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Trans* parenthood & « doing family »: Understanding parenthood in practices

Trans parenting, scarcely explored in scientific literature, is often treated through the lens of accessibility to procreation technology, state of legislation or experiences of family continuity. A “doing family practice” approach allows us to explore how trans parenthood is conceived in actions for trans parents in France. Through narrative interviews, a “doing family” approach to parenthood, an

The Evolution of ASEAN’s Neutrality Norm in the Era of US-China Competition

Against the backdrop of escalating US-China competition, the Association of Southeast Asian Nations (ASEAN) is situated in a key geopolitical position. This is not the first time ASEAN has faced great power competition within the region. During the Cold War, to respond to the US-Soviet rivalry, ASEAN developed neutrality as one of its fundamental norms. This thesis aims to explore the role and evo

Long-term pain and health economic outcomes in adults receiving multidisciplinary CBT for chronic pain.

Introduction: The first-line evidence-based treatment for chronic pain is multidisciplinary treatment involving pain-focused CBT. Studies have shown that changes in psychological flexibility (PF) during pain-focused CBT positively mediatesoutcomes, even when the treatment does not specifically target PF. While CBT and PF-based treatments for chronic pain yield small to moderate, but clinically mea

A Daily Diary Study of Cancer-Related Pain and Associated Difficulties: The Role of Psychological Flexibility

Background: Approximately 40% of cancer patients/survivors develop chronic cancer-related pain (CRP), which is often associated with greater levels of fatigue and cancer worry, all of which are associated with poorer functioning, wellbeing, and greater healthcare costs. Psychological Flexibility (PF) refers to one’s level of openness to and acceptance of physical/emotional experiences and willingn

Prenatal exposure to air pollution and the development of autism spectrum disorder from birth to adolescence: A nationwide Danish cohort study

Background: Prenatal exposure to ambient air pollution has been linked to autism spectrum disorder (ASD), but evidence from low-exposure settings such as Denmark remains limited.Objective: We aimed to examine the association between prenatal exposure to particulate matter with a diameter of ≤2.5 µm (PM2.5), black carbon (BC), and nitrogen dioxide (NO2) and ASD in children, and to identify the most

Integrating Obesity Care into Chronic Disease Management in Catalonia : Progress and Challenges in Health System Approaches

BACKGROUND: Obesity represents a significant public health challenge, particularly in the context of coexisting chronic diseases and multi-morbidity. In Spain, and specifically in Catalonia, primary care plays a central role in prevention and management, yet barriers such as weight-related stigma can compromise care delivery.AIM: To evaluate the current state of obesity prevention and management w

Measuring and Managing Obesity in Pregnancy Using the Edmonton Obesity Staging System : A Scoping Review

Emerging evidence and clinical practice guidelines have highlighted that obesity, defined as a chronic disease characterised by excess or dysfunctional adipose tissue, may not be accurately measured or understood by solely relying on body mass index (BMI) which is a measure of size not functionality. An alternative to BMI, as proposed in the Canadian Adult Obesity Management Guideline, is the use

The associations of maternal exposure to black carbon and foetal growth risks in Southern Sweden.

Black carbon (BC) is an air pollutant of emerging concern, and further evidence is needed to understand its health effects. This study investigates the association between gestational BC exposure and birth outcomes, and whether these effects are independent of particulate matter with an aerodynamic diameter of ≤ 2.5 μm (PM2.5) exposure. We used data from the population-based birth cohort, Maternal

Streamflow Elasticity to Precipitation Distribution and Potential Evapotranspiration Across South America

This study examines the sensitivity of mean, high and low streamflows (i.e., Q elasticity) to changes in precipitation (P) and potential evapotranspiration (PET) across South America. The response to P was further assessed by intensifying its seasonal and daily distribution, specifically by increasing (decreasing) P during wet (dry) periods and high (low) events, while maintaining the annual P vol

Flow and Phenotype Determine Climbing Success in Juvenile European Eel (Anguilla anguilla) : A Test of Two Ramp Designs

The European eel (Anguilla anguilla) faces significant challenges during its migratory lifecycle due to anthropogenic habitat fragmentation. Fish passage solutions, such as eel ramps, aim to mitigate such barriers, but their effectiveness varies and may impose selective pressures on eel phenotypes. This study evaluates the impact of ramp design and water flow on the climbing success of juvenile ee

Spatial transcriptomics reveals a key role of fibroblast-like vascular smooth muscle cells in human atherosclerotic cell crosstalk and stability

BACKGROUND AND AIMS: Atherosclerotic plaques are the leading cause of cardiovascular events. Single-cell approaches have identified diverse human plaque cell phenotypes but their spatial distribution and interactions remain unclear. Here, intercellular communication patterns in human plaque microenvironments were mapped to reveal novel targets to prevent atherosclerotic events.METHODS: Spatial tra

The legality of weight discrimination in Canada : an environmental scan of case law and the limits of Canadian legislation

Weight stigma negatively impacts people with higher weights across the lifespan as well as social contexts and can lead to weight discrimination. As weight is not a protected identity in Canadian human rights legislation, it is important to better understand how weight discrimination is being argued in Canada’s legal system. The purpose of this environmental scan was to examine and describe Canadi

Detection of Acromegaly From Facial Images Using Machine Learning : A Comparison With Clinical Experts

Context Substantial diagnostic delay in acromegaly contributes to increased morbidity and mortality. Screening attempts in high-risk groups have yielded few positive cases, underscoring the need for simple and precise prescreening methods. Objective Machine-learning analysis of facial images shows promise for acromegaly detection but requires validation in larger, well-characterized cohorts using

Evaluation of biodiversity offsetting – a case study from a Swedish municipality

Biodiversity offsetting (BO) is aimed to counterbalance biodiversity impacts from development projects. In Sweden, interest in BO within urban planning has grown since the mid-to-late 1990s, when the approach was first piloted in the municipality of Lomma. Because urban planning often involves non-protected nature, BO is not legally mandated but instead implemented on a voluntary basis. So far, ev

Soot is in the air: the physiological impacts of air pollution in birds and bumblebees

Air pollution has become a widespread consequence of human activities, with increasing urbanization and a warming climate shaping its distribution and effects. Organisms with distinct respiratory systems and physiological traits are exposed to multiple air pollutants across human-modified environments, particularly in cities. However, much of our current understanding of how air pollutants affect

β-Blocker effects in huntington's disease : A caution on clinical interpretation

A recent retrospective analysis of Enroll HD data suggesting β-blockers slow Huntington's disease progression has triggered patient demand but requires caution. The findings rely solely on small observational subsets and are vulnerable to bias and confounding. A prior Mendelian-randomization study found no causal link between β-blockers and HD onset; instead, genetically higher blood pressure was

The effect of birth order on children's time use

Recent research shows that birth order affects human capital outcomes, yet there is limited empirical evidence on the underlying mechanisms. This study examines the effect of birth order on children's time use across activities that are important for human capital development. Using detailed time-use diaries of Australian children aged 2–15, we find that within families with two or three children,

Children's Experiences of Communication in Everyday Life Following Posterior Fossa Tumour Surgery—A Sense of Belonging While Navigating Reality

Background: Posterior fossa tumours (PFT) are the most common childhood brain tumours, and children treated for these tumours are at increased risk of persistent speech, language and/or communication difficulties. Such difficulties have often been described in association with the postoperative complication cerebellar mutism syndrome (CMS), but can also occur in children without a period of mutism