Sökresultat

Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular hierarchy in GBM and have a determining role in tumor growth, recurrence and patient prognosis. However, a better definition of GSC subpopulations, especially at the surgical resection margin, is warranted for improved oncological treatment options. T

The decarbonisation of energy systems is leading to a reconfiguration of the geographies of energy. One example is the emergence of community energy, which has become a popular object of study for geographers. Although widely acknowledged to be a contested, capacious, and flexible term, “community energy” is commonly presented as singular, bounded, and localised. In this paper, we challenge this c

In recent years the term ‘energy democracy’ has become increasingly popular, especially in the context of aspirations for a low-carbon transition that include wider socio-economic and political transformation. The emergence of ‘energy democracy’ is thus part of a broader trend in research and practice which has sought to foreground the 'stuff’ of politics. Yet, unlike the more academically develop

There is a growing ‘energy democracy’ (ED) movement which regards the transition to renewable energy as an opportunity for socio-economic transformation, as well as technological innovation. The literature on ED tends to associate greater democratic control of energy systems with increased community control over the means of energy generation and distribution. Nonetheless, this literature often as

Using a case study of the Búrfell wind farm project, a large wind farm proposed in the Central Highlands of Iceland, the authors attempt to provide new insights into the factors shaping subjective landscape perceptions and attitudes to renewable energy developments, and into alternative methods that may be used for their assessment. The research was based on an on-site visit and actual experience

For rural communities, energy projects can provide a host of benefits, and yet also be a source of significant conflict. Place attachment has become an increasingly popular concept for understanding local responses to large scale renewable energy installations. However, there has been significantly less attention paid to how place attachment influences local responses to community-led developments

The community energy sector is widely understood to be a pluralistic sector, encompassing a broad range of aims, motivations, and practices. This heterogeneity is, however, still not very well understood. Dominant analytical frameworks in the study of energy geographies offer little in the way of exploring the diversity of motivations, visions, and social relations that are present within the comm

This study provides insights into the external powers that can influence business leaders' communication on sustainability. It shows how the socio-political context manifested in national and transnational policies, regulations and other socio-political events can influence the CEO talk about sustainability. Design/methodology/approach: This study adopts an interpretative and qualitative method of

The incidence of Human Papillomavirus positive (HPV+) tonsillar cancer has been sharply rising during the last two decades. Myeloid cells represent an appropriate therapeutic target due to their ability to orchestrate antigen-specific immunity within the tonsil, the availability of viral antigens, and the proximity of the tumor and the underlying lymphoid tissue. However, the interrelationship of

This study contributes to the sparse literature on differences between public and private primary care practices (PCCs). The purpose was to explore if differences in performance and characteristics between public and PCCs persist over time in a welfare market with patient choice and provider competition, where public and private providers operate under similar conditions. The analysis is based on

Tonsillar cancer (TC) is a subset of head and neck cancer (HNC). TC incidence is sharply rising due to an increased prevalence of human papillomavirus (HPV) infection in the western world. Currently HPV status is considered during clinical staging due to its positive association to patient prognosis. Presumably, the relation between HPV and patient survival is dependent on the generation of an eff

The 68-kDa homodimeric 3C-like protease of SARS-CoV-2, Mpro (3CLpro/Nsp5), is a key antiviral drug target. NMR spectroscopy of this large system proved challenging and resonance assignments have remained incomplete. Here we present the near-complete (>97 %) backbone assignments of a C145A variant of Mpro (MproC145A) both with, and without, the N-terminal auto-cleavage substrate sequence, in its na

This chapter introduces the project of this volume, laying out the coordinates of the phenomena and the questions addressed in the book. After reviewing the enduring significance of territories in the current historical context, we situate the science of territories in terms of its theoretical foundations and continuing dialogue with other threads in the social sciences. We then present to the rea

The support from SSM has made it possible to continue collecting brown algaefrom the place on the Swedish west coast where regular collections began asearly as 1967. The support has also enabled more extensive analyses ofpreviously collected material than was possible before. This applies to bothsupplementary analyses of previously reported radionuclides and analysis ofnew ones. The project has al

Diverse bilingual experiences have implications for language comprehension, including pragmatic elements such as verbal irony. Irony comprehension is shaped by an interplay of linguistic, cognitive, and social factors, including individual differences in bilingual experience. We examined the relationship between individual differences related to bilingualism, specifically, the capacity to understa

OBJECTIVE: Few studies address results from use of new technology and patient participation in hypertension management. The PERHIT Study is a multicentre randomised controlled trial with the aim to evaluate the effects of a person-centred approach using a web-based, interactive self-management system through the patient´s own mobile phone on blood-pressure and well-being. Primary aim is the degree

The salinization of freshwaters is a global threat to aquatic biodiversity. We quantified variation in chloride (Cl−) tolerance of 19 freshwater zooplankton species in four countries to answer three questions: (1) How much variation in Cl− tolerance is present among populations? (2) What factors predict intraspecific variation in Cl− tolerance? (3) Must we account for intraspecific variation to ac