ta något om artificiell fotosyntes – att kunna efterlikna naturen vore ju fantastiskt, men det kanske är för bra för att vara sant? Eller satsa på nanotrådar som kan minska

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-9-2012.pdf - 2026-05-18

Due to the present shortage of He-3 and the associated tremendous increase of its price, the supply of large neutron detection systems with He-3 becomes unaffordable. Alternative neutron detection concepts, therefore, have been invented based on solid B-10 converters. These concepts require development in thin film deposition technique regarding high adhesion, thickness uniformity and chemical pur

Multiplex separation of mixed cell samples is required in a variety of clinical and research applications. Herein, we present an acoustic microchip with multiple outlets and integrated pre-alignment channel to enable high performance and label-free separation of three different cell or particle fractions simultaneously at high sample throughput. By implementing a new cooling system for rigorous t

All organic solvent waste should be separated into:Halogenated wasteNon-halogenated wasteNote that the organic solvent waste category excludes ethers. For details regarding the disposal of ethers, see section 8.2 Chemical Waste. Additionally, oil is categorized as chemical waste and must be stored in sealed, leak-proof containers. For more information on handling oil waste, see section 8.2 Chemica

https://www.kc.lu.se/en/employee/general-safety-regulations/8-waste-handling/81-organic-solvent-waste - 2026-05-17

21 May 2026 13:00 to 14:25 | Other Do you find it hard to get started with your writing? Is your text not progressing even though the deadline is approaching? Would you like some company while writing? Join "Shut up and write"! "Shut up and write" is a shared digital writing session where you, together with other students and a librarian, focus on your own writing. The session consists of three sh

https://www.science-library.lu.se/calendar/shut-and-write-2 - 2026-05-17

28 May 2026 13:00 to 14:25 | Other Do you find it hard to get started with your writing? Is your text not progressing even though the deadline is approaching? Would you like some company while writing? Join "Shut up and write"! "Shut up and write" is a shared digital writing session where you, together with other students and a librarian, focus on your own writing. The session consists of three sh

https://www.science-library.lu.se/calendar/shut-and-write-3 - 2026-05-17