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Protein-carbohydrate interactions are of central role in all living organism. In the studies presented in this thesis several strategies for engineering such interactions have been investigated. In the first study the binding affinity of a carbohydrate binding module (CBM) was improved a 100-fold through affinity maturation. Also, in that study it was discovered that all the selected, matured muta
The problem of joint source-channel coding is considered for a stationary remote (noisy) Gaussian source and a Gaussian channel. The encoder and decoder are assumed to be causal and their combined operations are subject to a delay constraint. It is shown that, under the mean-square error distortion metric, an optimal encoder-decoder pair from the linear and time-invariant (LTI) class can be found
A summary of various tin analyses to date
An approach to loop-shaping feedback control design in the frequency domain via extremum seeking is proposed. Both plants and controllers are linear time-invariant systems of possibly infinite dimension. The controller is assumed to be dependent on a finite number of parameters. Discrete-time global extremum seeking algorithms are employed to minimise the difference between the desired loop shape
