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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of caffeine compared to aminophylline or theophylline in preterm infants at risk of apnea, with apnea, or in the peri-extubation phase.
Glypicans (GPC1-6) are associated with tumorigenic processes and their involvement in neoplastic behavior has been discussed in different cancer types. Here, a cancer-wide GPC expression study, using clinical cancer patient data in The Cancer Genome Atlas, reveals net upregulation of GPC1 and GPC2 in primary solid tumors, whereas GPC3, GPC5 and GPC6 display lowered expression pattern compared to n
The electrochemical growth of Au nanowires in a template of nanoporous anodic aluminum oxide was investigated in situ by means of grazing-incidence transmission small- and wide-angle x-ray scattering (GTSAXS and GTWAXS), x-ray fluorescence (XRF), and two-dimensional surface optical reflectance. The XRF and the overall intensity of the GTWAXS patterns as a function of time were used to monitor the
The activation of G Protein-Coupled Receptor 56 (GPR56), also referred to as Adhesion G-Protein-Coupled Ceceptor G1 (ADGRG1), by Collagen Type III (Coll III) prompts cell growth, proliferation, and survival, among other attributes. We investigated the signaling cascades mediating this functional effect in relation to the mitochondrial outer membrane voltage-dependent anion Channel-1 (VDAC1) expres
Background Women's pregnancy history is associated with incident risk of coronary artery disease with some evidence also suggesting a relevance for prognosis following treatment. Objectives To study the associations between maternal history of preterm delivery, a history of small for gestational age infant, parity and age at first delivery with clinical restenosis after percutaneous coronary inter
Group B streptococcus (GBS) is a leading cause of life-threatening neonatal infections and subsets of adverse pregnancy outcomes. Essentially all GBS strains possess one allele of the alpha-like protein (Alp) family. A maternal GBS vaccine, consisting of the fused N-terminal domains of the Alps αC and Rib (GBS-NN), was recently demonstrated to be safe and immunogenic in healthy adult women. To enh
We study the transient dynamics subject to quantum coherence effects of two interacting parallel quantum dots weakly coupled to macroscopic leads. The stationary particle current of this quantum system is sensitive to perturbations much smaller than any other energy scale, specifically compared to the system-lead coupling and the temperature. We show that this is due to the presence of a parity-li
We report on a combined experimental and theoretical study on CrI3 single crystals by employing the polarization dependence of resonant inelastic x-ray scattering (RIXS). Our investigations reveal multiple Cr 3d orbital splitting (dd excitations) as well as magnetic dichroism (MD) in the RIXS spectra. The dd excitation energies are similar on the two sides of the ferromagnetic transition temperatu
The self-screening error in the random-phase approximation and the GW approximation (GWA) is a well-known issue and has received attention in recent years with several methods for a correction being proposed. Here, we apply two of these, a self-screening and a so-called self-polarization correction scheme, to model calculations to examine their applicability. We also apply a local form of the self
Reading out the parity degree of freedom of Majorana bound states is key to demonstrating their non-Abelian exchange properties. Here, we present a low-energy model describing localized edge states in a two-arm device. We study parity-to-charge conversion based on coupling the superconductor bound states to a quantum dot whose charge is read out by a sensor. The dynamics of the system, including t
Diffusion NMR and MRI methods building on the classic pulsed gradient spin-echo sequence are sensitive to many aspects of translational motion, including time and frequency dependence ("restriction"), anisotropy, and flow, leading to ambiguities when interpreting experimental data from complex heterogeneous materials such as living biological tissues. While the oscillating gradient technique speci
The rapid spread of monkeypox (mpox) has been declared as a public health emergency of international concern (PHEIC). The present study aimed to assess the knowledge, attitude, and worry levels of the general population in the Kurdistan region of Iraq regarding the ongoing mpox multi-country outbreak. An online cross-sectional survey was conducted between 27–30 July 2022, using a convenience sampl
Despite recent therapeutic advances, pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies, with remarkable resistance to treatment, poor prognosis, and poor clinical outcome. More efficient therapeutic approaches are urgently needed to improve patients’ survival. Recently, the development of organoid culture systems has gained substantial attention as an emerging
The nature of the few known solar-mass stars simultaneously containing debris disks and planets remains an open question. A number of works have shown that this property appears to be independent of planetary masses as well as of stellar age, but possible correlations with stellar kinematics and metallicity have not been investigated. In this paper, we show that the majority of known stars contain
Atmospheric inversions provide estimates of carbon dioxide (CO2) fluxes between the surface and atmosphere based on atmospheric CO2 concentration observations. The number of CO2 observations is projected to increase severalfold in the next decades from expanding in situ networks and next-generation CO2-observing satellites, providing both an opportunity and a challenge for inversions. This study i
We previously showed that two iron compounds that are orally ingested by humans, namely ferric EDTA and ferric citrate, can induce an oncogenic growth factor (amphiregulin) in human intestinal epithelial adenocarcinoma cell lines. Here, we further screened these iron compounds, plus four other iron chelates and six iron salts (i.e., 12 oral iron compounds in total), for their effects on biomarkers
Background Type 2 (T2) high asthma is recognised as a heterogenous entity consisting of several endotypes; however, the prevalence and distribution of the T2 biomarkers in the general asthma population, across asthma severity, and across compartments is largely unknown. The objective of the present study was to describe expression and overlaps of airway and systemic T2 biomarkers in a clinically r
Ultrafast (UF) dynamic contrast-enhanced (DCE)-MRI offers the potential for a faster and, therefore, less expensive examination of breast lesions; however, there are no reports that have evaluated whether UF DCE-MRI can be used the same as conventional DCE-MRI in the reading of morphological information. This study evaluated the agreement in morphological information obtained from malignant breast
