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Popular Abstract in Swedish Många av de föreningar som utvecklas i den farmaceutiska industrin idag har sina rötter i naturprodukter. Paclitaxel, den aktiva substansen i läkemedlet Taxol, återfinns bland annat i idegranens bark. Detta upptäcktes i början av 1960-talet då ett nationellt sökprogram för att finna nya naturprodukter för användning mot cancer organiserades i Amerika. Den låga halten avMany of the drugs that are developed in the pharmaceutical industry have their origin in natural products. Paclitaxel, the active substance of the medicine Taxol, was found in the bark of the Pacific yew tree (Taxus brevifolia). This was discovered in the early 1960's when a screening program was initiated by the National Cancer Institute (NCI) in the US, with the aim to find new natural products

Future historians might remember the period 2009-2012 as a turning point in the political response to global warming and climate change. The 1980s were a time of agenda-setting in which climate change became accepted as a political problem; the 1990s saw the first institutionalization through adoption of the United Nations Framework Convention on Climate Change in 1992 and its Kyoto Protocol in 19

A mysterious serial killer is hunting other serial killers - and one FBI agent suspects there may be more to the vigilante than they imagine.

Supplemental Instruction (SI) är som framgår av namnet ett komplement till den ordinarie undervisningen i en kurs. Tanken med SI är att inlärningen av ett ämne förstärks genom utbyte av tankar och idéer mellan studenterna. Vid LTH är SI-verksamheten knuten till en initiell ”svår” kurs för nybörjarstudenter. SI sker i möten om ca 5-15 studenter där diskussionen leds av en äldre student. Den äldre s

Popular Abstract in Icelandic Við könnumst flest öll við prótín (eggjahvítuefni) af innihaldslýsingu hvers kyns matvæla. En prótín eru annað og meira en bara orkugjafi. Prótín gegna fjölmörgum veigamiklum hlutverkum í nær öllum líffræðilegum ferlum. Þau hraða ýmsum efnahvörfum, flytja efni í gegnum frumuhimnur, aðstoða við boðskipti bæði innan og á milli fruma, og gegna mikilvægu hlutverki í starfAlthough organisms have evolved sophisticated cellular mechanisms for regulating their various protein networks, proteins sometimes start to clump together in an uncontrolled way. The aggregation of proteins has been associated with a range of serious diseases. In this thesis we develop and apply theoretical computer models to investigate different aspects of the aggregation process, and its under

In this contribution, we elaborate the material force method with application to standard dissipative materials, in particular crystal-(elasto)plasticity. It thereby turns out that material heterogeneities caused by the gradient of the corresponding slip parameters induce additional material volume forces. As a result, we observe that these forces contribute to computations of typical boundary val

The aim of this thesis is to describe how the luminosity can be measured in the ATLAS experiment at the Large Hadron Collider. Luminosity is a fundamental quantity that is used in most physics studies at the LHC. For example in order to measure cross sections. Firstly, the detector description of LUCID which has been implemented in the global ATLAS software framework is described and validated. Se

The purpose of this paper is to perform a detailed examination of corruption effects on trade based on corruption characteristics known to affect economic exchange within the corruption research field. These characteristics are the level, prevalence, customs location, function and predictability of corruption. The multifaceted corruption impact on trade is empirically examined using a corrupti