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Background The distal forearm fracture is the most common fracture in children. To allocate health care resources and evaluate if prevention strategies have been successful, it is essential to monitor changes in the epidemiology of common fractures. Methods Our hospital serves a city in which year 2006 included 276,244 inhabitants (49,664 <17 years of age). Through the hospital archives, we identi
The imaging capabilities of an in-house X-ray setup for micro computed tomography, consisting of a photon-counting detector and a liquid target source, are reported here. The effect of the finite X-ray source spot size on the image resolution is measured using the slanted edge method at different sample-to-detector distances, and the energy response of the detector is probed using clinically relev
This study investigates how decision makers at the fire service responds to different types of information and how it can enhance fire service operations during incidents. Semi-structured interviews were conducted with 47 incident commanders from three countries (Sweden, Finland and USA) to assess the influence of pre-planned, real-time, and predictive information on decision-making. The results i
This report has been prepared with funding from the Nordic Council of Ministers by experts at HEUNI, Fafo and Lund university. The report is a response to a call by the Nordic Work Environment Committee in early 2024 seeking research on the relationship between labour market crime and work environment risks, with the aim of generating more knowledge and practical recommendations and solutions. The
Ultralow-cross-linked microgels serve as powerful model systems for investigating structure–rheology relationships in soft colloidal suspensions. Using precipitation polymerization, we obtain both self-cross-linked microgels with a weakly cross-linked core, surrounded by an ultrasoft corona (ULC), and regular cross-linked (RC) microgels. ULC microgel suspensions exhibit distinctive rheological res
Epigenome-wide studies of pancreatic islets provide valuable insights into type 2 diabetes (T2D) but lack methylomes from individual cell types. Here we show changes to alpha and beta cell-specific methylomes and transcriptomes from people with or without T2D, using whole-genome bisulfite sequencing and RNA sequencing. We discover 22,544 differentially methylated regions annotated to 7,975 genes i
Background: Dementia is a growing public health concern, and although diet is a modifiable potential risk factor, the role of free sugar intake remains unclear. Excess sugar has been linked to metabolic and cardiovascular dysfunction, both associated with cognitive decline, but evidence regarding specific sugar sources is limited. Objectives: This study aimed to investigate the associations betwee
Background and aims: We examined whether the excess cardiovascular disease (CVD) risk among adults with steatotic liver disease (SLD) subtypes could be reduced or eliminated through joint control of low-density lipoprotein cholesterol (LDL-C), lipoprotein(a) [Lp(a)], and high-sensitivity C-reactive protein (hs-CRP). Methods and results: This prospective cohort study included 291,995 participants f
This contribution to the conference on Transitioning away from Fossil Fuels focuses on thematic pillar 3 which addresses the advancement of international cooperation and climate diplomacy. The Fossil Fuel Treaty Initiative represents an opportunity to align climate ambition with human rights and biodiversity stewardship. We consider this stage of the process a crucial waypoint for responding in a
Bacteria encode diverse defence systems, including restriction-modification and CRISPR-Cas, that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstrate that many recently identified antiphage defence operons comprise a nuclease and NTPase protein, suggesting that additional nucleic acid-targeting systems remain to be understood. Here we develop large-scale compa
